DRSC/TRiP Functional Genomics Resources

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Protein Alignment SEC14L2 and CG10301

DIOPT Version :9

Sequence 1:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens
Sequence 2:NP_651173.2 Gene:CG10301 / 42797 FlyBaseID:FBgn0039106 Length:306 Species:Drosophila melanogaster


Alignment Length:273 Identity:68/273 - (24%)
Similarity:108/273 - (39%) Gaps:65/273 - (23%)


- Green bases have known domain annotations that are detailed below.


Human     8 LSPRQKEALAKFRENVQDVLPALPNPDDYFLLRW------LRARSFDLQKSEAMLRK---HVEFR 63
            |||    .|||..|...:..|.....|...|..|      ||||: |:....|.||:   .:|..
  Fly     5 LSP----TLAKLAEQEVNETPDRIQQDIIILRVWIRQQPHLRART-DVDFLIAFLRRCRYSLEET 64

Human    64 KQKDIDNIISWQP--PEVI------QQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL 120
            |:: ||...:...  ||::      |:.|.....|..|      |..:...|::..:|.|     
  Fly    65 KRR-IDRYFTHYNLFPEIMNNRCVTQRLLDINRMGVCL------YPDMPKGDSRSAMFIA----- 117

Human   121 LRTKMRECEL-LLQECAHQTTKLGRKVETITIIYD-------CEGLGLKHLWKPAVEAYGEFLCM 177
             |....:..| :|:|..|.::   ..:|.|.:..|       ||.:.|:.:....:..:...|..
  Fly   118 -RFGHFDPNLYMLREIYHFSS---MAMEVIALENDYASLAGICEIIDLEGVNSDKMRRFDRVLFR 178

Human   178 FEENY-----PETLKRLFVVKAPK------LFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKH 231
            ...|:     |..:|.::::..||      :|  .||:    ||......|.||..:  |.|::|
  Fly   179 KWWNWLYNCSPLKVKEMYIINMPKDIQGTVMF--LYNV----LSMQVNYPIRVLKNS--EELIEH 235

Human   232 ISPDQVPVEYGGT 244
            |..:.:|.|||||
  Fly   236 IGKESLPEEYGGT 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 16/54 (30%)
SEC14 76..244 CDD:214706 43/194 (22%)
CG10301NP_651173.2 CRAL_TRIO_N 25..71 CDD:215024 15/47 (32%)
CRAL_TRIO 114..248 CDD:279044 35/150 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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