DRSC/TRiP Functional Genomics Resources

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Protein Alignment SEC14L2 and CG33966

DIOPT Version :9

Sequence 1:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens
Sequence 2:NP_001033984.1 Gene:CG33966 / 3885642 FlyBaseID:FBgn0053966 Length:310 Species:Drosophila melanogaster


Alignment Length:342 Identity:73/342 - (21%)
Similarity:127/342 - (37%) Gaps:101/342 - (29%)


- Green bases have known domain annotations that are detailed below.


Human     8 LSPR-QKEALAKFRE---NVQDVLPAL-----------PNPDDYFLLRWLRARSFDLQKSEAML- 56
            |||. ||.|:....|   .:.|.:.||           ...||.||:.:||...|.|:::::.: 
  Fly     7 LSPELQKTAIENLNEVPNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKID 71

Human    57 ------RKHVEFRKQKDID-----NIISWQPPEVIQQYLSGG--------MCGYDLDGCPVWYDI 102
                  .|:.||....::|     .|.......::.:.|:..        |..||    |..|.:
  Fly    72 RFYTLRTKYPEFYLGHNVDVDKALEIFRLGTIVILPRPLNDNGPRLALLRMACYD----PSKYTL 132

Human   103 IGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPA 167
            .....|.||:     |.::   :.|.::.:             |..:..|.|...:...|..:.:
  Fly   133 QEVNRAAGLM-----QQIM---LDEDDVAI-------------VNGLISILDLSNVTTGHFLQMS 176

Human   168 VEAYGEFLCMF-EENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKH 231
             .::.:.:.:| ||..|...:.:..:..|..|...:|:|||.:|:..:.::.|.|:.| |.|...
  Fly   177 -PSFAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKW-EALYNQ 239

Human   232 ISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISR---------G 287
            |....:||||||.                .|.||       ::.||:|..:...|         |
  Fly   240 IPKQYLPVEYGGE----------------NGSIP-------ELLQQWEQRILAYRNYWEEEKNYG 281

Human   288 SSHQ------VEYEILF 298
            :...      |::|.||
  Fly   282 TDESLRVGQPVDFESLF 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 14/66 (21%)
SEC14 76..244 CDD:214706 37/176 (21%)
CG33966NP_001033984.1 CRAL_TRIO_N 30..72 CDD:215024 10/41 (24%)
SEC14 96..252 CDD:238099 38/182 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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