DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SEC14L2 and CG12926

DIOPT Version :9

Sequence 1:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens
Sequence 2:NP_610510.2 Gene:CG12926 / 35996 FlyBaseID:FBgn0033437 Length:313 Species:Drosophila melanogaster


Alignment Length:270 Identity:59/270 - (21%)
Similarity:106/270 - (39%) Gaps:47/270 - (17%)


- Green bases have known domain annotations that are detailed below.


Human     2 SGRVGDLSP----RQKEALAKFRENVQDVLPAL-----------PNPDDYFLLRWLRARSFDLQK 51
            |..:..|||    :..:.|.:..:.:.:.:..|           ...|..||:.:||...:.|:|
  Fly     6 SNSIRSLSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEK 70

Human    52 SEAMLRKHVEFRKQKDIDNIISWQ--PPEVIQQYLSGGMCGYDLD-GCPVWYDIIGPLDAKGLLF 113
            ::..|            ||..:.:  .||:.:..:.|......|| ||.:  .:..||.|.|...
  Fly    71 TKLKL------------DNFYAMRGAVPELYKNRIVGEKQLSILDTGCLL--RLPQPLQADGPRI 121

Human   114 SASKQDLLRTKMRECELLLQECAHQTTKLG----RKVETITI-----IYDCEGLGLKHLWKPAVE 169
            ..|:.....:|    :..:.|.....|.||    |:.:...|     |.|.:|:|..||::....
  Fly   122 HISRYGQYDSK----KYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAV 182

Human   170 AYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISP 234
            ...:...:.::.||...|....|.||.......::.|..:||..||:..:  .:..:.|.|::..
  Fly   183 LVKKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHI--HSKLDSLYKYVPK 245

Human   235 DQVPVEYGGT 244
            :.:|.||||:
  Fly   246 ECLPAEYGGS 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 10/56 (18%)
SEC14 76..244 CDD:214706 42/177 (24%)
CG12926NP_610510.2 CRAL_TRIO_N 32..77 CDD:215024 9/56 (16%)
SEC14 117..254 CDD:238099 31/142 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.