DRSC/TRiP Functional Genomics Resources

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Protein Alignment SEC14L2 and CG3823

DIOPT Version :9

Sequence 1:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens
Sequence 2:NP_572313.1 Gene:CG3823 / 31573 FlyBaseID:FBgn0029863 Length:295 Species:Drosophila melanogaster


Alignment Length:256 Identity:60/256 - (23%)
Similarity:96/256 - (37%) Gaps:43/256 - (16%)


- Green bases have known domain annotations that are detailed below.


Human     1 MSGRVGDLSPRQKEALAKFRENVQDVLPALP----NPDDYFLLRWLRARSFDLQKSEAMLRKHVE 61
            |:.|:.||               ||.|.|.|    |.....|.|:|.....||..::.:|..:..
  Fly    13 MTTRISDL---------------QDWLQAQPQLPQNISRLLLRRFLHTTRGDLSAAQRLLELNYG 62

Human    62 FRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCP---------VWYDIIGPLDAKGLLFSASK 117
            .| .|.....|...|.:...|.|   :...||...|         ::|.:| ..||....|:|:.
  Fly    63 LR-NKHAHIFIDRDPLDASSQQL---LQVADLVPLPGLTPENNKLLFYRLI-DFDADKFNFTAAI 122

Human   118 QDLLRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENY 182
            :..         .::.:|...|....|..:....::|..|..|:||.|.|:.|...::...:|.:
  Fly   123 KVF---------FMVADCRFATENEERLSDGEIPVFDMAGYTLRHLTKTALGALRVYMKFVQEAH 178

Human   183 PETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGG 243
            |..||.:.|:..|........::|||:..:..|.|.....| .:...:|.....:|.||||
  Fly   179 PVRLKEIHVLNCPSYVDKVMAVVKPFIKGEVFKLIHFHLPN-ADTPYRHFPRSMLPEEYGG 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 12/49 (24%)
SEC14 76..244 CDD:214706 41/177 (23%)
CG3823NP_572313.1 SEC14 90..239 CDD:238099 37/160 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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