Protein Alignment ADAT1 and Adar

DIOPT Version :9

• Sequence 1: NP_001311374.1
• Gene: ADAT1 / 23536
• HGNCID: 228
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_001368969.1
• Gene: Adar / 31130
• FlyBaseID: FBgn0026086
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 129/508 - (25%)
• Similarity: 212/508 - (41%)
• Gaps: 148/508 - (29%)

Human     4 ADEIAQLCYEHYGIRLPKKGKPEPNHEWTLLAAVVKIQSPADKACDTPDKPVQVTKEVVSMGTGT 68
            ||.|.:|..|.:...:  ||: |......:||.:|..::.  ..|:.         :|:|:.|||
  Fly   308 ADTIGRLVLEKFMEVI--KGQ-EAYSRRKVLAGIVMTENM--NFCEA---------KVISVSTGT 358

Human    69 KCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQL---AATLKEDSIFVPGTQ-KGVWKLRR 129
            ||:....|..||.:|||||||:::||...:||..||.|   .||..: ||||..|. :..:||:.
  Fly   359 KCVSGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDLQCNQATAYQ-SIFVRNTDGQYPYKLKS 422

Human   130 DLIFVFFSSHTPCGDASIIPMLEFEDQPCCPVFRNWAHNSSVEASSNLEAPGNERKCEDPDSPVT 194
            .:.|..:.:..|||||.|              |....:::.|:...|.:|.|..|
  Fly   423 GVHFHLYINTAPCGDARI--------------FSPHENDTGVDKHPNRKARGQLR---------- 463

Human   195 KKMRLEPGTAAREVTNGAAHHQSFGKQKSGPISPGIHSCDLTVEGLATVTRIAPGSAKVIDVYRT 259
              .::|.|.....|.:                |.||.:.|
  Fly   464 --TKIESGEGTIPVKS----------------SDGIQTWD------------------------- 485

Human   260 GAKCVPGEAGDSGKPGAAFHQVGLLRVKPGRGDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPI 324
                                  |:|     :|.|..:||||||:||||::|.||:||..:: ||:
  Fly   486 ----------------------GVL-----QGQRLLTMSCSDKIARWNIVGIQGSLLSSII-EPV 522

Human   325 YLSAVVIGKCPYSQEAMQRALIGRCQ-NVSALPKGFGVQELKILQSDLLFEQSRSAVQAKRADSP 388
            ||.::|:|...: .|.|.||:.||.: ::..||..:.:.:.::       ....||....:|.:|
  Fly   523 YLHSIVLGSLLH-PEHMYRAVCGRIEKSIQGLPPPYHLNKPRL-------ALVTSAEPRNQAKAP 579

Human   389 GRLVPCGAAISWSAVPEQPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDK 453
                  ...|:|: :.:..|:|.     ...|.:|||...:|  |:|...|..:..|::.:.
  Fly   580 ------NFGINWT-IGDTELEVV-----NSLTGRTIGGQVSR--ITKQAFFVKYGFLMANLP--- 627

Human   454 WPHSLRVQKLDT-YQEYKEAASSYQ----EAWSTLRKQVFGSWIRNPPDYHQF 501
               .:.|:|:.| |.:.|.....||    |.:|..:::..|||::.|.:..:|
  Fly   628 ---GILVRKVTTDYGQTKANVKDYQIAKLELFSAFKREDLGSWLKKPIEQDEF 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADAT1	NP_001311374.1	A_deamin	63..495	CDD:307992	114/441 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..194		4/19 (21%)
Adar	NP_001368969.1	DSRM_STRBP_RED-like_rpt1	105..167	CDD:380694
		DSRM_SF	213..>259	CDD:412133
		ADEAMc	306..677	CDD:214718	128/506 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2777
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820