Protein Alignment TNPO3 and CG10950

DIOPT Version :10

• Sequence 1: NP_001369145.1
• Gene: TNPO3 / 23534
• HGNCID: 17103
• Length: 957
• Species: Homo sapiens
• Sequence 2: NP_611200.2
• Gene: CG10950 / 36942
• FlyBaseID: FBgn0034205
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 73/359 - (20%)
• Similarity: 128/359 - (35%)
• Gaps: 101/359 - (28%)

Human    53 EKTEMQRHYVMYYEMSYGLNIEMHKQT--EIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVT 115
            :||::.       ::...|:|:.||.|  |:.:||.|            |.:
  Fly     5 KKTDLD-------DLKQELDIDYHKITPEELYQRLQT------------HPE------------- 37

Human   116 MTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPP--------VTGSSSGLLALGAL 172
                           ..||||.....:: ...|:.|.||...|        :.|..:.||.:||:
  Fly    38 ---------------NGLSHAKAKENLE-RDGPNALTPPKQTPEWVKFCKNLFGGFALLLWIGAI 86

Human   173 GSQAHLAVKDEKNHHELDHRERESSTNNSVSPSESLRASEKHRGSADYSMEAKKRKAEE--KDSL 235
              ...:|       :.:.....|...::::.....|.|.....|...|..|:|..|..|  |:.:
  Fly    87 --LCFIA-------YSIQASTVEEPADDNLYLGIVLAAVVIVTGIFSYYQESKSSKIMESFKNMV 142

Human   236 SRYDS---DGDK----SDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASS 293
            .::.:   :|:|    ::|||:....|.....|:     |.:..:.:||..|.|     .|..:.
  Fly   143 PQFATVLREGEKLTLRAEDLVIGDVVEVKFGDRI-----PADIRIIEARNFKVD-----NSSLTG 197

Human   294 SSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALR 358
            .|.|.|:..|..|.:...|..| :...|...:....|...:.|..::.|:..|      :||.|.
  Fly   198 ESEPQSRGPDFTHENPLETKNL-AFFSTNAVEGTAKGVVISCGDFTVMGRIAG------LASGLD 255

Human   359 TPITLTSSYPAPFAMMSHHEMNGSLTSPSAYAGL 392
            |..|       |.|...||.:: .:|..:.:.|:
  Fly   256 TGET-------PIAKEIHHFIH-LITGVAVFLGV 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNPO3	NP_001369145.1	IBN_N	33..96	CDD:197981	11/44 (25%)
		Xpo1	121..249	CDD:462459	28/144 (19%)
CG10950	NP_611200.2	IBN_N	25..91	CDD:197981	19/108 (18%)
		Xpo1	103..>207	CDD:462459	25/113 (22%)