DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Igsf9b and dpr3

DIOPT Version :9

Sequence 1:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	59/288 - (20%)
Similarity:	86/288 - (29%)	Gaps:	118/288 - (40%)

- Green bases have known domain annotations that are detailed below.

Mouse   198 TSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQ-DALLTCRAEAY---- 257
            |...||..|     |...:.:...|:..|   |.|....|.|||..... :|::.||.::.
  Fly   212 TDAKRERSG-----AADEESQDADTSQSL---PIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKS 268

Mouse   258 -------------PGNLTYTWYWQDENVYFQNDLKLRVRILIDG---TLIIFRVKPEDAGKYTCV 306
                         .|..|||           :|.:.:|....|.   ||.:.....:|:|.|.|.
  Fly   269 VSWIRKRDLHILTVGTATYT-----------SDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQ 322

Mouse   307 PS-----------NSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPV------DAEP 354
            .:           |.:..||.|.|         |::.||.::...|....:.|.|      |..|
  Fly   323 VNTEPKMSMAFQLNIIEISPDAKA---------VISGPPDLHFKAGSAIILNCLVQQPSVKDIGP 378

Mouse   355 PATVVKWNK-----------DGRP-----------------------------------LQVEKN 373
                :.|.:           ||:|                                   :.:|..
  Fly   379 ----IYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQ 439

Mouse   374 LGWTLMEDGSIRIEEATEEALGTYTCVP 401
            ||.||  ...:||..|.....|.|||.|
  Fly   440 LGDTL--KSRLRISNAQTTDTGNYTCQP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273
		I-set	141..227	CDD:369462	6/28 (21%)
		Ig	231..323	CDD:386229	26/123 (21%)
		Ig	<355..416	CDD:386229	17/93 (18%)
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	20/97 (21%)
		IG_like	243..329	CDD:214653	20/96 (21%)
		Ig	350..464	CDD:299845	22/119 (18%)
		IG_like	<441..477	CDD:214653	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900