Protein Alignment CBX7 and rhi

DIOPT Version :10

• Sequence 1: NP_783640.1
• Gene: CBX7 / 23492
• HGNCID: 1557
• Length: 251
• Species: Homo sapiens
• Sequence 2: NP_536794.1
• Gene: rhi / 44879
• FlyBaseID: FBgn0004400
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 64/274 - (23%)
• Similarity: 104/274 - (37%)
• Gaps: 61/274 - (22%)

Human    11 FAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILD-PRLVMAYE---------------- 58
            :.||.|..||...|:.:.||||.|:|.:.:||||.|::.: .:||..:|
  Fly    24 YVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKSVG 88

Human    59 EKEERDRASG--YRKRGPKPKRLLLQRLYSMDLRSS------HKAKGKE---------------K 100
            :.:....:||  ..:.||...:...|...|:..:::      ::.|||.               |
  Fly    89 KSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIKKTAGKIKDIENYPK 153

Human   101 LCFSLTCPLGSGSPEGVVKAGAPELVD----KGPLVPTL--PFPLRKPRKAHKYLRLSRKKFPPR 159
            .....|..:.:.|.|  |..|.|....    |.|.:.:|  ...|.:|.| .|.:..:..|.||:
  Fly   154 TQMPSTSQVSTDSTE--VFDGNPSATTTNMIKSPRIQSLFSDLNLIEPTK-DKDVGDTSLKTPPK 215

Human   160 GPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEA--DADLAEGPPPWTPALPSSEVTV 222
            ...|.....|.:..|.......:|     ....:||.:...  |:||.|...  :.:||:...|.
  Fly   216 SRRLIEFPQREDAPLSSKHVSPML-----IRKESQPLQSSCTDDSDLGESSS--SMSLPTVSSTS 273

Human   223 TDITANSITVTFRE 236
            ::   .||.||..|
  Fly   274 SE---KSIKVTKSE 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX7	NP_783640.1	CD_Cbx7	7..62	CDD:349293	20/67 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..220		8/31 (26%)
		CBX7_C	209..240	CDD:465385	8/28 (29%)
		Required for cellular lifespan extension	223..236		4/12 (33%)
rhi	NP_536794.1	CD_Rhino	23..73	CDD:349280	19/48 (40%)
		CSD	362..411	CDD:349275