DRSC/TRiP Functional Genomics Resources

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Protein Alignment TRAM1 and TRAM

DIOPT Version :10

Sequence 1:NP_055109.1 Gene:TRAM1 / 23471 HGNCID:20568 Length:374 Species:Homo sapiens
Sequence 2:NP_726710.1 Gene:TRAM / 31042 FlyBaseID:FBgn0040340 Length:368 Species:Drosophila melanogaster


Alignment Length:387 Identity:156/387 - (40%)
Similarity:218/387 - (56%) Gaps:34/387 - (8%)


- Green bases have known domain annotations that are detailed below.


Human     1 MAI-----RKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVT-L 59
            |||     ||.|.|:||:||||||:||||||:|||||||::|||.|.||..:..|::|.:||: .
  Fly     1 MAIKPGLGRKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGE 65

Human    60 PATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQ 124
            ..:.||.......|..||||...:|||.|..||:||:|||::||||::::|.||.|.::||||||
  Fly    66 DPSREQPYGKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQ 130

Human   125 LSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQ--K 187
            |.||||.:.|||..:|:.|.|:.....||..:|.:.|:|..||:::.||||:||..||||||  |
  Fly   131 LVAFYLLSFVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIK 195

Human   188 TKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLF--YFSNEKYQKGF 250
            ||:|..|:.:..|..:.. |..||.|:...|.||||.||||.|.|.|:.:|.  :...|:..|..
  Fly   196 TKEEQQPKIVHSISGFTL-IVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLR 259

Human   251 SLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMWKF 315
            .:...:|.|.|..|.::.|||:.:|:.           |..::||     |..:...|.::::.|
  Fly   260 VVNNAVFFLIRFATSVIGVLTLYYGIG-----------GVRSLLA-----LGGLIALQGYLVFSF 308

Human   316 INFQLRRWREHSAFQAPAVK-----KKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEK 372
            |..|||..||.........|     |||..|.....|:..|:.:  ......:.||..:|.|
  Fly   309 ITEQLRAKREAKKEAKREAKLALQTKKPAKTPKDKVKRKKESDL--PEADQTSPSPIKQKLK 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TRAM1NP_055109.1 TRAM1 50..115 CDD:462460 29/65 (45%)
TLC 117..326 CDD:214789 80/212 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 334..374 11/44 (25%)
TRAMNP_726710.1 TRAM1 52..121 CDD:462460 29/68 (43%)
TLC 124..290 CDD:214789 70/177 (40%)

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