Protein Alignment CBX5 and HP1e

DIOPT Version :10

• Sequence 1: NP_036249.1
• Gene: CBX5 / 23468
• HGNCID: 1555
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_649878.1
• Gene: HP1e / 41108
• FlyBaseID: FBgn0037675
• Length: 174
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 52/168 - (30%)
• Similarity: 86/168 - (51%)
• Gaps: 16/168 - (9%)

Human    10 DSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMK 74
            :|:..|:.|||:||::||||...||::||:||..:|:|.||||...:|||..||...
  Fly    17 NSTDFEETEEYIVERILDRRHYMGQLQYLVKWLDYSDEDNTWESAADLDCHSLIDSI-------- 73

Human    75 EGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFL 139
                    |..:|.||....:|..:....:.|.:....:...|..|...::|:....:.|::.||
  Fly    74 --------ESQKSLKRGQELNNQYETKAKRLKIDPCLVVDSPFNHGFTAQEILKGAKNNGEISFL 130

Human   140 MKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAY 177
            :::...|:..:|.:..|.|:.||:|:.|||....:|.|
  Fly   131 IRFWHLDQPQVVPSGIAYVEIPQMVLKFYENHCNFHDY 168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX5	NP_036249.1	CD_HP1alpha_Cbx5	19..68	CDD:349298	25/48 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..117		6/46 (13%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302	16/56 (29%)
HP1e	NP_649878.1	CD_CSD	27..71	CDD:349274	23/43 (53%)
		CSD_HP1e_insect	111..163	CDD:349337	15/51 (29%)