Protein Alignment CBX5 and swi6

DIOPT Version :10

• Sequence 1: NP_036249.1
• Gene: CBX5 / 23468
• HGNCID: 1555
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_593449.1
• Gene: swi6 / 2541633
• PomBaseID: SPAC664.01C
• Length: 328
• Species: Schizosaccharomyces pombe
• Alignment Length: 268
• Identity: 58/268 - (21%)
• Similarity: 95/268 - (35%)
• Gaps: 100/268 - (37%)

Human     3 KKTKRTA---DSSSSEDEEEYVVEKVLDRRVVK--GQVEYLLKWKGFSE-EHNTWEPEKNLD-CP 60
            ||.|..|   :....|:|:||||||||..|:.:  |..||||||:|:.: ..|||..|.:.. |.
pombe    61 KKLKENAKEEEGGEEEEEDEYVVEKVLKHRMARKGGGYEYLLKWEGYDDPSDNTWSSEADCSGCK 125

Human    61 ELISEFMKKY-------KKMKEGENNKPR--------EKSESNKRKSNFSNSADDIK-------- 102
            :||..:..::       |:.:.....||.        .|::.:|...:.:...:|:.
pombe   126 QLIEAYWNEHGGRPEPSKRKRTARPKKPEAKEPSPKSRKTDEDKHDKDSNEKIEDVNEKTIKFAD 190

Human   103 -----------------------------SKKKREQSNDI------------------------- 113
                                         |:|:..:|.||
pombe   191 KSQEEFNENGPPSGQPNGHIESDNESKSPSQKESNESEDIQIAETPSNVTPKKKPSPEVPKLPDN 255

Human   114 ----ARGFERGLEPEKIIGATDSC-----GDLMFLMKWKD---TDEADLVLAKEANVKCPQIVIA 166
                .:..|.....|.::.:.|:.     |.|...:.||:   :.....:    .|.||||.::.
pombe   256 RELTVKQVENYDSWEDLVSSIDTIERKDDGTLEIYLTWKNGAISHHPSTI----TNKKCPQKMLQ 316

Human   167 FYEERLTW 174
            |||..||:
pombe   317 FYESHLTF 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX5	NP_036249.1	CD_HP1alpha_Cbx5	19..68	CDD:349298	24/52 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..117		11/127 (9%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302	15/64 (23%)
swi6	NP_593449.1	CD_Swi6_like	85..133	CDD:349287	19/47 (40%)
		CSD_Swi6	268..322	CDD:349304	14/57 (25%)