Protein Alignment CBX5 and swi6

DIOPT Version :9

• Sequence 1: NP_001120793.1
• Gene: CBX5 / 23468
• HGNCID: 1555
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_593449.1
• Gene: swi6 / 2541633
• PomBaseID: SPAC664.01c
• Length: 328
• Species: Schizosaccharomyces pombe
• Alignment Length: 268
• Identity: 58/268 - (21%)
• Similarity: 95/268 - (35%)
• Gaps: 100/268 - (37%)

Human     3 KKTKRTA---DSSSSEDEEEYVVEKVLDRRVVK--GQVEYLLKWKGFSE-EHNTWEPEKNLD-CP 60
            ||.|..|   :....|:|:||||||||..|:.:  |..||||||:|:.: ..|||..|.:.. |.
pombe    61 KKLKENAKEEEGGEEEEEDEYVVEKVLKHRMARKGGGYEYLLKWEGYDDPSDNTWSSEADCSGCK 125

Human    61 ELISEFMKKY-------KKMKEGENNKPR--------EKSESNKRKSNFSNSADDIK-------- 102
            :||..:..::       |:.:.....||.        .|::.:|...:.:...:|:.
pombe   126 QLIEAYWNEHGGRPEPSKRKRTARPKKPEAKEPSPKSRKTDEDKHDKDSNEKIEDVNEKTIKFAD 190

Human   103 -----------------------------SKKKREQSNDI------------------------- 113
                                         |:|:..:|.||
pombe   191 KSQEEFNENGPPSGQPNGHIESDNESKSPSQKESNESEDIQIAETPSNVTPKKKPSPEVPKLPDN 255

Human   114 ----ARGFERGLEPEKIIGATDSC-----GDLMFLMKWKD---TDEADLVLAKEANVKCPQIVIA 166
                .:..|.....|.::.:.|:.     |.|...:.||:   :.....:    .|.||||.::.
pombe   256 RELTVKQVENYDSWEDLVSSIDTIERKDDGTLEIYLTWKNGAISHHPSTI----TNKKCPQKMLQ 316

Human   167 FYEERLTW 174
            |||..||:
pombe   317 FYESHLTF 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX5	NP_001120793.1	CD_HP1alpha_Cbx5	19..68	CDD:349298	24/52 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..117		11/127 (9%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302	15/64 (23%)
swi6	NP_593449.1	CHROMO	85..134	CDD:237991	19/48 (40%)
		ChSh	261..326	CDD:197638	17/68 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	48	1.000	Domainoid score	I3903
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870