Protein Alignment GCAT and gcat

DIOPT Version :10

• Sequence 1: XP_016884163.1
• Gene: GCAT / 23464
• HGNCID: 4188
• Length: 521
• Species: Homo sapiens
• Sequence 2: NP_989284.1
• Gene: gcat / 394899
• XenbaseID: XB-GENE-984769
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 329/520 - (63%)
• Similarity: 371/520 - (71%)
• Gaps: 106/520 - (20%)

Human     1 MWPGNAWRAALFWVPRGRRAQSALAQLRGILEGELEGIRGAGTWKSERVITSRQGPHIRVDGVSG 65
            ||.....|:.|    :..|..||:|||||:||.|||.|||||||||||:|||:|||||:|:|..
 Frog     1 MWARCLARSPL----KPGRGLSAVAQLRGVLEKELEAIRGAGTWKSERIITSKQGPHIKVEGKD- 60

Human    66 GPGTVIFPGLPLPHLSCCIHLLSFTSGILNFCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRF 130
                                     :|||||||||||||||||:||:|..:.|||||||||||||
 Frog    61 -------------------------TGILNFCANNYLGLSSHPQVIRAACETLEEFGAGLSSVRF 100

Human   131 ICGTQSIHKNLEAKIARFHQREDAILYPSCYDANAGLFESRALVQPGTETRGPQREAQNTLPLYP 195
            |||||:|||:||.||||||||||||||.||:|||||:||
 Frog   101 ICGTQNIHKSLEQKIARFHQREDAILYISCFDANAGIFE-------------------------- 139

Human   196 EERPGWQYSFLICWSPGQGRSPGWLNDGSTLTASLQALLTPEDAVLSDELNHASIIDGIRLCKAH 260
                                                |||:||||||||||||||||||||||||:
 Frog   140 ------------------------------------ALLSPEDAVLSDELNHASIIDGIRLCKAN 168

Human   261 KYRYRHLDMADLEAKLQEAQKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATG 325
            ||||:|:|:.||||||:|||||||||:||||.||||||||||:|||.||.||.||||:|||||||
 Frog   169 KYRYKHMDLDDLEAKLKEAQKHRLRLIATDGVFSMDGDIAPLREICSLAKRYNALVFIDECHATG 233

Human   326 FLGPTGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAV 390
            |:||.||||||||||||||||:|||||||||||:|||||||.||:.|||||:|||||||:|||||
 Frog   234 FMGPNGRGTDELLGVMDQVTIVNSTLGKALGGAAGGYTTGPKPLIDLLRQRSRPYLFSNTLPPAV 298

Human   391 VGCASKALDLLMGSNTIVQSMAAKTQRCDSQQGRLGGGETWFRSKMEAAGFTISGASHPICPVML 455
            ||.|||||||||.||.|.||:||||:|              ||:||..|||||||..||||||||
 Frog   299 VGSASKALDLLMESNEIAQSVAAKTKR--------------FRTKMTEAGFTISGKDHPICPVML 349

Human   456 GDARLASRMADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGRLHGAL 520
            |||||||.||||:|:|||:|||||:|||||||||||||||..||::|||.||:.|.||||.||.:
 Frog   350 GDARLASLMADDLLQRGIYVIGFSFPVVPKGKARIRVQISTAHSDDDIDNCVQMFTEVGRKHGVI 414

Human   521  520
             Frog   415  414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCAT	XP_016884163.1	AAT_I	27..520	CDD:450240	320/492 (65%)
gcat	NP_989284.1	AAT_I	23..414	CDD:450240	320/492 (65%)