Protein Alignment HEY1 and dpn

DIOPT Version :10

• Sequence 1: NP_001035798.1
• Gene: HEY1 / 23462
• HGNCID: 4880
• Length: 308
• Species: Homo sapiens
• Sequence 2: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 91/316 - (28%)
• Similarity: 137/316 - (43%)
• Gaps: 51/316 - (16%)

Human    10 SSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRR 74
            :||.:.| ......:|...||.:|      :|...|:...||..:.|:|||||.|||:.|:||:.
  Fly     8 NSDDDFD-CSNGYSDSYGSNGRMS------NPNGLSKAELRKTNKPIMEKRRRARINHCLNELKS 65

Human    75 LVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVA 139
            |:..|.:|.....  .|||||:||:|||.||:.:..........:....:.....||.||..||.
  Fly    66 LILEAMKKDPARH--TKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVN 128

Human   140 RYLSIIEGLDASDPLRVRLVSHLNNYASQREA-------ASGAHAGLGHIPWGTVFGHHPHIAHP 197
            ||:|.::|:|..  :|.||.:|||..|:..|.       ::|...||  .| .|.....|....|
  Fly   129 RYVSQMDGIDTG--VRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGL--FP-ATAVTAAPTPLFP 188

Human   198 LLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAP---------PSGSLGPVLPVVTSASK 253
             .|||:.:.|:.|.:|                |||::..         |||....::|...||:.
  Fly   189 -SLPQDLNNNSRTESS----------------APAIQMGGLQLIPSRLPSGEFALIMPNTGSAAP 236

Human   254 LSPPLL--SSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTEIGA 307
            ...|..  .|.|.::|...|.....:.:|..|:..  ||:..:....:|..|.:.|
  Fly   237 PPGPFAWPGSAAGVAAGTASAALASIANPTHLNDY--TQSFRMSAFSKPVNTSVPA 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HEY1	NP_001035798.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		10/41 (24%)
		bHLH_SF	41..126	CDD:469605	31/84 (37%)
		ORANGE	124..170	CDD:128787	18/45 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..238		9/46 (20%)
		YRPW motif	298..301		0/2 (0%)
dpn	NP_476923.1	bHLH-O_hairy_like	39..105	CDD:381483	29/67 (43%)
		ORANGE	114..158	CDD:128787	18/45 (40%)