Protein Alignment ABCA5 and osy

DIOPT Version :10

• Sequence 1: NP_061142.2
• Gene: ABCA5 / 23461
• HGNCID: 35
• Length: 1642
• Species: Homo sapiens
• Sequence 2: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 84/352 - (23%)
• Similarity: 157/352 - (44%)
• Gaps: 32/352 - (9%)

Human  1263 DEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGE 1327
            :.|.|:.|.|..............:.::.|...||.|...|:       ..|....::..|.||.
  Fly    21 NSDLDLAARRRLFISQPSTLATRRQQAVCVRRAHKMYGSSKN-------PNVVLDGLNMTVPKGS 78

Human  1328 ILGLLGPNGAGKSTIINILVGDIEPTSGQVF-LGDYSSETSEDDDSLKCMGYCPQINPLWPDTTL 1391
            |.||||.:|.||:|:::.:||.....||::: ||.............: :||.||...|:.:.|:
  Fly    79 IYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVPGPR-IGYMPQEIALYGEFTM 142

Human  1392 QEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLL 1456
            :|....:|.:..||..|:::....:...|:| .:..|.||.|..|.:|::..|:::|..|::.:|
  Fly   143 RETLIYFGIISAMSKGDIEDRTEFLLKLLNL-PNASKFVKNLSGGQQRRVSLAVALLHEPELLIL 206

Human  1457 DEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK 1521
            |||:.|:||..:|.:|..:....||.....|:||||::|. |....:.::..|::....:..:|:
  Fly   207 DEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLR 270

Human  1522 SKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKL 1586
            .::......::.||               ..:..|..::.. |||....:.:..|.::|.....:
  Fly   271 QQYNADSLEDVFLK---------------LSVLQNMGKRRR-SSIAQEIVEQVTVPAISNPALDM 319

Human  1587 EEAKHAFAI-----EEYSFSQATLEQV 1608
            .:.:||..|     :..|.|.|..:.:
  Fly   320 SDEQHAAEISGEFGDNISMSSAARDPI 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCA5	NP_061142.2	rim_protein	<84..1618	CDD:130324	84/352 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1249..1268		1/4 (25%)
osy	NP_001034071.1	CcmA	50..285	CDD:440746	68/259 (26%)
		YadH	578..773	CDD:440604