Protein Alignment OTP and otp

DIOPT Version :9

• Sequence 1: NP_115485.1
• Gene: OTP / 23440
• HGNCID: 8518
• Length: 325
• Species: Homo sapiens
• Sequence 2: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 142/373 - (38%)
• Similarity: 165/373 - (44%)
• Gaps: 121/373 - (32%)

Human    34 GGSDPGGHP-----------GDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQ 87
            ||...||.|           |.|..||:.:.|..   |......|:                ...
  Fly    50 GGGSSGGVPVGGGVARLHISGGLCDNSNALNGGN---GSSGNGNGN----------------NNN 95

Human    88 GGPNPSQAGQQQGQ----QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRV 148
            |..|.:.:.|||.|    .|||||||||||||||||||.|:||||||||||||:|:|||||||||
  Fly    96 GNGNNNNSMQQQDQHLDKNKQKRHRTRFTPAQLNELERCFSKTHYPDIFMREEIAMRIGLTESRV 160

Human   149 QVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLC--SFHANDTRWAA 211
            ||||||||||||||||||||||.||.|||:.|||  |..|.....||||.||  .....| ||:.
  Fly   161 QVWFQNRRAKWKKRKKTTNVFRTPGALLPSHGLP--PFGANITNIAMGDGLCGTGMFGGD-RWSV 222

Human   212 AAMP---GVSQL----PLPPAL----------------GRQQ-----AMAQS------------- 235
            ...|   |..||    ||..:|                |..|     |:..|
  Fly   223 GVNPMTAGFGQLNQSSPLSSSLNSGLNSGINMGSALGAGSYQHYGLNALGDSMMYQHSVGGVSCG 287

Human   236 ------------LSQCSLAAGPPPNSMGLSNSLAGSNGAGL----------------QSHLYQPA 272
                        ::.|| :..|||.|...::|....||..:                |:|.:.|.
  Fly   288 PSGSPSATTPPNMNSCS-SVTPPPLSAQPNSSQNELNGEPMPLHQQQQQQTHQHQQQQTHQHHPM 351

Human   273 FPGMVPASLPGPSNVSGS-PQLCSSPDSSDVWRGT--SIASLRRKALE 317
            .|       |.|:..... ||...||  ||....|  |||:|||:|.|
  Fly   352 AP-------PTPTQQQQQLPQSMQSP--SDGANDTLHSIAALRRRASE 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OTP	NP_115485.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..112		26/92 (28%)
		Homeobox	107..156	CDD:395001	44/48 (92%)
		OAR	303..320	CDD:397759	9/17 (53%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319		9/14 (64%)
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	43/47 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I6013
eggNOG	1	0.900	-	-		E33208_3BA7E
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1243020at2759
OrthoFinder	1	1.000	-	-		FOG0007109
OrthoInspector	1	1.000	-	-		oto91802
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46770
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4709
SonicParanoid	1	1.000	-	-		X5198
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.910