Protein Alignment EXOSC2 and RRP4

DIOPT Version :10

• Sequence 1: NP_055100.2
• Gene: EXOSC2 / 23404
• HGNCID: 17097
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_011936.1
• Gene: RRP4 / 856466
• SGDID: S000001111
• Length: 359
• Species: Saccharomyces cerevisiae
• Alignment Length: 296
• Identity: 123/296 - (41%)
• Similarity: 169/296 - (57%)
• Gaps: 36/296 - (12%)

Human    21 DTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVV 85
            ::...:|.||:.:|.|..:|||||||..:....:||||:|.|||:|:.|..||.||..|.||.||
Yeast    49 ESDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETGDHVV 113

Human    86 GRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFS 150
            |||.||..|||||:...:..:||:|.|:|||||.|||:|..|||.||.||:||||::||||::|.
Yeast   114 GRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLLNAEVQSLFQ 178

Human   151 DGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPE----- 210
            ||:.||||||||||||..|:..||..||:.|.|.|.|:||...:|:||.||:||:..|.:
Yeast   179 DGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNGYIWLRKTSQMDLAR 243

Human   211 ---------------------------HKEEEAGGFI---ANLEPVSLADREVISRLRNCIISLV 245
                                       ..|||:...|   .|...:|...|:.|.|..|.|.:|.
Yeast   244 DTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPSISNNIRQAICRYANVIKALA 308

Human   246 TQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280
            ...:.:....|:..||||:.: .:.::::..:||.|
Yeast   309 FCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESI 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC2	NP_055100.2	ECR1_N	26..63	CDD:464162	17/36 (47%)
		S1_Rrp4	75..166	CDD:240215	58/90 (64%)
		KH-I_Rrp4_eukar	169..285	CDD:411953	39/148 (26%)
RRP4	NP_011936.1	ECR1_N	54..91	CDD:464162	17/36 (47%)
		S1_Rrp4	103..194	CDD:240215	58/90 (64%)
		KH-I_Rrp4_eukar	197..345	CDD:411953	39/148 (26%)