Protein Alignment EXOSC2 and Rrp40

DIOPT Version :10

• Sequence 1: NP_055100.2
• Gene: EXOSC2 / 23404
• HGNCID: 17097
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_722725.1
• Gene: Rrp40 / 319033
• FlyBaseID: FBgn0260648
• Length: 232
• Species: Drosophila melanogaster
• Alignment Length: 203
• Identity: 45/203 - (22%)
• Similarity: 81/203 - (39%)
• Gaps: 39/203 - (19%)

Human    26 LVVPGDTITTDTGFMRGHGTYMG------EEKLIASVAGSVERVNK-LICVKALKTRYIGEVGDI 83
            :|:||:.|.......:.....:|      ::.::||.||.:..... ...|...:.|||...||:
  Fly     7 IVMPGERIAAIEELAKSKRVILGPGLRRLDDTVVASKAGPLRHKEPGTFWVDNYQRRYIPARGDL 71

Human    84 VVGRITEVQQKRWKVE---TNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEV 145
            ::|.:.......::|:   |::...|.|...:.:       :::..|       |..||||.|.|
  Fly    72 ILGIVRAKAGDLYRVDIGATDTASISYLAFEAAS-------KKNRPD-------LIPGDLIYARV 122

Human   146 QAVFSD-----GAVSLHTRSLKYGKLGQGVLVQVSPSL---VKRQKTHF-----HDLPCGASVIL 197
            ....:|     ..|:...:|.|.|.|..|...:.|.:|   :.|:....     .:||  ..:.:
  Fly   123 LNASADIEPELVCVNSVGKSGKLGVLTDGFFFKCSLNLGRMLLRENCPVLAALTRELP--YEIAV 185

Human   198 GNNGFIWI 205
            |.||.||:
  Fly   186 GVNGRIWL 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC2	NP_055100.2	ECR1_N	26..63	CDD:464162	9/42 (21%)
		S1_Rrp4	75..166	CDD:240215	23/98 (23%)
		KH-I_Rrp4_eukar	169..285	CDD:411953	11/45 (24%)
Rrp40	NP_722725.1	Rrp40_N	23..63	CDD:436400	6/39 (15%)
		S1_Rrp40	63..148	CDD:240216	23/98 (23%)
		KH-I_Rrp40	150..226	CDD:411954	11/46 (24%)