DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZDHHC17 and CG18810

DIOPT Version :9

Sequence 1:NP_056151.2 Gene:ZDHHC17 / 23390 HGNCID:18412 Length:632 Species:Homo sapiens
Sequence 2:NP_652670.2 Gene:CG18810 / 59171 FlyBaseID:FBgn0042133 Length:300 Species:Drosophila melanogaster


Alignment Length:230 Identity:51/230 - (22%)
Similarity:81/230 - (35%) Gaps:78/230 - (33%)


- Green bases have known domain annotations that are detailed below.


Human   439 CSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISY 503
            |..|.|..|.||:||..|..|:...||||.:.|.|:|..|:|||   .:||:            |
  Fly    99 CDKCGILAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYF---FYFLI------------Y 148

Human   504 WGLHCETTYTKDGFWTYI-----------TQIATCS---------------PWMFWMFLNSVFHF 542
            :.|.|..:.|....:.|:           |..|..|               |.::.:....||..
  Fly   149 FFLSCMISLTSSSIFIYVLHGGRYQLFMLTHPAPNSAYFNSLIIRIIYFKLPDIYELVFTLVFVL 213

Human   543 MWVAVLL-------------MCQMYQISCLGITTNERMNARRY--KHFKVTTTS--IESPFNHGC 590
            :|:.|.:             .|..:::..:......|.|.:.:  :..|.|..|  :.|..:|  
  Fly   214 LWIGVCVATYVAYDQWSRGYFCYDFELQNIPFDRKLRRNFKTFLGRRMKWTWISGFVPSQLDH-- 276

Human   591 VRNIIDFFEF-----RCCGLFRPVIVDWTRQYTIE 620
                 |.|:.     |        :.||..:.||:
  Fly   277 -----DGFDLDPDNER--------VADWCSETTIK 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZDHHC17NP_056151.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000250|UniProtKB:Q80TN5 11..305
ANK repeat 89..120 CDD:293786
Ank_2 94..187 CDD:403870
ANK repeat 122..154 CDD:293786
ANK repeat 156..187 CDD:293786
Ank_2 161..255 CDD:403870
ANK repeat 189..221 CDD:293786
ANK repeat 224..255 CDD:293786
Ank_2 229..>286 CDD:423045
DHHC 438..568 CDD:396215 38/167 (23%)
CG18810NP_652670.2 zf-DHHC 92..>138 CDD:303066 17/38 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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