DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZDHHC17 and CG4676

DIOPT Version :9

Sequence 1:NP_056151.2 Gene:ZDHHC17 / 23390 HGNCID:18412 Length:632 Species:Homo sapiens
Sequence 2:NP_610853.1 Gene:CG4676 / 36465 FlyBaseID:FBgn0033815 Length:284 Species:Drosophila melanogaster


Alignment Length:234 Identity:60/234 - (25%)
Similarity:92/234 - (39%) Gaps:46/234 - (19%)


- Green bases have known domain annotations that are detailed below.


Human   358 LPLGIYLATKFWMYVT------------WFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDP 410
            |.:.:::...:..:||            |:...|  |..||:.....:|.:|...       .|.
  Fly    22 LLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLW--LASLFLIFNITSNMLACML-------VDT 77

Human   411 GIIKATEEQKKKTI--VELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNC 473
            .|.|   |..|..:  .:||...|      |..|....|.||.||.|||.|:.|.||||.:...|
  Fly    78 SIRK---ELLKPPLDAAQLARWHS------CQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCC 133

Human   474 VGAGNHRYFMGYLFFLLF-MICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLN 537
            :|..|:|||..||.:::. .:...|...|..|.||.      |.:|.:.|.....:|.:..|...
  Fly   134 IGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHL------DIYWRWSTLFTIFAPVVSLMLSP 192

Human   538 SVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFK 576
            |     |.:..|:  :|.::.||...:..:....:..||
  Fly   193 S-----WESFYLV--IYDLTLLGFAISSLLLVFHWSIFK 224

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZDHHC17NP_056151.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000250|UniProtKB:Q80TN5 11..305
ANK repeat 89..120 CDD:293786
Ank_2 94..187 CDD:403870
ANK repeat 122..154 CDD:293786
ANK repeat 156..187 CDD:293786
Ank_2 161..255 CDD:403870
ANK repeat 189..221 CDD:293786
ANK repeat 224..255 CDD:293786
Ank_2 229..>286 CDD:423045
DHHC 438..568 CDD:396215 40/130 (31%)
CG4676NP_610853.1 zf-DHHC 99..232 CDD:279823 42/139 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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