DRSC/TRiP Functional Genomics Resources

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Protein Alignment PSD3 and GEA1

DIOPT Version :10

Sequence 1:NP_001399795.1 Gene:PSD3 / 23362 HGNCID:19093 Length:1175 Species:Homo sapiens
Sequence 2:NP_012565.1 Gene:GEA1 / 853488 SGDID:S000003792 Length:1408 Species:Saccharomyces cerevisiae


Alignment Length:271 Identity:64/271 - (23%)
Similarity:102/271 - (37%) Gaps:94/271 - (34%)


- Green bases have known domain annotations that are detailed below.


Human   684 EAAKRLAKRLYQ---LDRFKRSDVAKHLGKNN-EFSK-------------LVAEEYLKFFDFTGM 731
            |.||:..:.|.:   :|.....|:|..|..|| ..:|             .:.:|::..|||.|:
Yeast   554 EKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGL 618

Human   732 TLDQSLRYFFKAFSLVGETQERERVLIHFSNRY-----------------------------FYC 767
            .:|:::|.....|.|.||:|:.||::..||::|                             .:.
Yeast   619 RVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHV 683

Human   768 NPDTIASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKVKLSQFF 832
            .||.    |.|..|:.:|::||||.|...:...||..::..||:|...|.||.:..|.       
Yeast   684 QPDA----DSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLH------- 737

Human   833 SSLVFGHHYFRISTCSSALAALYNSIK------------NEKLEWAVDD-EEKKKSPSESTEEKA 884
                                .:|.|||            ||:  |..|. .....|.|..||.:.
Yeast   738 --------------------KIYTSIKVKEIVMPEEHHGNER--WFEDAWNNLISSTSVMTEMQR 780

Human   885 NGTHPKTISRI 895
            :.|:|  ||::
Yeast   781 DFTNP--ISKL 789

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSD3NP_001399795.1 Sec7 682..863 CDD:238100 54/236 (23%)
PH_EFA6 908..1033 CDD:270107
GEA1NP_012565.1 Sec7_N 328..471 CDD:463703
Sec7 541..748 CDD:460178 52/224 (23%)
Blue background indicates that the domain is not in the aligned region.

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