Protein Alignment ANGEL1 and CG31759

DIOPT Version :10

• Sequence 1: NP_001357675.1
• Gene: ANGEL1 / 23357
• HGNCID: 19961
• Length: 744
• Species: Homo sapiens
• Sequence 2: NP_723735.2
• Gene: CG31759 / 326158
• FlyBaseID: FBgn0051759
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 96/463 - (20%)
• Similarity: 185/463 - (39%)
• Gaps: 78/463 - (16%)

Human    55 EECEGLLQQWREEGLSQVLSTASEGPLIDKGLAQSSLALLMDNPGEE--NAASEDRWSSRQLSDL 117
            |..:.:|.:.:...:.::..:..:..:  |..|:.::.||.|..||:  ....||...::.:|::
  Fly    40 EPIDAILARIQSNIIGRLAKSCKKSKI--KPPAEINVKLLSDKYGEKFNELTFEDLVVTQDISNV 102

Human   118 RAAENLDEPFPEMLGEEPLLEVEGVEGSMWAA-------IPMQ-SEPQYADCAALPVGALATEQW 174
            : .:.||..:..:.....:..::.:...:.|.       :.:| .|.|::..............|
  Fly   103 K-LQVLDTVYDLVFNPPWISSLKFLPSCILAGFVIYPTNVQIQFGERQFSKAVWFKAKKPTDTDW 166

Human   175 EEDPAVLAWSIAPEPVPQE-EASIWPFEGLGQLQPPAVEI------------PYHEILWREWEDF 226
            |.......:.:.||.:... :..:.|...||...|...:|            |:.:   |:....
  Fly   167 EVCGEGFQYLVTPEDIGYHLKFVVTPGNALGMTGPVVEKITNSAVQESPGRCPFQD---RQRHTT 228

Human   227 STQPDAQGLKAGDGPQFQFTLMSYNILAQDLMQQS----SELYLHCHPDILNWNYRFVNLMQEFQ 287
            ::..::..::          ::|||:|| ||...|    |.|:.:|....|..:||....:.|..
  Fly   229 NSLSESNEIR----------VVSYNLLA-DLYASSDYAGSTLFSYCPAKYLQIDYRKPLFINEII 282

Human   288 HWDPDILCLQEVQE---DHYWEQL--EPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCAS 347
            .::.||||||||.:   |...:::  :|.....|...    ..|...:|.|:.::.:||.||.:.
  Fly   283 GYNSDILCLQEVDQRIFDFDLKEILEQPPYNYHGIMA----PKGKCAEGVAIFFRNSRFDLLDSQ 343

Human   348 PVEYFR--PGL----ELLNRDNVGLVL---------LLQPLVPEGLGQVSVAPLCVANTHILYNP 397
            .:....  |.|    .|.|:..|...|         .||..:....|..:.  :.|||||:.::|
  Fly   344 ILHLGSNIPALPVFESLWNKIKVNAQLAERICERSTTLQTCLLRIKGTDNY--VLVANTHLYFHP 406

Human   398 RRGDVKLAQMAILLAEVD-------KVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYHG 455
            ....::|.||...:..|:       |...:|...:..:|.|||.||||:..:|..:.: :|....
  Fly   407 DADHIRLLQMGFSMLFVEQSISKAIKDFNISSHKNIGLIFCGDFNSVPECGIYKLMTE-QLAEKT 470

Human   456 MPAWKSLA 463
            :..|:|.|
  Fly   471 LEDWQSNA 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ANGEL1	NP_001357675.1	EEP	248..>449	CDD:469791	63/231 (27%)
CG31759	NP_723735.2	EEP	239..561	CDD:469791	67/248 (27%)