|
Human 60 GADTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILHHEKQYEPFYSSFVALSTH--- 121
|.| |...|:.|:.....|....|:..|:.::...|.:....|..:..||::|.||:..
Fly 7 GTD----WNSVVKALILNRTGALNKNEVVNLLKAITRCEHDFFEEESNFTQFYTAFAALAADKLM 67
Human 122 YITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTG--CSRLDRT 184
.|.|:| :.|:..:..|..|||.|.:.|| ........|.|:..:|.||.| |.....:
Fly 68 QIKTIC----QTQICQLHDATAVLIRFIIYRL---PRVSVYETKWLLGALKMLCEGRECPASASS 125
Human 185 EIITFTA---MMKSAKLPQ-TVKTL--------SDVEDQKELASPVSPELRQKEVQMN--FLNQL 235
.:..:.| ::||.|.|: |.|:: |...:.|| ||.| |:::....:: .|.||
Fly 126 SMFDYNAVANVLKSCKHPESTTKSIMPSSSSSGSGASNDKE--SPKS-EIKRSRSDLSSVILQQL 187
Human 236 TSVFNPRTVASQPISTQTLVEGENDEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLN 300
.:...|..:...|:|.:. ||....| :|.||...||..|.:.||.||::
Fly 188 IAPLEPGKMTWVPLSEEV-----------TDCTEQI------LAANVEYFQEQNGVDTLLDVCVS 235
Human 301 LPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQ 365
||...||.:::.:.:.......:|.|..:||||::..:.::.|:|:.....:|..::||.|||::
Fly 236 LPILNRYRSKYMETINGGKSLYLPLTQVEATAVKSSMNHMLTDLTILSQAQALIEMQPLTPSRIE 300
Human 366 DVTVLSLSCLYAGV--SVATCMAILHVGSAQQVRTGSTS--------------SKEDDYESDAAT 414
.:::..::.||..| |:||.:..:...|:.|.:|.||| ...||:|..|.:
Fly 301 RLSMCGIAALYNAVLTSIATSVLGMSQASSSQKQTASTSQGSGVGGSSGGQSNKDHDDFEDQACS 365
Human 415 IVQKCLEIYDMIGQAISSSRRAGGEH-YQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLA 478
||.|.||||..||....:|.|. | |||....|:|.|::.:...:..|.:. |...|..:
Fly 366 IVNKALEIYSNIGHMFKTSARI---HVYQNHLCYGSWLLISGIQGAMGASGSG----GSSSDSAS 423
Human 479 ALRVRDILSRTKEG--VGSPKLGP------GKGHQGFGVLSVILANHAIKLLTSLFQDLQVEAL- 534
:.....||.| .|:....| .|..||||.|:..:|||:||||:.|.:||:|||.
Fly 424 ----KSASKATKSGSEAGTAPTTPIARVNLFKVQQGFGELNAAIANHSIKLLSELIEDLKVEAAC 484
Human 535 -HKGWETDGP-PAALSIMAQSTSIQRIQRLIDSVPLMNLLLTLLSTSYRKACVLQR-QRKGSMSS 596
.....|:.| ||...|:...:|::||.|::::..|..|...|.:.:|||||.|:| ..|.....
Fly 485 GQSLESTELPEPAQFDILQNYSSLERIVRVLNTATLHQLFTFLATVAYRKACTLKRASAKDRTEC 549
Human 597 DASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETISPSKEKAAPPPPPPPPPLESSPRV 661
:..:.:||.||:.|..|.: |:|::||||..||.||:||:|| |:....
Fly 550 EPISYSDSTTYFNDSLSCS--DNSEEDDSESYLGHWFKETLSP----------------ETHDDN 596
Human 662 KSPSKQAPGEKGNILASRKD-PELFLGLASNILNFITSSMLNSRNNFIRNYLSVSLSEHHMATLA 725
.:.|.|...|:.:.|..:.| |..:|.||::|..|:...:.| |:.:::.|:...:|:..|..:|
Fly 597 ANTSTQERAEQKSALVPKLDEPHEYLDLAADIFCFLDQFLAN-RHAYMQRYVKAGVSDQQMLLMA 660
Human 726 SIIKEVDKDGLKGSSDE---------------------------EFAAALYHFNHSLVTSDLQSP 763
:|||:.|:|.::..||: .|:.|...:.|:|:::.|.|.
Fly 661 NIIKDFDRDVMRNESDQGSGNAPAASAGAGTSAGASTKWQTSMIRFSGAAGRYIHNLISTSLLSE 725
Human 764 NLQNTLLQQLGVAPFS--EGPWPLYIHPQSLSVLSRLLLI--WQHKASAQGDPDVPECLKVWDRF 824
.||:.|||.|.::|:| ...|||.::|.:||||.::||: .|.|.:| ||.||.|.
Fly 726 QLQSNLLQHLSISPWSTDTNTWPLQVYPSTLSVLVQILLLKPTQEKEAA--------CLSVWHRL 782
Human 825 LSTMKQNALQGVVPSET------EDLNVEHLQMLLLIFHNFTETGRRAILSL-------FVQIIQ 876
::|: ::||..|.| ||||:||.|:||.:||:.....:::||.| ..::.:
Fly 783 INTL----VEGVCSSNTASDSDYEDLNIEHAQLLLFLFHSLNLMQKKSILLLTAGGVIRCAEVCR 843
Human 877 ELSVNMDAQMRFVPLILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDS----- 936
.:|.:...:...: ::|:||||..:||:.....||..|.:||:.||.| .|...|:
Fly 844 GISEDRPVKNSQI-MLLSRLLLFLEYLMKHLYNAPPELLDQVRWNLFS-----VSSMPDTQKITD 902
Human 937 --NSR-RATTPLYHGFKEVEENWSK---HFSSDAVPHPRFYCVL--SPE----ASEDDLNRLDSV 989
|.| :..:...| ::|||:.| .:.|.. .|.||.:: .|| |.| .:||.:
Fly 903 LLNCRTKLNSYCRH---DIEENFRKSAGEYGSSI--RPTFYSLVMGDPEISYWAQE---FKLDGL 959
Human 990 ACDVLF---SKLVKYDELYAALTALLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRI-LGI 1050
|.:.:. .|| ||..|..|||.:|:. :.:....::::|..:....||:||.|.|.|:: ||
Fly 960 AWNFILCTPDKL-KYPLLVDALTDILSI-TDMSMYSKEKDKEASMHNLCAIQYCFTIAWKLNLG- 1021
Human 1051 LPPSKTYINQL-SMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHASSLLELAS 1114
||||.:::..| :..||. ||:|.||.||.::|....:...||||||..::|.:|
Fly 1022 LPPSTSHVESLKAERSPN------LHSLMWSIRLPLASSHYLVVSSLIKQGMYTQYAETL----- 1075
Human 1115 TTKCSSVKYDVEIVEEYFARQISSFCSIDCTTILQLHEI---------PSLQSIYTLDAAISKVQ 1170
.|....:..|: :|..:| |||.:... |.|..:...|:.::.:|
Fly 1076 WTHVGDIGADI----KYSLKQ----------TILGVEAFNSQMNGNGTPRLSDLILFDSLVAHMQ 1126
Human 1171 V-------------------------------------------SLDEHFSKMAAETDPHKSSEI 1192
. |:|: .|:..:.|...||::
Fly 1127 AVAWANKEGLKWPRKESEDAAGEQSAGTSLTSSSNDPELYSSNESIDD--QKLKQDDDGKLSSDL 1189
Human 1193 TK-NLLPATL--QLIDTY---ASFTRAYLLQNFNEEGTTEKPSKEKLQGFAAVLAIGSSRCKANT 1251
.| |.|...| :|:::| :...|..:|:..: ..|.|| ....::.|.|.:
Fly 1190 QKYNQLVNELMVKLMNSYQLLSVIVRGQMLKQLS-SSTPEK-------ALNLIVPIVSDK----- 1241
Human 1252 LGPTLVQNLPSSV---------QTVCESWNN-INTNEFPNIGSWRNAFANDTIPSESYISAVQAA 1306
|.::..|.::. |.:...|.. :..|:| ||.....|.|.||..|..|
Fly 1242 --PAIMLELHAAFLKLLPNEDKQLIANEWPKCLMVNDF--------AFNGKQHPVEPYILNVIDA 1296
Human 1307 HLGTLC-SQSLPLAASLKHTLLSLVRLTGDLIVWSDEMN---PPQVIRTLLPLLLESSTESVAEI 1367
|:..|. ..:.....:|||.|.|:::|. :|::.....| ..|:.:.|:..:|:..|:.:...
Fly 1297 HIIELTRGSNYSTLHTLKHCLKSILQLF-ELLLPHRTANAEVETQLKQLLISSMLDMRTDYLQGH 1360
Human 1368 SSNSLERILGPAESDEFLARVYEKLITGCYNIL---------ANHADPNSG---------LDESI 1414
|.:.|..||.....:.....:||.::..||.:| ...|.|:.| .:||:
Fly 1361 SEHCLREILSGLTQEAQKLLLYEHMVGYCYRMLKEFAADLRQPQSAGPSGGAPLDQDRAMFNESM 1425
Human 1415 LEECLQYLEKQLESSQARKAMEEFFSD--SGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTE 1477
|...|:.:.|.||...|.:||.:||.| ||.|..::::....:|...:..::|:|..:||||:.
Fly 1426 LFAVLKTMFKMLEKPVAVQAMRQFFKDQRSGSLTTLLLSFTGTSLPVSYARKMLQFVNRLFQLSL 1490
Human 1478 KSPNPSLLH--LCGSLAQLACVEPVRLQAWL----------------------TRMTTS------ 1512
:: :....| |....::||.|:..||:.|| .||.||
Fly 1491 QA-DSQFQHEDLVECFSELATVDVARLKQWLGHIIYGPNVSTDVSTSEALDTTCRMLTSILQPSS 1554
Human 1513 -----------------PPKDSDQLDVI------------------------------------- 1523
.|..|||||.:
Fly 1555 SSSSNAQTPTNMATVSAMPSISDQLDPMEIEYDCGTAAGGGESNPGTGGAAANTSQILSLWQAAQ 1619
Human 1524 ----------------QENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLTPMATEMLA-NGDGTG 1571
:.|..||......:|::.|:..: :...|...|..:...::: ..:|..
Fly 1620 PNPSEESSQACDHSDSERNGALLLSFVKSLVKDQSKASQ-IAPPLFQALLQLGQTLISPPQEGCD 1683
Human 1572 FPELMVVMATLASAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMILECTCH 1636
|.:::.:|.|||.|....||:.|.|..:.||...|..|..| |.||. |....
Fly 1684 FADVLQIMITLADASPARGHVALFNTTLLWLELAKLQLPDK-----------HLKHA---ENVSA 1734
Human 1637 IMSYLADVTNALS-----QSNGQGPSHLSVDGEERAIEVDSDWVEELAVE-EEDSQAEDSDEDSL 1695
.:.||:::..::. |.|......|..|.:| ..:|||.| |:||..:|||||:|
Fly 1735 QLRYLSELLQSIGFRGSRQHNPPWDDELQTDIDE--------LYDELAEEGEQDSLLDDSDEDTL 1791
Human 1696 CNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDG 1760
.||||||:.||||||||||||||||.|::.||||:|||:||||.|::||||||:|||||||||||
Fly 1792 NNKLCTFSQTQKEFMNQHWYHCHTCNMINTVGVCSVCARVCHKGHDVSYAKYGNFFCDCGAKEDG 1856
Human 1761 SCLALVKRTPSSGMSSTMKESAFQSEPRISESLVRHAS-------TSSPADKAKVTISDGKVADE 1818
||.||.:|.. |:.:::|| .|...|..|.| :|.|..:..:|..|....:
Fly 1857 SCQALSRRIG----SNEVRDSA-----GIGSYLPSHMSLLAGKKRSSLPVGQPVLTRKDSLTNE- 1911
Human 1819 EKPKKSSLCRTVEGCREELQNQANFSF-APLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALSE 1882
:.:.|.:.:|..||.||:|..:.. ...:|:..:.|:.:|..|....|.||...||..||..
Fly 1912 ---RIAVLTKLLEPYRETLQHQDQWLLVVRCILEYFDLLLPSINENCMLYSIVGCHKRATAALER 1973
Human 1883 LHTVEKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRR 1947
||.:|::.::|||||..||||||||||||||||||||||||:.|:|:.|:||||.|.||||||||
Fly 1974 LHLLEQSFQVTDQLMFATLGSQEGAFENVRMNYSGDQGQTIKHLLSSGVVRRVAFCCLSSPHGRR 2038
Human 1948 QHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKD 2012
|.|||||||||:|:|||||||||||:||||||||:|:|||:..||:||..|||.||.|||||||:
Fly 2039 QQLAVSHEKGKVTILQLSALLKQADASKRKLTLTQLSSAPIACTVISLAANPCNEDCLAVCGLKE 2103
Human 2013 CHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLCVDALSPTFYF 2077
||:||||||||.::|:|::|||..||:|.||||||||||.||:||:|:||||||.||..||.:|:
Fly 2104 CHILTFSSSGSTNEHIVVNPQLENGNYIKKAVWLPGSQTLLAVVTSDYVKIYDLAVDTYSPKYYY 2168
Human 2078 LLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLKQDSN 2142
|:...||||.||::.:...|::...|| ||||||.:::.|.|..|.|||||.||::|:.:| |..
Fly 2169 LVAVGKIRDCTFVYQDGNYNMLTFASS-GYIYTQQLDQQSLAVHGDFYVTNTLELSHQHIK-DIA 2231
Human 2143 SQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRTTLEVLQLFPINIKSFVVCSSNGGSKTSPA 2207
..:.|||||:||||.||:||:||..|:||.:.::..:..|..::.::..|....:|.|..: .
Fly 2232 GHIGGGGVSIYYSHTLQLLFYSYSCGRSFFSPLTNVSEGVKGIYHLDTNSASKSASKGPLQ---P 2293
Human 2208 LCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRT 2272
|.||:||..|||||....||:..|:::|:.|:...:||||...||::|.|:|.|||.... .::|
Fly 2294 LVQWTEVTGHPGLVYASMQTSNNPIILMITPERIYLQEIKAQSAKSRIMDVVGIRHAVAG-VEKT 2357
Human 2273 TMILLCEDGSLRIYMANVENTSYWLQPSLQP------SSVI--------SIMKPVRKRKTATITT 2323
|::||||||||||:.|..|.||:||.|.:|| ||.: |..|......:..:|:
Fly 2358 TLLLLCEDGSLRIFSAQPEYTSFWLSPQVQPFGNQLYSSTLMAKGGGSGSTSKSKSNTASGKMTS 2422
Human 2324 RTSS----------QVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPG 2378
|.:| |..||||||||...|.|||||||||||:||.|::|.||.||||:||:|:..
Fly 2423 RKASQQQKQPTAGGQPVFPIDFFEHCNMLADVEFGGNDLLQIYNKQKLKTRLFSTGMFVASTRSN 2487
Human 2379 GFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADK 2443
|||:|:.||:..:|:.|:|:.||||.::|||..:.|.|||:...:.|:||||.|.||||.||:||
Fly 2488 GFTLEVINNDPNVVIVGIRVLIGTQDVQRAPQSVTILGRTIPTPVRRARWFDIPLTREEMLQSDK 2552
Human 2444 KLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPE-EFPSASVSNICPSNLNQSN-GTGDS 2506
.|.:....:.||..||::|.:::|||:||..|||||..: ..|.:|...:..|..:.:| |.|
Fly 2553 LLKVVFAKAPDPEHVTLLDCIEVYGKSKELVGWPDESEDVTVPGSSAPAVSSSQASSANFGEG-- 2615
Human 2507 DSAAPTTTSGTVLESSETESLTKLDRLVVSSLEALE-SCFAVGPIIEKERNKNAAQELATLLLSL 2570
...:|:|||:....||.:: :...:|..:.....:.|.:..:.||| |
Fly 2616 -----------------FNCITQLDRMANHLLEVMDCALHLLGSGVPASMRQKAVKTASALLL-L 2662
Human 2571 PAPASVQQQSKSLLASLHTSRSAYHSHKDQALL---SKAVQCLNTSSKE---GKDLDPEVFQRLV 2629
|.|..||.|::.:||:|:.:|:.||::||..|| ::.:|.:....:: .:::|||.|.|||
Fly 2663 PTPNPVQTQARYVLATLYGTRALYHNYKDGVLLQFVNRELQSMQPKLEKLETLREIDPEAFYRLV 2727
Human 2630 ITARSIAIMRPNNLVHFTESKLPQMETDCFFPRCACWSLGIVGILIGAPLE----TPSPEGMDEG 2690
:..|.||..||.:|... |...:..||..|:|..|| ||: :||
Fly 2728 LMVRGIANARPQSLAKI----------------CVENNYDIVPTLMGIVLELHKVTPT---LDE- 2772
Human 2691 KEPQKQLEGDCCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCEL 2755
|.|......|.| |..|:.||:|::|:...:.
Fly 2773 -----------------------------PVNIVKRGLCQP-----ETIVHCLVEIMYGFALADP 2803
Human 2756 DCINTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDA 2820
..:...:|.::.:|......:|.|.|:|||.:|.||.|||.|.:.:.|..:|| ..:
Fly 2804 GQVGRMTKYFIDLLKHDASVISHSAKEALILLLSPRMKRRKVAIVTPPACSTP---------TPS 2859
Human 2821 DEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGN-PSP------------ 2872
...||:. |:.......:::.|:..:....:|..|. |.|
Fly 2860 TSTMQAL--------------QAAASSAASDIIEEAAGVVVDGSVGGGGLPEPNADAEGAAVGVG 2910
Human 2873 ---------LEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSAL-----GLQS 2923
|||.:.| |||.:|.:|.|||||.::::||||||| |.|..::|| ||.:
Fly 2911 GVGQQQMLNLEAFMGG--GFPRLLGLPEDADDEAIMDIAIALSLQ--QHGGDANALQSLQQGLAN 2971
Human 2924 LGLSGQAPSSSSLDAGTLSDTTASALVTLSAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGG 2988
|....||.:.::. ..|:|.|:|.. :.|||||..||||||||||||:..||.||||||
Fly 2972 LQGIRQATAMAAA-------VNAAANVSLGG-SDDDEGSNVATDGSTLRTSPAEPAGSGGSESGG 3028
Human 2989 SAVDSVAGEHSVSGRSSAYGDATAEGHP-----------AGPGSVSSSTG--AISTTTGHQEGDG 3040
|.|:|:.| .|.|||.:||......| .||..|:.|.| .:|..:..::.:.
Fly 3029 SGVESIGG---TSARSSNFGDHANASPPRQGSTKDDQEQPGPSGVAGSGGVAVLSAMSSSEDNEA 3090
Human 3041 SEGEGEGETEGDVHTSNRLHMVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEK 3105
:|.: ..::||.:|:.:||.::|.|.......|::|||.:||||||||||:|.:|:
Fly 3091 NEDD----------KLSKLHDLRIAVLESIIQHLGTFDLCNGLQAIPLIQVILMLTTDLNGNNER 3145
Human 3106 DKGALDNLLSQLIAELGMDKKDVSKKNE-RSALNEVHLVVMRLLSVFMSRTKS---GSKS---SI 3163
|:..|.:||:.|:..:.:.|:..:.:.| :...|||.|.::.|..|.|.:||| |:.| ..
Fly 3146 DQQVLHDLLTALVDYVEIGKRGAAARMETKCPGNEVRLALLSLFGVLMGKTKSKQTGTTSPPHQF 3210
Human 3164 CESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATS----------------- 3211
.::||.::|.||..|..|||..|.|..|.:||.:||:...| |.|..
Fly 3211 KDNSSFVASTTANVLSKSGAFVYALEALNTLLVHWKNVLGD--PYAAGGGLASQSAQASGGASGP 3273
Human 3212 --QLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKITDTNSRIPPPV 3274
|||||......||:|......|:|.: .|:||:|..||||:::||||||.:::..:.......
Fly 3274 GVQLLKPIKHGPKPDISILIPHNYLKNY-PDIFESYDGLLTEIIVRLPYQILRLSSAHPDNYDSG 3337
Human 3275 FDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIF 3339
|..:..:.|.||:|:.....:||||||||::|||||||:|..||.|:||:|.|.:|::
Fly 3338 FCEAMTFTLCEYMMLNLNTLLRRQVRKLLMYICGSKEKFRMYRDGHSLDAHFRVVKRV------- 3395
Human 3340 LRASVVTASSGS-------ALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVS 3397
.::|::.:|: .|.||.|:.|.|||:.|.||:..||.||||||:..:..|..|::::
Fly 3396 --CNIVSSKTGAPYNANPPMLSYDALVELTEHLRTCQEISQMRTGNWQKFCVVHEDALAMLMEIA 3458
Human 3398 -FLVDEGVSPVLLQLLSCALCGSKVLAALAASSGSSSASSSSAPVAASSGQATTQSKSSTKKSK- 3460
:.:|:||||:::|||..|:| :.|..:.|.||..|..:|:...|
Fly 3459 CYQLDDGVSPIIIQLLQAAVC--------------------NLPPPSGSKQAQPQPSTSSASGKL 3503
Human 3461 KEEKEKEKDGETSGSQEDQL-CTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHI 3524
:.::||.:|.:...|:.|.. |...|:|:.::|....:|:|:|.||||:|.:.:|||||.....:
Fly 3504 RTDREKSEDTDAYYSKFDPAQCGTFVHQIFRYACDALIIRFVRIFLLENNITQLRWQAHSFMTGL 3568
Human 3525 YRNSSKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQ 3589
:.::::.|:|.||::.|::||.:|.|||:.|||||||||.:|.|....::|.|:..:||::||.|
Fly 3569 FEHANERQREKLLNIFWNLWPLVPTYGRRTAQFVDLLGYLTLSTRSITERLPEFVSRAVDVLRQQ 3633
Human 3590 NHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKL 3654
|.:|..|||:.||.||..:::.:||||||:|||||||||||...|||.|:|.|::||||..:.||
Fly 3634 NELLCKHPNAPIYTTLESILQVNGYYLESEPCLVCNNPEVPMANIKLPSVKSDSKYTTTTMIYKL 3698
Human 3655 IGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKID 3719
:..|||||:.|:|.||||||||||||:|||||:|||:|||||:||.||||:.|.|...|||:|||
Fly 3699 VQCHTISKLIVRIADLKRTKMVRTINVYYNNRSVQAVVELKNRPALWHKARSVSLQSAQTELKID 3763
Human 3720 LPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEK 3784
.||||.|.|||||||||:|....|:|.||||||||:|||.|||||||||||:||||||:||||||
Fly 3764 FPLPITACNLMIEFADFFETVSGSSENLQCPRCSAAVPAYPGVCGNCGENVFQCHKCRAINYDEK 3828
Human 3785 DPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQL 3849
|||||::|||||||:|||.:||:.||||||||:.|||.|.||.|::.|::|||.|.||:.::..|
Fly 3829 DPFLCHSCGFCKYAKFDFSMYARVCCAVDPIESAEDRVKTVSLIHSSLERADRNYRQLLTNKQML 3893
Human 3850 ENLLCKVNE-AAPEKPQDDSGTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFAS 3913
|.|:.||.| .:.::..:|: ...:.||| .||:.|..|||:||.:.:.||:|||||:|||.|.
Fly 3894 ELLIQKVAEHRSSDRMVEDN--MASVHSTS-QVNKIIQLLAQKYCVESRTSFEELSKIVQKVKAC 3955
Human 3914 RKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRA 3978
|.||:.||.||:: ||..... |..|..:.::.:|||||.|.||.|:|||||
Fly 3956 RSELVAYDRQQQD----------QPPVNPG-----STTGAENPTTNRCYGCALASTEQCLTLLRA 4005
Human 3979 LATNPALRHILVSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTA 4043
:|.|...|..|.||||:.||.::|||||...::||||.|:.:||:||.||...:..|:..:|..|
Fly 4006 MAYNYDCRVCLYSQGLVSELAEHNLRRGTPLIQEEVRNLLVVLTKDNAEACMHLLQLVTTRVKNA 4070
Human 4044 LKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNI-KTPVVVENITLMCLR 4107
|.|......|.:::..||.||...:.::|.|||.:|:....||:....: :.||.. :...|||
Fly 4071 LMGSIPLISLEAAVHQEMTLLEVLLGQDDICWEYKLKVIFELFISNCRLPRGPVTA--VLHPCLR 4133
Human 4108 ILQKLIKPPAPTSKKNKDVPVEALTTVKPY-CNEIHAQAQLWLKRDPKASYDAWKKCLPIR---- 4167
|:|.||.|..|.||.|:.|....|.::|.: .|.:..:| ||..|....|.||.|.:|..
Fly 4134 IMQNLICPVLPGSKPNQKVATTDLCSMKMFEGNTVDYRA--WLNSDRNHEYAAWSKRMPSNNQAK 4196
Human 4168 ---------GIDGNGKAPSKS--ELRHLYLTEKYVWRWKQFLSRRGKRTSPLDLKLGHNNWLRQV 4221
...|...||.|| |:|..:|:|||..||::.:..:.:...|| :.:..|::.:
Fly 4197 LKNAKDQNVAASGGSDAPPKSRREVRVAFLSEKYGKRWRERVLDKQRVIKPL---VFNAKWIQPL 4258
Human 4222 LFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLITSAHWK 4286
||...::..||.||:::.:|:....|:||.|::|||:|..:..|||.:||||.||:.:.|...|.
Fly 4259 LFNANSRFGRQLACSLLSSLSRTNERRQQALNMLTSFLKHVGEAGEASAEYLMLYKNMATEQPWL 4323
Human 4287 VYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRL 4351
.||..:|||..:..|:..||:::..:||.:||:||..||||:....||...:|..:|:|.:|:|:
Fly 4324 QYLVLKGVLSQISQLLAIEISKVHRMEEYSLSSDLSLGYALRQYVELLWLLLECPNIRRTYKTRM 4388
Human 4352 VGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRT 4416
:|.||..||.||.||||||:|||:.|:.|||||||||:|||.||:|||.:.|:|.::..::|.:|
Fly 4389 LGPVLESYLALRSLVVQRTRLIDDAQEKLLEMLEDMTSGTEEETRAFMEILIDTVEKTRMNDIKT 4453
Human 4417 PVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQ 4481
|||:||||.|||:|||::.:||::||||||||||||||||.||||.|:|.|:||||||:|||||.
Fly 4454 PVFVFERLYSIIHPEEHDESEFYMTLEKDPQQEDFLQGRMLGNPYPSSEMGLGPLMRDVKNKICT 4518
Human 4482 DCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEG---EPMRIVYRMRGLLGDATEE 4543
||:|:||||||:|||||||||||||||||.:||||||.. || :.|||||||||||||||||
Fly 4519 DCELIALLEDDNGMELLVNNKIISLDLPVKDVYKKVWLA--EGGDRDAMRIVYRMRGLLGDATEE 4581
Human 4544 FIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIRDFKQGRHLLTVLLKLFSYCVKVK 4608
|:|:|::.:.|:.|.|::|:||.|:|.|.||..||.|:..::...:.|.|:.||||||..||||:
Fly 4582 FVETLNNKSQEQVDTEQLYRMANVLADCNGLRVMLERIGSLQRISRNRELIQVLLKLFLICVKVR 4646
Human 4609 VNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGN 4673
..::.|.:.|:..:|.:|..|.:.|.:|.:|..| ||.||:|.|||.||.::.::.|......
Fly 4647 RCQEVLCQPEIGAINTLLKVLQMCLQSENDSIQS---AVTEQLLEIMETILSKAASDTLDSFLQF 4708
Human 4674 LLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCNFDKYDE 4738
.|..|..:.:..|:...:...||:|||||:.|:|::..|.:|...||.:|.|.||...||:::|.
Fly 4709 SLTFGGPEYVSALISCTDCPNVRNNPSVLRHLIRVLAALVYGNEVKMALLCEHFKDTLNFNRFDN 4773
Human 4739 DHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAK----NLDADIW 4799
:.:.:::..|:.||.:...|::|..|..|||.|:..||.:.:|.|:.:|.|..| ..|:|..
Fly 4774 ERTPEEEFKLELFCVLTNQIEHNCIGGTLKDYIVSLGIVERSLAYITEHAPCVKPTLLRTDSDEL 4838
Human 4800 KKFLSRPALPFILRLLRGLAIQHPGTQVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHP 4864
|:|:|||:|.:|||.|.||:..|..|||.|..|.||.:|:||||||||.:|:|||||||||....
Fly 4839 KEFISRPSLKYILRFLTGLSNHHEATQVAISKDIIPIIHRLEQVSSDEHVGSLAENLLEALSTDS 4903
Human 4865 DVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCI 4929
....::...|..|||||||:|||.|:|.|..|||.|||||||..|.::|:::|:|.:|.||||.|
Fly 4904 ATAARVQQVRDFTRAEKKRLAMATREKQLDALGMRTNEKGQVTAKGSILQKIEKLRDETGLTCFI 4968
Human 4930 CREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWE 4994
|||||..||.|||||||||||..:||.|.|.||..||:||:|||:||.|||.:|:||.|||:|||
Fly 4969 CREGYACQPDKVLGIYTFTKRCNVEEFELKSRKTIGYTTVTHFNVVHVDCHTSAIRLTRGRDEWE 5033
Human 4995 SAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAM 5059
.|:||||||:||||||:|||.|.|:||:.|:.||::|:||.|.:.:.:|..::||:|||.:|||.
Fly 5034 RASLQNANTRCNGLLPLWGPAVGEAAFSACMTRHSSYMQESTQRCDISYTSSVHDLKLLLVRFAW 5098
Human 5060 EQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLE-QPKEKWVESAFEVDG 5123
|:||..|.||||.:||:|.:||::...:|:|.::|:.:|:.|.|..:|: .|.|||:|..:||||
Fly 5099 ERSFHDDAGGGGPQSNMHFVPYLLFYSVYLLLSSRSAARDSKTLLTYLQAPPSEKWLECGYEVDG 5163
Human 5124 PYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRL----TDKAVKDYSAYRSSLL 5184
|.:...::|.:...|.|...::..|:|::..:|.|.|:|....:. .|:.||||:.|:..|:
Fly 5164 PLFMATISLSLHSRELWNKHKLAHLKRMIAVAQGRHVSPAVLCKALLAPADRQVKDYTVYKPFLM 5228
Human 5185 FWALVDLIY-NMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFL 5248
.|||||||| |:||.|.|...| .|..||.:|:|.||..:.::.|..|:|..|||:|..:|.||.
Fly 5229 MWALVDLIYDNLFKTVSTPKEE-DWPISLFDYLRKNDEALLKSTDSILQTLTEEFLPCTSFVEFC 5292
Human 5249 DVAGLLSEITDPESFLKDLLNSVP 5272
||||||..|..|::|::::|.::|
Fly 5293 DVAGLLHLIEHPDNFIEEILAALP 5316
| 
