Protein Alignment TUT4 and MTPAP

DIOPT Version :10

• Sequence 1: XP_005270733.1
• Gene: TUT4 / 23318
• HGNCID: 28981
• Length: 1652
• Species: Homo sapiens
• Sequence 2: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 77/275 - (28%)
• Similarity: 130/275 - (47%)
• Gaps: 35/275 - (12%)

Human   996 FGSSKNGFGFRDSDLDICMTLEGHENAE-----------KLNCKEIIENLAKILKRH-------- 1041
            ||||.||||....|||:.:..:....|:           ..:.||.:.|.....:||
  Fly   217 FGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDML 281

Human  1042 ----PGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTM 1102
                ||:.::..|..|:|||:|:.|....||.|:|:.|....:.:.:|..:..:||||:.|.:|:
  Fly   282 HLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTI 346

Human  1103 KVFAKRCDIGDASRGS-LSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMV--DGWNAFF 1164
            :.:|:.|.:.:.|.|. :|:::...:|::||||.:.|::|.:..:....:.....|  ||.|..|
  Fly   347 RRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTF 411

Human  1165 FDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAI 1229
            ....:.|..|    .:|..||.||.|....||: :|||....||:.:.|.|:..:    ...:.|
  Fly   412 TRNVDRLGFR----SRNQSSLSELLLQFFEFYS-QFDFHNRAISLNEGKPLSKPD----HSAMYI 467

Human  1230 EDPFDLNHNLGAGVS 1244
            .:|.:...|:...||
  Fly   468 VNPLEQLLNVSKNVS 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUT4	XP_005270733.1	rplD	97..>199	CDD:184900
		TUTase	254..471	CDD:465974
		PAP_assoc	628..677	CDD:427532
		TRF4	929..>1261	CDD:227585	77/275 (28%)
		NT_PAP_TUTase	971..1089	CDD:143392	32/115 (28%)
		PTZ00368	<1280..1375	CDD:173561
		Atrophin-1	1404..>1593	CDD:460830
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	32/115 (28%)
		PAP_assoc	427..>461	CDD:427532	14/34 (41%)