|
Human 112 LDDRLQPPSFDPSGQPRRDLHTSWKRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTET 176
|||..:....|.......: :.|.:.|.:.:....|:| |.||.| .|
Fly 275 LDDEEEDEEEDEDEDDEEE-NASMQSNADDMELDAQQE-------TRTEPS------------AT 319
Human 177 LLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRK-------YDEEAAS 234
..|:::.:..:.|:|.: ..|||...:...|:...:..: ..|| .::..||
Fly 320 TQQQHQQQDTEDLEENK-----DAGEASLNVSNNHNTTDSNNS----CSRKNNNGGNESEQHVAS 375
Human 235 KA--DEVGLIMTNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGP 297
.| |:.....||....|..:..|.....:.....:|..:|.:....:....:|...
Fly 376 SAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPA-------- 432
Human 298 RLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDY 362
..||:||:||..||.::|.|::. |:....||..||..|..|.:.|.:||.:|..| ..
Fly 433 ---VLLAAKDKEIKALLDELQRLRAQ----EQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQ-QI 489
Human 363 EEIKTELSILKA----------------MKL---------ASSTCSLPQGMA------------- 389
.|...|.:.|.| .|| |||...||:...
Fly 490 NEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPESTKAPVPAEDDEEDED 554
Human 390 ------------KPEDS------------------------LLIAKEAFFPT------------- 405
||||| |.|.||...|.
Fly 555 QAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAA 619
Human 406 -----------------QKFLLEKPSLLASPEEDPSEDDSIKDSLGTEQSYPSPQQ--------- 444
|..|:|:...||:........|::.:....:|.....||
Fly 620 AAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDALSEDAHHQQQQHHQQQHQHQQQHHQ 684
Human 445 -----------LPPPPGPEDPLSPSP----------GQPLLGPS----LGPDGTRTFSLSPFP-- 482
|...|......:|:. |..||.|| |....|.:.|.|..|
Fly 685 QQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTA 749
Human 483 ------------------------SLAS---GERLMM-------PPAAFKGEAGGLLVFPPAFYG 513
|||| |.:.:| ...|....|.......|.|..
Fly 750 AGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLP 814
Human 514 AKP--PTAPATPAPGPEPLGGPEPADG-----GGGGAAGPGAE---------------------- 549
..| ..|.|..|.|.:..|....||. .|...||...|
Fly 815 GLPAFQFAAAQVAAGGDGRGHYRFADSELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMD 879
Human 550 ---EEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIK 611
.:.|||..|:.:|:|.|..||||||:|..|:||||||:|||:|::||||.|||.||::.:.|
Fly 880 KYANQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRK 944
Human 612 MKQFLSDEQNVLALRTIQVRQRGSITPRIRTPETG--------SDDAIKSILEQA---------- 658
|..:..|:..|:.|::: :.::.|..|:......| |:|.|..||.:|
Fly 945 MHAWACDDNAVMLLKSL-IPKKDSGLPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVA 1008
Human 659 --KKEIESQKGGE-----------PKTSVAP-------LSIANGTTPASTSEDAIKSILEQARRE 703
:::.....||| |::..:| |.......|...:....:...||..||
Fly 1009 QHREQERRSHGGEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQRERE 1073
Human 704 MQAQ-------QQALLEMEV---APRGRSVPP---SPP---ERPSLATASQNGAPALV------- 745
.|.: :.|.|..|: .||..:.|. ||. ....:..|:.|..||:.
Fly 1074 QQQRLRHDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHV 1138
Human 746 ----------KQEEGSGGPAQAPLPVLSP-AAFVQSIIRKVKS-EIGDAGYFDHHWASDRGLLSR 798
.|::.....|||..|..|. .|..|.::...:. .:..|...|......|..|..
Fly 1139 FEREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRSSLEH 1203
Human 799 PYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVPPEDEAAAGAEDEPPRTGELKAEGATAEAGA 863
...|.|.|........|....:||. ..|...|.||...:..|.....|.|......||::.:.|
Fly 1204 SAGSSSCSKDGERDDAYPSSLHGRK-SEGGGTPAPPAPPSGPGTGAGAPPTAAPPTGGASSNSAA 1267
Human 864 RLPYYPAYVP-----------------------------------------RTLKPTVPPLTPEQ 887
..|...:.:| |..|..:||:|.:|
Fly 1268 PSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQRPTKAVLPPITQQQ 1332
Human 888 YELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPF 952
:: |:..::|.::.|:|||.|::..|.||:|||.|||||||||||:|:|||||..|||||||||
Fly 1333 FD--MFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPF 1395
Human 953 IRMQLWLSDQ--LGQAVGQQ----------PGASQASPTEPRSSPSPPPSPTEP------EKSSQ 999
|||:::|.|: :.:.|..| .|:...||..|:...|...:.:.| |...|
Fly 1396 IRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQ 1460
Human 1000 EP--------------LSLSLESSK---------------------------------ENQQP-- 1015
|| :|.:::..: :.|.|
Fly 1461 EPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQ 1525
Human 1016 EGRSSSSLSGKMY----------------------SGSQAPGG---------------------- 1036
:...:::.:..:: :|...|||
Fly 1526 QHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPV 1590
Human 1037 ----------------IQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDL 1085
:.|:.|::.:|||:.||.::||.|..||:||::|||::|||:|||||:|
Fly 1591 HGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSEL 1655
Human 1086 LSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTG-------SD 1143
||:|||||.||:||||||:||||||:|.:|||:|:.:|...::|..:|| ||| ||
Fly 1656 LSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRR----STGPNQQDNSSD 1716
Human 1144 SESPATR---SECPSP--------CLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQT 1197
:.|..|. :..|.| ...|. ||.||:.:.|:|||||.|:.|:|||:..|
Fly 1717 TSSNDTNDFYTSSPGPGSVGSGVGGAPPS-------KKQRVLFSEEQKEALRLAFALDPYPNVGT 1774
Human 1198 IELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPD 1262
||.|:.:|.|.|.|:.|||||:|.|::::: |.| |.|..:|.|:
Fly 1775 IEFLANELGLATRTITNWFHNHRMRLKQQV------------PHG-----PAGQDNPIPS----- 1817
Human 1263 SETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRI-KQEQMEEDAEEEAGSQPQDSGELDKGQG 1326
..||..|..|..|.|| .|:::.|..:|..|. .|
Fly 1818 --------------------RESTSATPFDPVQFRILLQQRLLELHKERMGM-----------SG 1851
Human 1327 PPKEEHPDPP--------GND--GLP------KVAPGPLLPGGSTPD------------------ 1357
.| .|.|| |.. |:| ..|......|.|..|
Fly 1852 AP---IPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDL 1913
Human 1358 -CPSLHPQQ--------ESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSPGLMMSVSPV 1413
.|:|..:: |.|.|.....|..|.:......:.:....:...||.::....||.:..
Fly 1914 SMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVR 1978
Human 1414 PSSSAPISP---SPPGA--PPAKVPSASPTADMAGA 1444
.|...|.:| :|.|| .|:.|.:|...|..|.|
Fly 1979 SSRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAA 2014
| 
