DRSC/TRiP Functional Genomics Resources

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Protein Alignment FMOD and CG18095

DIOPT Version :9

Sequence 1:NP_002014.2 Gene:FMOD / 2331 HGNCID:3774 Length:376 Species:Homo sapiens
Sequence 2:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster


Alignment Length:291 Identity:75/291 - (25%)
Similarity:139/291 - (47%) Gaps:46/291 - (15%)


- Green bases have known domain annotations that are detailed below.


Human   105 SRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTR 169
            ::::|:...:|.::|::....:....|..:.|..|.::  |:..|.|.:...|::|.|.:|.:::
  Fly    87 TKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLS--KLSVKSFEQYPQLQQLDLRYNRISQ 149

Human   170 MPGPL---PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ--EVGS------------ 217
            :....   ...|:.|:|:.||::.:..:...||..|::|.||||.|:  |:.|            
  Fly   150 IENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRL 214

Human   218 -----------SMRGLRSLILLDLSYNHLRKVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAP 268
                       |.|||..|:.|:||.|.|:|:...:.|   .|:.|.:.:||:..:......|..
  Fly   215 DQNLLSSLQFLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLD 279

Human   269 KLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP----VNTNLENLYLQGNRINEF 328
            .|..:.:|||.:  :.:...:.:| .:||:||:|:|.|..:|.    .||.||.:.|..|:|.|.
  Fly   280 SLERLNISHNYV--DKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEI 342

Human   329 SISSFCTVVDVVNFSKLQVLRLDGNEIKRSA 359
            |...      :.|.:.|:.::|.||.|..:|
  Fly   343 SSQM------MFNQNHLRYIKLSGNAISDAA 367

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
FMODNP_002014.2 PRK15370 <81..>309 CDD:185268 58/235 (25%)
LRR 1 106..127 3/20 (15%)
leucine-rich repeat 107..130 CDD:275380 3/22 (14%)
LRR 2 130..151 5/20 (25%)
leucine-rich repeat 131..156 CDD:275380 6/24 (25%)
LRR 3 156..176 4/22 (18%)
leucine-rich repeat 157..177 CDD:275380 4/22 (18%)
LRR 4 177..198 5/20 (25%)
leucine-rich repeat 178..201 CDD:275380 7/22 (32%)
LRR 5 201..222 11/45 (24%)
leucine-rich repeat 202..224 CDD:275380 13/46 (28%)
LRR 6 224..245 8/23 (35%)
leucine-rich repeat 225..245 CDD:275380 8/22 (36%)
leucine-rich repeat 246..269 CDD:275380 5/22 (23%)
LRR 7 246..266 4/19 (21%)
LRR 8 269..289 4/19 (21%)
leucine-rich repeat 270..314 CDD:275380 14/48 (29%)
LRR 9 294..315 10/24 (42%)
leucine-rich repeat 315..334 CDD:275380 7/18 (39%)
LRR 10 316..335 6/18 (33%)
LRR 11 344..365 6/16 (38%)
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566 6/35 (17%)