Protein Alignment ICOSLG and zgc:172120

DIOPT Version :9

• Sequence 1: XP_024307828.1
• Gene: ICOSLG / 23308
• HGNCID: 17087
• Length: 473
• Species: Homo sapiens
• Sequence 2: NP_001121748.1
• Gene: zgc:172120 / 799440
• ZFINID: ZDB-GENE-080204-46
• Length: 273
• Species: Danio rerio
• Alignment Length: 270
• Identity: 67/270 - (24%)
• Similarity: 122/270 - (45%)
• Gaps: 33/270 - (12%)

Human    11 LLFSSLRADTQEKEVRAMVGSDVELSCA-CPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLE 74
            :|.:....:..:|.:.|:.|....|.|. .|:   .:|:::.|.||..|...||.....|...||
Zfish    11 VLVAPFEVNAPDKHLLALRGHSAVLGCEFTPD---LNLSNLVVTWQREEDSQVVHSFYYQQDQLE 72

Human    75 NVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFS 139
            .....|.:|..:....:.:|:.|:|:..|:.:|..::.|:| |.:.|.... |:|||  ..|.:|
Zfish    73 RQSPEYHSRTSLFVTELHKGNASIRIAAVSWKDAGRYLCIV-SNTKGTGRA-SMEVT--YGALYS 133

Human   140 VPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSL---LDQALQNDTVFLNMRGLYDVVS 201
            .|.:|...:.|...:.|   ...|:|:|.|.|:::.|.:|   |:.....:.      |||.:.|
Zfish   134 EPRLSIHLNSSALTVEF---ETEGFPKPEVIWVDEHDQTLSCPLELLKHTED------GLYLIKS 189

Human   202 VLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLL 266
            ...: :...||:...::|.||.||:........|    :.|..||      ..||..:|:::|::
Zfish   190 RYEV-KKQVVNVTFTLKNHLLNQNIHRPVTFSYD----ENIKSNP------GTATVVVLSLVCIV 243

Human   267 VVVAVAIGWV 276
            :::.|.  |:
Zfish   244 LLIGVI--WL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ICOSLG	XP_024307828.1	V-set	20..131	CDD:311561	29/111 (26%)
		Ig	153..>212	CDD:325142	13/61 (21%)
zgc:172120	NP_001121748.1	IG_like	23..127	CDD:214653	29/108 (27%)
		Ig	30..126	CDD:299845	26/100 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1537230at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920