Protein Alignment ICOSLG and zgc:112965

DIOPT Version :9

• Sequence 1: XP_024307828.1
• Gene: ICOSLG / 23308
• HGNCID: 17087
• Length: 473
• Species: Homo sapiens
• Sequence 2: NP_001018542.1
• Gene: zgc:112965 / 553735
• ZFINID: ZDB-GENE-050522-10
• Length: 325
• Species: Danio rerio
• Alignment Length: 216
• Identity: 54/216 - (25%)
• Similarity: 90/216 - (41%)
• Gaps: 49/216 - (22%)

Human     1 MRLGSPGLLFLLFSSLRAD-----TQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK 60
            :::..|.::.:....:.||     .....:.|.:|:.|.|.|...|.  ..:.|:.|.|:.::|:
Zfish    10 LKMHQPKIVLMTVMLMIADGLVVRGPSAPLSAPLGASVVLPCYVDEA--LPVEDLEVEWRRADSE 72

Human    61 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEV 125
            |:|..:....|..|.....|.:||......:..|:|||||.|:|.|||.::.|.|.||....:.|
Zfish    73 TLVHLYQDGESRAEVQQQDYHDRAHFFTEEIQHGNFSLRLDNLTAQDEGEYRCRVHSQQDSEETV 137

Human   126 LSVE-------------VTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRP----NVYWIN 173
            :.::             |::||.                :::|..| |::.:..|    .|.| .
Zfish   138 IKIKDVERLLVSGTNRSVSIHVG----------------EDVTLNC-SVDSHITPEHIEEVLW-R 184

Human   174 KTDNS-----LLDQALQNDTV 189
            |||..     ||.|  .|.||
Zfish   185 KTDKDGDILILLYQ--NNKTV 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ICOSLG	XP_024307828.1	V-set	20..131	CDD:311561	33/123 (27%)
		Ig	153..>212	CDD:325142	15/46 (33%)
zgc:112965	NP_001018542.1	IG_like	36..141	CDD:214653	33/106 (31%)
		Ig	44..141	CDD:299845	32/98 (33%)
		V-set	151..250	CDD:284989	18/73 (25%)
		IG_like	153..257	CDD:214653	18/71 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910