Protein Alignment FKBP15 and CG30075

DIOPT Version :10

• Sequence 1: NP_056073.1
• Gene: FKBP15 / 23307
• HGNCID: 23397
• Length: 1219
• Species: Homo sapiens
• Sequence 2: NP_725390.1
• Gene: CG30075 / 246437
• FlyBaseID: FBgn0050075
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 175
• Identity: 33/175 - (18%)
• Similarity: 69/175 - (39%)
• Gaps: 50/175 - (28%)

Human   570 IIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSN--LMMEKRNNSLQTATENTQARVL 632
            ::.||:.      ::|...:||:| |..||.|....:.|:.  .|...|.:..|.|.|....|:.
  Fly    22 LLNENDN------DQSLSSDEQDD-IFFLIYRKAHTLFQAGKLWMRRMRYHDAQRAFEKAITRLK 79

Human   633 HA-----EQEKAK--------------------------VTEELAAATAQVSHLQLKMTAHQKKE 666
            ..     ||:..|                          |.:||...|.. :...|.:..|.:..
  Fly    80 TCKTSSFEQQCRKKDMLIALFESLMICFNKMRQSRCVCYVMKELRLLTIN-NPSALALCQHGRAL 143

Human   667 TEL------QMQLTESLKETDL---LRGQLTKVQAKLSELQETSE 702
            ::|      ::...::||:...   ::.::|::..:::||::|::
  Fly   144 SDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISKRITELEDTNQ 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FKBP15	NP_056073.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..66
		PH-like	70..168	CDD:473070
		Important for function in growth cone organization. /evidence=ECO:0000250	72..169
		FKBP_C	193..286	CDD:459735
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..349
		Atrophin-1	307..>495	CDD:460830
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..433
		FAM184	514..710	CDD:464788	33/175 (19%)
		Smc	<620..>882	CDD:440809	20/123 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	739..761
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..1219
		PHA03247	<951..1164	CDD:223021
CG30075	NP_725390.1	None