DRSC/TRiP Functional Genomics Resources

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Protein Alignment FKBP15 and fkb-3

DIOPT Version :9

Sequence 1:NP_056073.1 Gene:FKBP15 / 23307 HGNCID:23397 Length:1219 Species:Homo sapiens
Sequence 2:NP_001379619.1 Gene:fkb-3 / 179113 WormBaseID:WBGene00001428 Length:261 Species:Caenorhabditis elegans


Alignment Length:99 Identity:32/99 - (32%)
Similarity:53/99 - (53%) Gaps:13/99 - (13%)


- Green bases have known domain annotations that are detailed below.


Human   195 EVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVP 259
            :.||:|...||    .|...|...||:.::::....|:|||:||||.:..|.||.:|.||.:::|
 Worm   164 QAGDTLHQQYT----LNLEDGSFIDSSWSRNRPFIFKMGSGQVIKGMDIAMEGMCQGEKRKVVIP 224

Human   260 PACAVGSEG----VIGWTQATDSILVFEVEVRRV 289
            |..|.|..|    :.|     :|.|.|::.:.::
 Worm   225 PELAYGENGRPPAIPG-----NSYLHFDLSLEKL 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FKBP15NP_056073.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 41..66
PH-like 70..168 CDD:302622
Important for function in growth cone organization. /evidence=ECO:0000250 72..169
FKBP_C 193..286 CDD:278674 32/94 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..349
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..433
COG1340 511..781 CDD:224259
TIMELESS_C 589..>777 CDD:252956
SPEC 686..908 CDD:295325
DUF4515 694..871 CDD:291649
Ax_dynein_light <715..780 CDD:287215
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 739..761
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 931..1219
Extradiol_Dioxygenase_3B_like <1014..>1072 CDD:294399
fkb-3NP_001379619.1 FkpA 55..250 CDD:223619 32/94 (34%)
FKBP_C 159..250 CDD:395196 32/94 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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