Protein Alignment ACSL6 and Acsx3

DIOPT Version :10

• Sequence 1: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_650831.1
• Gene: Acsx3 / 42354
• FlyBaseID: FBgn0038733
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 135/606 - (22%)
• Similarity: 224/606 - (36%)
• Gaps: 145/606 - (23%)

Human   100 IGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQE--VADRAEFLGS-- 160
            |.||.| |.:|:|...::.::....:           |:..|....:|..|  :..|||...:
  Fly    15 IWSGDQ-LEYYFDPHLSIGEIIFNEM-----------RRHPQLIAQISATENTILTRAELQANAM 67

Human   161 ---------GLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIIN 216
                     ||||.:       .:|:.|:|......|..||:...:....|..:.....|..:.:
  Fly    68 HIASYMRSLGLLQMD-------IVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLFS 125

Human   217 TADISTVIVD-----KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAV 276
            ....:.:..|     |.:.|...|:         :|:|.:          |....| .|:..|.:
  Fly   126 ITRPNIIFCDGDEFEKVRSATAQLD---------VKIITM----------RNHPSG-SIRIDQVL 170

Human   277 EDCGQENHQAPVPPQPDD--LSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCAD 339
            ....::|.|.....|.:|  |:|:| :|||||.||...:|:...:.:.|..|...:.|::.:..|
  Fly   171 STPIEKNFQPVRLEQGNDQTLAILC-SSGTTGIPKAVTITNSRQILNSSHSLTTNDVQYSHSTLD 234

Human   340 VHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFS 404
            .....|       ..|.|.|:          ...|:::|:       ||.  |....|:.::  .
  Fly   235 WITGLL-------TTVTSGVF----------STKRIIADN-------IFD--PEFFMRLVEE--H 271

Human   405 QANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLG 469
            |..     |::       ||.....::.|    ...|.....:||    |..:.|.:.||.....
  Fly   272 QIT-----WII-------QAPAHMAMMVN----SPSFTTSDLSSL----RYYLFGGSRASVETQH 316

Human   470 FLRAALG--CQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGE-- 530
            .:|:.|.  | ::..||.||..:........|.....||        :||...:|.....|||
  Fly   317 RIRSRLSKDC-LHFAYGFTELGSMAALNLHFDEKPNSVG--------RLVAGLKLKVICEKGESL 372

Human   531 -----GEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQG 590
                 ||:|:.....:.||..:|:.|.:..|...|.||||:|.....|.:.|::|||.:.|....
  Fly   373 GPDEVGELCLWNGQYWAGYYGNPEETHKMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNI 437

Human   591 EYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLC----T 651
            .|. |.:||::..:...|.::.|.|       |...:...|...:..:|||...|..|:.    |
  Fly   438 MYY-PNEIESVISKMPDVVEVCVFG-------VWNEINGDEATAAVVKKRGSALTAQDIVDYVET 494

Human   652 NKDLK-------KAILEDMVR 665
            :.|.|       ..|:||:||
  Fly   495 HIDAKYKQLNGGAIIVEDLVR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	127/565 (22%)
Acsx3	NP_650831.1	Firefly_Luc_like	47..522	CDD:341237	126/562 (22%)