Protein Alignment ACSL6 and Acsx2

DIOPT Version :10

• Sequence 1: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 136/611 - (22%)
• Similarity: 219/611 - (35%)
• Gaps: 194/611 - (31%)

Human    92 SGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQ-------WLSYQ 149
            ||.:|.|:           |::..|:.|:..|.|.          |:|::.:|       .|:..
  Fly    20 SGCSRHSL-----------YNEELTVGQIIFRQLQ----------RQPQRIFQISHTDNTRLTRF 63

Human   150 EVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRY- 213
            ::...|..:|..|.....|..|| .:|:.|:|                       :...||:.|
  Fly    64 QMLQNAAKIGCYLRDQGFKKETD-LVGLMARN-----------------------STHVGALAYG 104

Human   214 -IINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFE-EALKERGQKCGVVIKSMQ-- 274
             :.|......|..:.....:..|..:.|..      |:..|..: |.:|:.|...|.:|.::.
  Fly   105 CLFNGTPFHAVNPNLEHNTISSLYKITRPR------ILCCDTADYEKIKDIGASLGALIITVNGK 163

Human   275 -----AVEDCGQENHQAPVPPQPDD-------------LSIVCFTSGTTGNPKGAMLTHGNVVAD 321
                 :|.|..|.       |.|||             ::|:| :|||||.||...|::...:.:
  Fly   164 LPGVISVADILQN-------PLPDDYEPAQFQRGVDRTMAILC-SSGTTGTPKAVTLSNSRKLFE 220

Human   322 FSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPT 386
            ...:|...:.|:||:..|.....:.|       |.:.|:          |.:||:|.:|
  Fly   221 MHSYLGSDDVQYAPSTLDWLTGLITL-------VTAAVF----------GTVRLISSEM------ 262

Human   387 IFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGG 451
                            ||.|:         |....:|.||...|:.|..:          |.|..
  Fly   263 ----------------FSTAH---------FLDICEQHEVSWTIMANSHV----------AMLAN 292

Human   452 CVR-----------MIVTGAAPASPTV---------LGFLRAALGCQVYEGYGQTE--CTAGCTF 494
            |.:           ::..|......|:         .|.||.|        ||.||  ......:
  Fly   293 CPKTSAQKLRSLKHLLFAGGHCLVATLKKMQSFLHGSGILRNA--------YGLTEVGTLVSYNY 349

Human   495 TTPGDWTSGHVGAPLPCNHIKLVDVE-ELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSD 558
            .|....||  ||..:....:|:||.. :|.  ..||.|||.......:.||:.:|..|.|..||.
  Fly   350 DTQSKPTS--VGRLMANIRVKIVDSSGQLQ--GPKGLGEILCHNGQPWSGYVGNPLATAEMRDSA 410

Human   559 GWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYV-------HGD 616
            ||.||||:|.:.....|.|::|||.:.|.. |....|.::|.:..:...||::.|       .||
  Fly   411 GWYHTGDVGYFDEDHYLHIVERKKDMLKYL-GMMYYPHEVEEVIAQMPDVAEVCVFGIFRETEGD 474

Human   617 SLKAFLV---GIVVPDPEVMPSWAQK 639
            :..|.:|   |..: ||:.:..:.:|
  Fly   475 AAAASVVLRSGSKL-DPKHVEQYVRK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	125/562 (22%)
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	125/559 (22%)