Protein Alignment ACSL6 and Fatp3

DIOPT Version :10

• Sequence 1: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_726437.2
• Gene: Fatp3 / 37887
• FlyBaseID: FBgn0034999
• Length: 687
• Species: Drosophila melanogaster
• Alignment Length: 698
• Identity: 134/698 - (19%)
• Similarity: 212/698 - (30%)
• Gaps: 275/698 - (39%)

Human   105 QLLTHYYDDARTMYQVFRRGLSISGNGPCLGF---RKPKQPYQWLSYQEVADRAEFLGSGL---- 162
            |.:..|:.|         |||.   .|.|:..   .:.:.|..||...::......:.|.|
  Fly   149 QKIAGYFSD---------RGLE---RGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGES 201

Human   163 LQHNCKACT-------DQFIGVFAQNRPEWIIVELACYTYS---MVVVPLYDTLGPGAIRYIINT 217
            |.|:.|...       .:.:.|....|.:..:.|:..|.|:   :..|..:|.| |||:
  Fly   202 LLHSIKVANAKALIVGSELLDVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLL-PGAV------ 259

Human   218 ADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQE 282
             |:.|.:  |.||         :.|.|
  Fly   260 -DLVTAL--KTQK---------KLELP-------------------------------------- 274

Human   283 NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSG---FLKVTESQWAPTCADVHISY 344
              .|..|.:.....:..:||||||.||.|::|:...:...:|   .||::..       ||....
  Fly   275 --SAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSD-------DVVYDP 330

Human   345 LPLAHMFERMVQSVVYCHGGRVG----FFQGDIRLLSDDMKAL-----CPTIFPVVPRLLNRMYD 400
            |||.|           ..||.||    ...|...:|.....|.     |.            .::
  Fly   331 LPLYH-----------TAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCD------------RHN 372

Human   401 KIFSQANTPLKRWLL--EFAAKRKQAEVR----SGIIRNDSIWDEL-------FFNKIQASLGGC 452
            ...:|....|.|:||  .::..:::..:|    :|:  ...||.:.       ...:|..:..|.
  Fly   373 CTVAQYIGELCRYLLATSYSPDQQKHNLRLMYGNGL--RPQIWSQFVRRFGIPHIGEIYGATEGN 435

Human   453 VRMI-VTGAAPASPTVLGFLRA---------ALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGA 507
            ..:| :|....|    :||:..         .|.|..|.|....:....|....||.  :|.:
  Fly   436 SNLINITNRVGA----IGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQ--AGLL-- 492

Human   508 PLPCNHIKLVD----VEELNYWACKG-------------------EGEICVRGPNVFKGYLKDPD 549
                  :..||    |...:.:|.||                   .|::.||.   ..||....|
  Fly   493 ------VGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRD---ILGYFYFKD 548

Human   550 RTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVH 614
            |            |||..:|                   :||.||.:::|.|......:....|:
  Fly   549 R------------TGDTFRW-------------------RGENVATQEVEAIITNCVGLEDCVVY 582

Human   615 GDSL-----KAFLVGIVVPDPEVMPSWAQ--KRGIEGTYADLCTNKDLKKAILEDMVRLGKESGL 672
            |..:     ||.:..||.|:.:|...:..  .||....||     :.|...:|:::.|
  Fly   583 GVQIPHVEGKAGMAAIVDPERKVDMDYLSVVLRGSLPPYA-----RPLFIRLLDEIPR------- 635

Human   673 HSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
                                   |.|.|.|:.||       .:|.|.|
  Fly   636 -----------------------TATFKLKKREL-------AKEAYDI 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	124/656 (19%)
Fatp3	NP_726437.2	hsFATP4_like	136..653	CDD:341262	133/696 (19%)