Protein Alignment KIF13B and Kif13b

DIOPT Version :10

• Sequence 1: XP_011542759.1
• Gene: KIF13B / 23303
• HGNCID: 14405
• Length: 1847
• Species: Homo sapiens
• Sequence 2: NP_001398965.1
• Gene: Kif13b / 305967
• RGDID: 1303307
• Length: 1843
• Species: Rattus norvegicus
• Alignment Length: 1884
• Identity: 1613/1884 - (85%)
• Similarity: 1686/1884 - (89%)
• Gaps: 78/1884 - (4%)

Human     1 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65
            |||||||||||:|||||||.||||||||||:||||||||:||||||||||||||:||||||||||
  Rat     1 MGDSKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINTNLSKGDARGQPKIFAYDHCFWSM 65

Human    66 DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGL 130
            ||||:|||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 DESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGL 130

Human   131 FERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYK 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 FERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYK 195

Human   196 DIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERA 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 DIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERA 260

Human   261 TKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTA 325
            |||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||
  Rat   261 TKTGAAGDRLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTA 325

Human   326 MVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKS 390
            ||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
  Rat   326 MVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKS 390

Human   391 PELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNA 455
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||
  Rat   391 PELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQTSGIKVGDDKCFLVNLNA 455

Human   456 DPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSV 520
            |||||||||||||||||||||||||||||||||||||.||||..|||||||||||||||||||||
  Rat   456 DPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHGIIDIMPEGQVMLTPQKNTRTFVNGSSV 520

Human   521 SSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEV 585
            ||||||||||||||||||||||||||||||||||||:::.|:||::||||||.|||||||||||:
  Rat   521 SSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEEREASLKNDSSSEQLDADGDSSSEVSSEI 585

Human   586 NFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQN 650
            |||:||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||:||
  Rat   586 NFNFEYAQMEVTMKALGSNDPMQSILSSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPERQN 650

Human   651 CRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKV 715
            ||.:||.|||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
  Rat   651 CRGVDRLSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREASYIAEELDKRTEYKV 715

Human   716 TLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 780
            |||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||:||.
  Rat   716 TLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLENRLLDMRDLYQEWKECEEDSPVS 780

Human   781 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRLSGDVG 845
            ||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||.:|
  Rat   781 RSYFKRADPFYDEQENHSLIGVANVFLETLFYDVKLQYAVPIINQKGEVAGRLHVEVMRLSGAIG 845

Human   846 ERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTS 910
            |||||||:..|||.|||.|||:|||||||||||||||||.|||||||.||||||||.||||||||
  Rat   846 ERIAGGDDPTEVSSEKEVQENRLVCMVKILQATGLPQHLCHFVFCKYDFWDQQEPVTVAPEVDTS 910

Human   911 SSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKT 975
            ||..||||.||||||||:||||||||||||:||||||||||||||:|||||||||||||||||||
  Rat   911 SSPTSKEPQCMVVFDHCSEFSVNITEDFIEYLSEGALAIEVYGHKMNDPRKNPALWDLGIIQAKT 975

Human   976 RSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQE 1040
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat   976 RSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVIAAKDVPTGGIFQLRQGQSRRVQVEVKSVQE 1040

Human  1041 SGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEY 1105
            |||||||||||||||||||||||||:|:|||..||||||||||||||||||||||||||||||||
  Rat  1041 SGTLPLMEECILSVGIGCVKVRPLRSPKTHENIHEEEEDMDSYQDRDLERLRRKWLNALTKRQEY 1105

Human  1106 LDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHI 1170
            |||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||.||
  Rat  1106 LDQQLQKLVSKHDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMEAHI 1170

Human  1171 PVIFLDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCP 1235
            ||:|||||||||||||||||||| |||||||||||||||||||||.||||||||||||||||.||
  Rat  1171 PVVFLDLNADDFSSQDNLDDPEA-GWDATLTGEEEEEFFELQIVKHHDGEVKAEASWDSAVHNCP 1234

Human  1236 QLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGV 1300
            |||:|||.|||:|||:||.|||||||||||||||||||:|||||||||||||||:||||||||||
  Rat  1235 QLSKGTPADERVFLILRVAVQLSHPADMQLVLRKRICVHVHGRQGFAQSLLKKMTHRSSIPGCGV 1299

Human  1301 TFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAV 1365
            ||||||||||||||||||||||||||||||.|||||||.||||||||||||||||||||||||||
  Rat  1300 TFEIVSNIPEDAQGVEEREALARMAANVENAASADSEACIEKYLRSVLAVENLLTLDRLRQEVAV 1364

Human  1366 KEQLTGKGKLSRRSISSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQDLIPSYSLGSNKGRWE 1430
            ||||||||||:|||||||::||                     ||||||:|.||:||.|||||||
  Rat  1365 KEQLTGKGKLNRRSISSPSMNR---------------------LSGSRQELSPSHSLSSNKGRWE 1408

Human  1431 SQQDVSQTTVSRGIAPA-PALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRD 1494
            ||||||||.||||||.. ||||||||||.||||||:  .|||||||||.|||||||||||||
  Rat  1409 SQQDVSQTLVSRGIASGPPALSVSPQNNQSPDPGLN--PASYLNPVKSLVPQMPKLLKSLFP--- 1468

Human  1495 EKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQP-EMGPDVLVQT---MGAPALKICDKPAK 1555
            ::||:..|||..||||||:||....|.|.||.||||. ..||...:::   |.||.:||||||.:
  Rat  1469 DRRGRHSSPLVQQPVPRILVQPTFSDARATRTEEAQQGSPGPSGALESMVKMAAPTVKICDKPVR 1533

Human  1556 VPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLD----AAAPPGSM 1616
            |.|||   :...||...|.||||||||||||||||||||||||||:.|..|||    .:..|||.
  Rat  1534 VSSPP---STMVVTQPQEGQDGPPSPLSEASSGYFSHSVSTATLSETLTLGLDTTGLGSQTPGSP 1595

Human  1617 PT------APE-----------AEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPA-P 1663
            |.      .||           .:||.|...|..||.....|.|.|..|..|        .|| |
  Rat  1596 PALCQVTQEPELAFLSCTQSHPTDPEEPHIPPATPTQSTELEVPRPPLLSDP--------TPAVP 1652

Human  1664 GSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGN---APAPG-AGGQAL-----ASDSEEADEVP 1719
            .||||:|:||.|||.||:.||.   |.|.||:.:   :..|. |.||.|     .||||:|.|||
  Rat  1653 TSPFRIRKVRPSELTSFTGMLG---GASSGAQEDPVVSEDPSHARGQTLGRLEVTSDSEDASEVP 1714

Human  1720 EWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVR 1784
            |||||||:|.||.:|||:|||:||.|||||||:|||||||:||||||||||||||||||||||||
  Rat  1715 EWLREGEYVVVGTNKTGIVRYIGPTDFQEGTWIGVELDLPAGKNDGSIGGKQYFRCNPGYGLLVR 1779

Human  1785 PSRVRRATGPVRRRSTGLR-LGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS 1847
            |.|||||.|..||||:||: .||||||||||:||||||||||||||||.|||:|||||||||||
  Rat  1780 PGRVRRAAGTGRRRSSGLQPQGAPEARRSATISGSATNLASLTAALAKGDRSYKNPENRKSWAS 1843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF13B	XP_011542759.1	KISc_KIF1A_KIF1B	4..360	CDD:276816	346/355 (97%)
		Kinesin_assoc	357..469	CDD:465047	110/111 (99%)
		FHA_KIF13B	447..545	CDD:438782	94/97 (97%)
		COG4913	<611..>760	CDD:443941	141/148 (95%)
		KIF1B	756..802	CDD:463574	42/45 (93%)
		bMERB_dom	<1099..1143	CDD:463467	42/43 (98%)
		DUF3694	<1221..1278	CDD:463599	49/56 (88%)
		PHA03247	<1445..1704	CDD:223021	147/289 (51%)
		CAP_GLY	1725..1788	CDD:460154	52/62 (84%)
Kif13b	NP_001398965.1	KISc_KIF1A_KIF1B	4..360	CDD:276816	346/355 (97%)
		Kinesin_assoc	357..469	CDD:465047	110/111 (99%)
		FHA_KIF13B	447..545	CDD:438782	94/97 (97%)
		COG4913	<614..>760	CDD:443941	139/145 (96%)
		KIF1B	756..802	CDD:463574	42/45 (93%)
		C2-C2_1	<888..>952	CDD:463310	56/63 (89%)
		bMERB_dom	<1073..1143	CDD:463467	67/69 (97%)
		DUF3694	<1214..1277	CDD:463599	54/62 (87%)
		PHA03247	<1377..1715	CDD:223021	197/377 (52%)
		CAP_GLY	1720..1783	CDD:460154	52/62 (84%)