Protein Alignment WWC1 and SPAC167.07c

DIOPT Version :9

• Sequence 1: XP_011532787.1
• Gene: WWC1 / 23286
• HGNCID: 29435
• Length: 1185
• Species: Homo sapiens
• Sequence 2: NP_593378.1
• Gene: SPAC167.07c / 2542770
• PomBaseID: SPAC167.07c
• Length: 1029
• Species: Schizosaccharomyces pombe
• Alignment Length: 614
• Identity: 118/614 - (19%)
• Similarity: 203/614 - (33%)
• Gaps: 190/614 - (30%)

Human   487 LSSSMQSLSSGSSPGSLTSSRGSL------VASSLDSSTSASFTDLYYDPFEQLDSELQSKVEFL 545
            |:..:.|::|....|:.||:..||      ||..|.||..::    |||......:::..|....
pombe   171 LNCLVSSINSHRIEGTDTSAETSLLHCLAYVAPYLKSSELST----YYDSVMTFYAQIYPKQNMT 231

Human   546 LLEGATGFRPSGCITTIHE--DEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPC 608
            .||.....   ..:|.:..  ||.|.:..|   .....|.|           ...||:.:..||
pombe   232 NLEDIMSL---SLLTPVSSKTDENANSSSA---FLFHVLAS-----------DCFSSIENCIPP- 278

Human   609 SPLMADPLLAGDAFLNSLEFEDPELSATLCELSL-------GNSAQERYRLEEPGTEGKQ----- 661
                  .|:....|.:||:..:....::|..|.:       ||.      |....||.|.
pombe   279 ------DLIIDKVFSSSLQLSEEACISSLLNLGMIKVFSLAGNC------LHLLHTEYKNSSLWK 331

Human   662 ------------LGQAVNTAQGCGLKVACVSAAVSDESVAGDSGV----YEASVQRLG------- 703
                        .|::||:      ::..||....||.   |...    |.:.:|.:.
pombe   332 FCSYILDALYVFSGESVNS------RIQVVSDVDDDED---DENAFSQNYYSHLQMVAKHFSKNY 387

Human   704 ASEAAAFDSDESEAVGATRIQIALKYDEKN-----KQFAILIIQL--SNLSALLQQQDQKVNIRV 761
            |:::.......:|.:.:|.|..|.|....|     ..|...:|:|  ||.:::|        :.:
pombe   388 ANQSGIVQRSFAECISSTFITKAFKLVSSNTLQAMSHFYATMIKLFPSNRTSIL--------MYI 444

Human   762 AVLPCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGAQI 826
            :::..:|.:.    ||........:|:|    |..|...|:|....:|...|..:..:    .|:
pombe   445 SLVETNEGSL----TRSFSRFSWDMFSE----SPVYQLFHKKFDVQNVLKNDSGYWFQ----LQL 497

Human   827 SLAEVCRSGERSTRWYNLLSYKYLKKQSRELKPVGVMAP----ASGPASTVSWDQDAVSALLEQT 887
             |.:|     .|...:.::..::...:...|.|  |||.    .......:.||..|...:..::
pombe   498 -LIDV-----YSRMLFTMIDDEFHNDKQNPLYP--VMAEFCTVLKNLVLGLYWDVQAAKDVDCKS 554

Human   888 AVELEKRQEGRSSTQTLEDSWR-----------------YEETSENEAVAEEEEEEVEEEEGEED 935
            .|::.:.:.  |||..|:..:|                 |...:|.||.|.:|.|.....|.|.:
pombe   555 VVDISQLRV--SSTSLLQQLYRINSRKQFLPEDFFLMSEYFNLNEFEANALQESELASHAEAEIN 617

Human   936 VFTEKASPDMDGYPALKV-----------------------DKETNTETPAPSPTVVRPKDRRVG 977
            : |.|.....:..|.|.:                       ||:.|....
pombe   618 I-TYKFDNFSESRPRLNILNNCSFFLPFHFRIHLLQQLLLLDKQANGYAQ--------------- 666

Human   978 TPSQGPF--LRGSTIIRSKTFSPGPQSQY 1004
                 ||  |:.:.|.|::.|..|..:.|
pombe   667 -----PFGHLKHAVIRRNRIFDDGFDAFY 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WWC1	XP_011532787.1	WW	9..39	CDD:238122
		WW	55..84	CDD:278809
		ALDH-SF	429..>481	CDD:299846
		C2_Kibra	721..844	CDD:176062	26/129 (20%)
SPAC167.07c	NP_593378.1	HUL4	155..1029	CDD:227354	118/614 (19%)
		HECTc	676..1027	CDD:238033	5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900