Protein Alignment NUP160 and nup160

DIOPT Version :10

• Sequence 1: NP_056046.2
• Gene: NUP160 / 23279
• HGNCID: 18017
• Length: 1402
• Species: Homo sapiens
• Sequence 2: XP_031756356.1
• Gene: nup160 / 105947166
• -ID: -
• Length: 1439
• Species: Xenopus tropicalis
• Alignment Length: 1407
• Identity: 977/1407 - (69%)
• Similarity: 1169/1407 - (83%)
• Gaps: 18/1407 - (1%)

Human     1 MAAAGALERSFVELSGAERERP-RHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVT 64
            |||:..||||::||.|||||.. |:||:.::..  ..:.|.|..|||:.|||:.|.|||.|.|.|
 Frog    36 MAASVNLERSYMELIGAERETSRRNFRDLSLRP--DVSLVIGGPKYSDCAGGYCYNESGSLLSAT 98

Human    65 RNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHR 129
            |||||||.:..|||||:|.||||||||||:|||..|||:|||||::.||||.:|:|:||||||||
 Frog    99 RNRFIHWTSYADTLELVELSLDINLLNNAVRLKILNCSILPGGVHICETQNNIIVLILTNQTVHR 163

Human   130 LLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEAL 194
            |:|||||||||||::.||.:|||||||||.:|.||.|..:|||:||.:|||||||||||||||||
 Frog   164 LILPHPSRMYRSEIISDSHIQSIFTDIGKTNFHDPNNTYVIPAIPGRAPNSTASTAWLSSDGEAL 228

Human   195 FALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCV 259
            ||||..||||.|:|:||.|:.|:|::.|||||||||||||||||::||||..|:..|:|||||.:
 Frog   229 FALPSVSGGILVIKMPPRDMEGLVTIAELKQSSVMQRLLTGWMPSSIRGDPGPAHLPVSLAVHTL 293

Human   260 EHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMG-LYLG 323
            :||:::|||||||||||||||:|||||||||||||||.||:|.|||||||||||||.|:. ||||
 Frog   294 DHDSYLFALCQDHKLRMWSYKDQMCLMVADMLEYVPVSKDIRQTAGTGHKLRLAYSDTLEILYLG 358

Human   324 IYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLID--FALTSTDIWALWHDAENQTVVK 386
            :|:|.|::||||:||||.||||||||:|.||:||:||||||  |.|:|.:|||||.|.:||||:|
 Frog   359 VYLHTPRQGQFCVFQLVCTESNRYSLEHTSSIFTNQETLIDFTFTLSSMNIWALWLDDDNQTVMK 423

Human   387 YINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTER 451
            :||||.|.||.|||||:.|||::::.|.|:|:|:|.||:.||.||:||..||.||:||..:|:.|
 Frog   424 HINFERNQAGHWNPVFVNPLPDDDLAIGDEQEPQEAYLECLFAPGRFTIAALQKAIQILRKGSGR 488

Human   452 NLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHL 516
            .|||||.||||||||.||.|:|.:|.:|:.||||||.:..|.|||||.|||||||.||.||||.:
 Frog   489 VLDLSWEELKKEVTLTVEKEIQNAVVDYDVSQEEFRQINIENWCKFYTCCLQYQETLSRPLALVV 553

Human   517 NPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICLIKCLRLIEE 581
            :|:|||||||:||:||||.|.|.|:||||:|.|:|||.||:.|.||||.|.|::.||:||.:|.:
 Frog   554 HPNTNMVCLLRKGFLSFLAPCSSVEHLYLVPGEHLLTVDESVICDDVDGASDIVSLIQCLHMIAD 618

Human   582 SVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIRNPIHAIGLLIREMD 646
            .:|.||:..||.:|.:.||||:.|||||||:|..|::|:||:|.:|||:|||||.||..|::.||
 Frog   619 YITEDMAYQMESACCHPQSPERVAEQILEDLIANDIDNIMENIQNKLQDIRNPIQAISFLLQNMD 683

Human   647 YETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLG 711
            |||.::||:..:     |:|:||:.||||.||..:||:.::||::|||||||||||||.||:|||
 Frog   684 YETNMDMEQSQH-----NVRLNLSTLYGSVTASSVVCQAIYKISATRFLICRDLLILQHLLLRLG 743

Human   712 DAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGAL 776
            |..:.|.|||..:||:|:.|.|.||||||:|:|||:|||..||:|.|||||||||||||:|| .:
 Frog   744 DMALVGAGQLLHSQQELIPRAAQLLLSYYMIRWGSQCLACAVPVDLLESNLQHLSVLELSDS-QV 807

Human   777 MANRFVSSPQTIVELFFQEVARKH---IISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPS 838
            ...|:.|..||||||||::|.|||   :.:|||.|..:......|||.::|..||||||||||||
 Frog   808 EKRRYTSGIQTIVELFFEDVGRKHFPQVFAHLFIQSGSSQVHRSLNWADLIHRITSYLLQLLWPS 872

Human   839 NPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEV 903
            ||...|.||||.||||.|||:|::||.||||||||||.|||.:||||.|||.|||:||.||||||
 Frog   873 NPNFQFAECLMRNCQYTQLQEYVRLLLPWCQVNVGSCHFMLAQCYLVAGEGHKALDCFSQAASEV 937

Human   904 GKEEFLDRLIRSEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRT 968
            .:|:||::|||.|:||.|| ||||||::|||||:.:|||||||||||.||:||.|||:|||.|||
 Frog   938 EREDFLEKLIRVEEGESVS-PRLQYYNRVLRLLEDVGLPELVIQLATIAISEASDDWRSQAALRT 1001

Human   969 CIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIE 1033
            .|||||||:|||||||:|||||||:||||||||||||||||||||||||||||||||||||||||
 Frog  1002 RIFKHHLDMGHNSQAYDALTQIPDTSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIE 1066

Human  1034 SRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCL 1098
            |||||||||||||||||||||||||||||||||||||||||||||||||||:||.|.|||.||||
 Frog  1067 SRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLQKQVNSYLACLNCL 1131

Human  1099 RLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLA 1163
            |||||||||||||||||||:|||||||||:|||.:|.|::.|||||||.|||||..||:.|||||
 Frog  1132 RLIRPEYAWIVQPVSGAVYERPGASPKRNYDGESSAVPSSSQIEILELRDLEKEYVLAQTRLTLA 1196

Human  1164 QHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQA 1228
            :|:||..|:||||:|||||.||||||||||||||||||||.||.:|||||.|||:||.|||||||
 Frog  1197 KHNPSTAAIAGSSAAEEMVALLVQAGLFDTAISLCQTFKLGLTSIFEGLACKCIRLQQGGEAAQA 1261

Human  1229 EAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLIN 1293
            |||.|||||||::||||||||||||||||:.:||::|:.:|.|||||:|||||||||||||||||
 Frog  1262 EAWEWLAANQLATVITTKESSATDEAWRLMISYLDKYESKNTLYHHCIINKLLSHGVPLPNWLIN 1326

Human  1294 SYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQL 1358
            .||.:||||||||||.|||||||.:||.|||||:||||||||||:.|||||:.:||.|||:||.|
 Frog  1327 RYKAMDAAELLRLYLKYDLLEEAAELVLEYVDALLGKGHQYFGIQAPLSATSQLVWFPYSAIDHL 1391

Human  1359 LQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRR 1400
            ..|||||..|.||.|:..|:..|:::|.||:.|||.|  |::
 Frog  1392 RLALGENENNQHNQAILGKLQRKMDEYFQKLKKATDD--YKK 1431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUP160	NP_056046.2	Nup160	28..543	CDD:432020	349/517 (68%)
nup160	XP_031756356.1	Nup160	83..580	CDD:432020	344/496 (69%)