Protein Alignment MGA and H15

DIOPT Version :9

• Sequence 1: XP_005254300.1
• Gene: MGA / 23269
• HGNCID: 14010
• Length: 3115
• Species: Homo sapiens
• Sequence 2: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 93/236 - (39%)
• Similarity: 131/236 - (55%)
• Gaps: 26/236 - (11%)

Human    56 SPVKSKGKICLP---ADCTVGGITVT---LDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITG 114
            ||.:|..:...|   ..|....:|..   |:...:|::|:...||||:||.||||||..|...:|
  Fly   252 SPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSG 316

Human   115 ----LDSNLKYILVMDISPVDNHRYK--WNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQP 173
                :....:|.:::|:.|:|:.||:  ::...|..:|||:|....|::.||:.|.:......|.
  Fly   317 PLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQV 381

Human   174 VSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAVEVIQLNGPGV---------HTFTFP 229
            |||.|:|||||.:|:.|.::|:|||||.||:|||.......:     ||.         .||.||
  Fly   382 VSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSI-----PGSPKELQDMDHKTFVFP 441

Human   230 QTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQRD 270
            :|.|.|||||||..||:||||.|||||||||....:...||
  Fly   442 ETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRD 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MGA	XP_005254300.1	TBOX	74..264	CDD:238106	86/207 (42%)
		DUF4801	1041..1087	CDD:292677
		HLH	2475..2525	CDD:278439
H15	NP_608926.2	TBOX	276..475	CDD:238106	85/203 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750