|
Human 1 MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLK 65
|||||||||:|:|.||||||||||.||:||||:|||||||||.|:.||||||::|||.||||..|
Zfish 1 MEAGSVVRAVFEFLPSVSEELPLFTGDVIEVLSVVDEFWLLGNKDGVTGQFPTTFVESVTIPGTK 65
Human 66 EGERLFVCICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGARGFFPSSCVRELCLSSQS 130
.||.|:|||.:|.|.|..||||.|||:|..:....:.|::|.:.||:||.||.||::||.||.:|
Zfish 66 AGENLYVCINDFNSAEAGNLPLKRGDVVAAESSMDSVWMRGHNAWGSRGLFPVSCIKELELSGRS 130
Human 131 RQWHSQSALFQ---IPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRG 192
||...:||..| :|.:::|||||||.|.|||||||||||||||||||:||||||:|||:.|.|
Zfish 131 RQLSERSAAVQASELPPHALGQARALMNLHAQLDEELDFREGDVITIIGLPEPGWFQGELDNRTG 195
Human 193 IFPEGFVELLGPLR---------TVDESVSSGNQD-DCIVNGEVDTPVGEEEI---GPDEDEEEP 244
:||||||||||||| |:::.....|:| :.....|.|....|.|| ..||:|||.
Zfish 196 LFPEGFVELLGPLRSPLEEPEPQTLEQYPDYSNEDEERRAEEEKDEEPPEMEIQQCQEDEEEEEG 260
Human 245 GTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETM 309
..||:|||.|:||||.||||:|||:|||||:::||||||.:..|.|:||:||||:
Zfish 261 AIYGIALYEFRALEPGELDFDVGDRIRILASMDDGWLEGQIHSRRGVFPHRFVKI---------- 315
Human 310 ALPQEGSLARIPETSLDCLENTLGVEEQRHE--TSDHEAEEPDCIISEAPTSPLGHLTSEYDTDR 372
||.|..:|:| :.|.|.:.|.::..| |.|:.:.|.| |...||..:.
Zfish 316 ----EGQLQTVPQT--ETLINEISVPKREEECYTPDYTSAEED------------HTVPEYGQEL 362
Human 373 NSYQD----------------EDTAGGPPRSPGVEWEMPLA------------TDSPTSDPTEVV 409
:..|| ::..|....|.....|..:. .|.|....|:..
Zfish 363 SIQQDHTVWDLDYFERREEEQKENNGHNVHSDQSSQERRMTQNQSQVQPQERRRDRPPPPQTQPN 427
Human 410 NGISS----------------QPQVPFHPNLQ--KSQYYSTVGGSHPHSEQYPDLLPLEARTRDY 456
.|.|| :||:|..|:|. .::.||| |||....| |...|: |.:.
Zfish 428 RGSSSAHRSVQINRRSSPNMGRPQLPPRPSLHALSNRKYST--GSHASLRQ-PPPAPI---TMNQ 486
Human 457 ASLPPKRMYSQLKTLQKPVLPLYRGSSVS-ASRVVKPRQSSPQLHNLASYTKKHHTSSVYSIS-E 519
:..||. ||..........|...| .||.....:||.:.:.....|:....:....|| .
Zfish 487 SLNPPN------KTSPNSTWTRNNGKYASYNSRNPLSSKSSGEKNRQKKLTRHASVNDADIISGG 545
Human 520 RLEMKPGPQAQGLVMEAATHSQGD---GSTDLDSKLTQQLIEFEKSLAGPGTEP----------- 570
..|.:..||.||......:.:.|. .:.||::||:||||||||||.....|.
Zfish 546 SSEQQAWPQVQGSNGFPTSQTMGTLALSAKDLEAKLSQQLIEFEKSLPSHSNEATEQSRWEEVSG 610
Human 571 ---DKILRHFSIMDFNSEKDIVRGSSKLITEQELP-------------ERRKALRPPPPRPCT-- 617
:|:.|||||||::.|.||:||||....|:.|| ||||.||||||||..
Zfish 611 RLGNKVSRHFSIMDYSDENDIIRGSSHSSIERLLPSTSSPSGSASSSLERRKNLRPPPPRPRVLR 675
Human 618 -PVSTSPH-LLVDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSR-------HRPTCETL 673
|..|:.| ...:..:.|.| .||:||||.||.....||||:|...|. .....|.:
Zfish 676 PPAPTNTHWSQTNGRITPQP---YRPARPAPRPPPPCPHTNAVTPPTTSNPFYNSPDEEEIVEEM 737
Human 674 EK-----EGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQDESSRAETLE 733
|: |....|.|..:|.. :|:|:||:||::||||...:||..||:|:|||:||.:.||
Zfish 738 EEPEDVLEAEKEMEREQEQYR----LLLRLEEVEREIDMYSNTAQELQAMLDEEQDETSRQQALE 798
Human 734 DLKFCESNIESLNMELQQLREMTLLSSQSSSL-VAPSGSVSAENPEQRMLEKRAKVIEELLQTER 797
:|:||...:|:|.:|.|||:|||||:||..|| .:|:.:.::|:||.||||||.||||||||||.
Zfish 799 NLEFCSYTMETLTLEQQQLQEMTLLASQPKSLESSPASAANSEDPELRMLEKRTKVIEELLQTEH 863
Human 798 DYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAVGPVFLGHRDEL 862
|||:||:||::.|:.|:|:.||..|||:|||||:..||.:|::|...|:.:|::|.|||.::|:|
Zfish 864 DYIKDLQMCVKEIIQPLQKKQVQGIDFDGLFGNISSVIDLSRRLNKTLQDTDSIGQVFLSYKDQL 928
Human 863 EGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVM 927
|..|||||||||:||:|||.|||||.||||:.:.|..|:.:|.|||.||||||||||||||||||
Zfish 929 EDVYKIYCQNHDDAISLLETYEKDENIQKHVLECLEKLRGIYREWGKTNYINLGSFLIKPVQRVM 993
Human 928 RYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKL 992
|||||||||||:|||||.|:..|:.||:::|||||||||||||||||:||||||||.|::|||||
Zfish 994 RYPLLLMELLNTTPESHHDRQQLSEAVMSIKEINVNINEYKRRKDLVVKYRKGDEDRLIDKISKL 1058
Human 993 NIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACV 1057
::|||||||||||||||||||.:||||||.|::.||.||:||||||||||::|||||||||||.|
Zfish 1059 SMHSIIKKSNRVSSHLKHLTGISPQIKDEAFDDAEKRFRLQERLIKSFIRNISLYLQHIRESASV 1123
Human 1058 KVVAAVSMWDVCMERGHR-DLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLV 1121
||:||:|..|:..||..: |.|:|:|.||.|||:.||.||||||.|||:||.|||:||||||||:
Zfish 1124 KVLAAISFCDIYTERQQQMDPERFQRAHRCISDKQFTEFKERTEALVITPLTQLLNMFTGPHKLI 1188
Human 1122 QKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGY 1186
|||.|||||:.||.||||:||||:..||||:||||||||||||||||||||:.|:.|||:||.|:
Zfish 1189 QKRRDKLLDYDNCKERAERLKDKRVQEELQTARNNYEALNAQLLDELPKFHRAAEDLFTSCVRGF 1253
Human 1187 AEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPAT-KKPFE 1250
.:|..||:...|.:|.|||.|..:.|.||||:::|.|||:|||..||.|:||||:||.| :|.||
Zfish 1254 VQAQRDFISLTLGELTPLLQLSGLGGTEGNLVSLFQEEHTRVLDLLQSFSFFPENLPTTVRKTFE 1318
Human 1251 RKTIDRQSARKPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVI 1315
:||:::|..:|| ...|:|:||::|.||.||.||.||.|:|||||||||||||||:||||:||||
Zfish 1319 KKTLEKQYTKKP-QAPPNYVLQTDEHRAGLLVRYGPENLYQAERNFNAAQDLDVSVLEGDIVGVI 1382
Human 1316 KKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSG 1380
|::|||||||||||||||||||||||||||||||||.||.|:.|.||.||.:|.|||.|.||||.
Zfish 1383 KQQDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSQSDVSIESQSSNESGYGGSSPMFSRQNSN 1447
Human 1381 STLTFNPSSMAVSFTSGSCQKQ----PQDASPPPK-----ECDQGTLSASL--NPSNSESSP--- 1431
||||||..:..||||:.:.|.| |.:.|.|.| ...:.:|.... :|::.|.|.
Zfish 1448 STLTFNQETSTVSFTTATTQNQSNTRPNNESTPRKIRETSSNQRDSLEPGFRNSPNHKEVSETAI 1512
Human 1432 --SRCPSDPDSTSQPRSGDSADVARDVKQPT----------ATPRSYRNFRHPEIVGY-----SV 1479
||..|:|...|.....||.| .|...|| ....|.||.|:.....| |.
Zfish 1513 RNSREYSEPSHRSSTNHRDSVD--SDQNTPTNSRDRLDLSETDSSSSRNSRYEPSSRYQDSKASY 1575
Human 1480 PGRNGQSQDLVKGCARTAQAPEDRSTEPDGS-EAEGNQVYFAVYTFKARNPNELSVSANQKLKIL 1543
.....|:.| ..|..|..|...:...||:.. |.:|:|:|:|:|:|.||..||||:||||:::||
Zfish 1576 GSHQRQNGD-YSGQQRRPQYTPEEYIEPEPEPEIDGHQIYYALYSFSARCANELSISANQRVRIL 1639
Human 1544 EFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT 1577
||:|:.||.||||.|..|::||||||||||:|||
Zfish 1640 EFQDMNGNQEWWLGEAGGRRGYVPSNYIRKSEYT 1673
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