DRSC/TRiP Functional Genomics Resources

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Protein Alignment RHOBTB2 and Rac1

DIOPT Version :9

Sequence 1:NP_001153508.1 Gene:RHOBTB2 / 23221 HGNCID:18756 Length:749 Species:Homo sapiens
Sequence 2:NP_001261247.1 Gene:Rac1 / 38146 FlyBaseID:FBgn0010333 Length:192 Species:Drosophila melanogaster


Alignment Length:229 Identity:85/229 - (37%)
Similarity:119/229 - (51%) Gaps:48/229 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 98
            ::.||||||||.|||||.|:.:...||...:|      :|||:  |.|        .:..:||..
  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49

Human    99 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVG 161
            .::|.||||.|  |:.:.|..:|.::||.::|||:.||.|..:|:..||||::|.||..|:||||
  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVG 114

Human   162 CQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVAQFGIKDVFDNA 225
            .:|||| .|...:.:.|.....||    ..|  :|..:|||:| :.|.|.|.:.|.|:|.|||.|
  Fly   115 TKLDLR-DDKNTIEKLRDKKLAPI----TYP--QGLAMAKEIGAVKYLECSALTQKGLKTVFDEA 172

Human   226 IRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK 259
            ||:.|                      .|.|.||
  Fly   173 IRSVL----------------------CPVLQPK 184

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RHOBTB2NP_001153508.1 RhoBTB 35..229 CDD:133275 80/196 (41%)
RHO 39..230 CDD:197554 78/193 (40%)
BTB 280..>327 CDD:295341
BTB <443..492 CDD:197585
BTB <443..490 CDD:295341
BTB 513..615 CDD:279045
BTB 523..615 CDD:197585
Rac1NP_001261247.1 Rac1_like 3..176 CDD:206663 80/195 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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