Protein Alignment ACSBG1 and acs-15

DIOPT Version :10

• Sequence 1: XP_016877514.1
• Gene: ACSBG1 / 23205
• HGNCID: 29567
• Length: 748
• Species: Homo sapiens
• Sequence 2: NP_493856.3
• Gene: acs-15 / 187666
• WormBaseID: WBGene00019920
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 746
• Identity: 180/746 - (24%)
• Similarity: 288/746 - (38%)
• Gaps: 142/746 - (19%)

Human    41 LKTSSLT----------DRQP---LSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRL 92
            |||.||.          .|:|   |..:|:              .|.|...::.|.    |...|
 Worm    23 LKTGSLAAQDRGFFFGKRREPRCDLKNQSI--------------VQADGSRKSAWL----GDKPL 69

Human    93 RIDPSCPQLPYTVHRMFYEALDKY---------GDLIALGFKRQDK-----WEHISYSQYYLLAR 143
            |            |..|...|..|         |....|| ||..|     ||.|:|.|.:.::.
 Worm    70 R------------HESFIGILTTYAGIRRGPTVGGKEMLG-KRVMKNGKLEWEWITYEQAFEISD 121

Human   144 RAAKGFLKLGLK--QAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCAN 206
            ..::...|||::  ...::.|...|.|||..|.:.......:...||.....|...||...|...
 Worm   122 NVSQAIRKLGIEIGDKSNIGIYSKNRPEWVLSDMAIHNFSNVSVPIYDNIPNEDMHYITNLCEIP 186

Human   207 VIMVDTQKQLEKILKIWKQL-PHLKAVVIYKEPPPNKMA-------NVYTMEEFMELGNEVPEEA 263
            ::.||::.:..:::|....| ..||.:|.:.:......|       .:::.:||:|||.: .|..
 Worm   187 LMFVDSEDKTTQLIKDKTYLSKSLKYIVQFDKVSDEMKAMAESNNFQLWSFDEFVELGKK-HEHR 250

Human   264 LDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPL 328
            ..|   ...|.....:.:||||||.|||.||:..|:..|.   ....:....|.:.:..:|||||
 Worm   251 PHA---PPTPETLATISFTSGTTGRPKGAMLTHLNLCSTT---VACEEFEHVEGELDSYLSYLPL 309

Human   329 SHIAAQIYDLWTGIQWGAQVCFAEPD-ALKGSLVNTLREVEPTSHMGVPRV----WEKIMERIQE 388
            :|:..:...| ...:.|:::.|:..| ||   ||..::.:.|.:...||||    ::.:|.::|:
 Worm   310 AHVYERHCTL-AHFKIGSRIGFSRGDPAL---LVEDIQALAPRTFACVPRVLGKIYKSVMSQVQD 370

Human   389 VAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAA 453
            ...      :||:|.:.......:....|   |.....|.|..:|.|::..|| ...::....||
 Worm   371 KPV------KKMILNSAIAYKLYHYKMTG---KATRDTLVDKYILHKIQMILG-PNIKQFLIPAA 425

Human   454 PMMAETQHFFLG-LNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVN-------Q 510
            .....:..|..| ..|.:...|||:|||||..:.. ....|.|.|..:....:|||:       .
 Worm   426 KTDNSSMRFARGAFGIEILELYGLTETSGPTTIQL-VGDMLGSVGPPISCTSIKLVDIAELGYFV 489

Human   511 DAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGG 575
            |..| ||:.:.|..:..||......|..|..|:|::.|||.|:...:|.|.:..|...::....|
 Worm   490 DENG-GEVLVKGHNVTSGYYKDPKATASAFTEDGFMKTGDIGKFTPEGTLQLIDRRDNVLKLPQG 553

Human   576 ENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVG 640
            |.|.| .:.|::.:....:....:.|::.|   ..|......||:......|| |..:|
 Worm   554 EFVAP-DLTESLYISSKFVQQICVHGNKEK---PWLVAVVVPDPEYLASHANL-EHNIE------ 607

Human   641 SRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAA---RPYHIQKWAI--LERDFSISGGELGPTM 700
              ..|..|:.:      ..|:.|.:.|..::...   ||.|...:||  ....||...|...||.
 Worm   608 --GKTYEELCK------IPALAEDVLRDFVDLTKEHNRPRHEGVFAIHLTPIAFSPQNGLTTPTH 664

Human   701 KLKRLTV--------------LEKYKDGVSL 717
            |.||..:              :||.::|..|
 Worm   665 KNKRTAIAQFFKKQIVEMFDRIEKEEEGTEL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSBG1	XP_016877514.1	ACSBG_like	125..713	CDD:341256	156/634 (25%)
acs-15	NP_493856.3	Adenylate forming domain, Class I superfamily	107..683	CDD:473059	151/617 (24%)