Protein Alignment LARP4B and Larp7

DIOPT Version :10

• Sequence 1: XP_016871476.1
• Gene: LARP4B / 23185
• HGNCID: 28987
• Length: 1273
• Species: Homo sapiens
• Sequence 2: NP_524795.2
• Gene: Larp7 / 44900
• FlyBaseID: FBgn0260771
• Length: 595
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 109/537 - (20%)
• Similarity: 188/537 - (35%)
• Gaps: 182/537 - (33%)

Human   602 GDGDQGHENAALPDP-QESDPADMNALALGPSEYDSLPENSETGGNESQPDSQEDPRE------- 658
            |:|.:...:|..||| ..::||:.|              :.|....::.||.::..|:
  Fly    11 GEGQEPATSAEKPDPAAPTEPAEEN--------------SKEPAPEDASPDKKDGGRKRKRHLFN 61

Human   659 VLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVD 723
            .::..:||.....||:.|.:|...::.|.|||:......:.||.|:.||..|.:.|.:..|:::|
  Fly    62 SIRGQMEFYFGDANLSKDRFLRRYVEQDPYVPLEIFLTFNKIKTLTQDVQQIAKALSNSQLLELD 126

Human   724 EKGEKVR-----PNQNRCIVILREISEST-PVEEVEALFKGD---------------NLPKFINC 767
            |...||:     |:|       |::::.| .||.:.|....|               :||.:...
  Fly   127 ETELKVKRRTKLPDQ-------RDVNDKTLYVEALPANATHDWLKEVFSRYGPVAYVSLPHYPGT 184

Human   768 ----EFAYNDNWFITFETEADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLD 828
                |||     ||.||.....::|       ||.|      |:|:. .:::.|       .|.|
  Fly   185 KKIKEFA-----FIEFEKSGSLEKA-------VKAF------AQIQG-VLSVET-------DPSD 223

Human   829 V----SLYAQQRYATSFYFPPMYSPQQQFPLYSL---ITPQTWSATHSYLDPPLVTPFPNTGFIN 886
            :    |...||:.......|...:.|.:.|..:|   .|.:.....|......|....|:.....
  Fly   224 LASVRSFQQQQQIQQKAEQPQSEAEQVELPKRNLKREATDKDREEIHEVKRVKLEEGQPSETSTA 288

Human   887 GFTS------------------------------------------PAFKPAASPLTSLRQYPPR 909
            |.|:                                          |..:|:|..|..|    |:
  Fly   289 GETASETDAEGTAEASEQEDKTEATDGDEAAKKRRRKRKKKAIVDKPNIEPSALELKVL----PK 349

Human   910 SRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRS-------PQTRQ-AGQTRTRIQN 966
            :   |.|.:|:...:.:|                |:::..:|       ||.:| ....:|...|
  Fly   350 T---SWSSMRNKYLNLQR----------------RIVSEAKSKLWRENHPQNQQHPHHQQTSHPN 395

Human   967 -------PSAYAKREAG---PGRVEPGSLESSPGLGRGRK-------NSFGYRKKREEKFTSSQT 1014
                   |.|..:.|.|   |.....|::|::|...:.||       |.:|     .....|:::
  Fly   396 HPKPSQLPEAVKEEETGGEVPSDGGEGAVEAAPVPAKRRKAVHKMNMNFYG-----AGGVESTKS 455

Human  1015 QSPTPPKPPSPSFELGL 1031
            :.|:..:.|...:|.||
  Fly   456 EEPSQERTPLFKYEPGL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LARP4B	XP_016871476.1	LARP_5	657..731	CDD:153405	23/85 (27%)
		RRM_LARP5	736..812	CDD:410105	21/95 (22%)
Larp7	NP_524795.2	LA	57..135	CDD:128955	22/77 (29%)
		RRM1_LARP7	148..220	CDD:409732	21/97 (22%)
		RRM2_LARP7	471..548	CDD:409958	2/2 (100%)