|
Human 79 ELHPGDPAPGPAEDPKGDGEAGR----WEPSLSRKTATFKSRAPKKKYVEEHGAGSSGVAGAPEE 139
:|.|.:.:..|. |.|...|.| :.|.:.|.....||..|.: |.:
Worm 42 DLSPTNSSQAPT--PAGPIGAFRFSAFFNPDILRNLNIQKSSPPNQ----------------PSD 88
Human 140 RVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPPG------------- 191
.| ||..|...|:||.:| |.|.|..
Worm 89 DV--------------PPPQTSQPSSDTTAE--------------PLPSPAATRIHHPIPVQYNT 125
Human 192 -------STSGSYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGA 249
|.:.:..|......|||||...|::.|..|:....::|:.||....|... |:.|...
Worm 126 DLIAAATSVNSNVILVDWLGHRVLARVPPGVYQPGFVKTAYGNRDIIVQLDDGREAR-YDYVTSE 189
Human 250 G--VDVVLDATPPPG---ALVVGT--AVCTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSQ 307
. ..|:.|..|... .||..| ||...:|.....||...:......|..:.|:::....|
Worm 190 FNLTMVIADQAPSLSDLTTLVSNTILAVRLPLEKSETIYRTAELQSSNGNPPKFMVKVTNANYS- 253
Human 308 PGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPW-----EPETMLRKPPT-----------GP 356
|| |:|::|||||||| .|:.:....|| |.
Worm 254 -----SL----------------VSRANLRLLRPPWYEDLINPQRVSNSVPTSSMSLPSTSEDGR 297
Human 357 EEEQAEPGATL--------------------PPCPAALDPKQPEDAEVSKISFGGNL-------- 393
:...::...|| .|.|..:...| .|:..|..|.:
Worm 298 QNTNSQDNVTLLMALQQQQRRSQQLQHVINITPIPTPISTGQ----IVTHASPAGTVIVPVLPLQ 358
Human 394 -GTHCEEGEEKHPPALGTPALLP---------LPPPQLLSPPPKSPAFVGPGRPGEQPSPCQEGS 448
||..:|...| ..::.:...|| .|.|..:|.......||.| .|.|...|..
Worm 359 PGTSNQESSSK-TVSIDSDEELPESSNQDQSGEPSPTTVSSAASRSLFVNP----SQDSGIFEAD 418
Human 449 QGGSRSSSVASLEKGTAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMK 513
....:||...|: .||....:..|. ||::|||::|.|..||||||||||||||||::||.|
Worm 419 VDTPQSSMFHSI---NAPVCATKAMLD--QQRFKKGEIVTTQCGIRKKFNGKQWRRLCSKEGCNK 478
Human 514 ESQRRGYCSRHLSMRTKEMEG--LADSGPGGAGR-----------PAAVAAREGST--------- 556
|||||||||||||:::|...| :....||.:.. |::.|:|..:|
Worm 479 ESQRRGYCSRHLSLKSKPPHGHHMERGSPGSSKSDIFHPEPTVFLPSSTASRVPTTVNTAVFSGK 543
Human 557 ----EFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECE--AAVMLVSLGSSRSGTPS 615
.......|.::.....||.|..:..::: .|....||..: ..:::..:...|...|:
Worm 544 INPLSAPTSLLTDKNLPVQLVAERAHNLQQIL---QLGNVRFDNFQQIQQLLMQHVPQGRRHEPT 605
Human 616 FSPVSTQSPFSPAPS-PSPSPLFGFRPANFSPINASPVIQR--TAVRSRHLSASTPKAGVLTPPD 677
:.....|.|.|..| |:.|.:|...||.||.:.| |:.|: .|:..:.::|...
Worm 606 -AVSQANSAFCPPISLPNTSSMFNINPALFSQLTA-PLFQQHAQAILQQQINAQNS--------- 659
Human 678 LGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAGGGGAAPDFPKS 742
||| ...|.| |.|.|:.
Worm 660 ----------------------QTN------------NNSLKP---------------AEDEPEE 675
Human 743 DSLD-SGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQ 806
:..| :|.|:|| ..|
Worm 676 EDDDGAGSDNVS--------------------------------------------------VCQ 690
Human 807 RDSPVIVRNPDVPLPSKFPGEVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITV 871
:... |:.| .:..:.|.|.|...| .|..|.
Worm 691 KTEE---RSDD--------------DDDDSSGGGGGLTST------GSSNPN------------- 719
Human 872 PPAAPTAVAQPMPAFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNV 936
| :||.|| .|.: .|.|. :||
Worm 720 ---------------G-SSSNFQ---IHTT-------------------------SRSGE--SNV 738
Human 937 EPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSA 1001
.|.| ....::.|| ||.....||.|.
Worm 739 TPTS--------------------GGDQNQNQQ-------SNSRNSSAELAG------------- 763
Human 1002 DPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMS 1066
|..| ..|.|..|..|||.. |.:| |...|..:.||.|
Worm 764 ---------CDMS------QELSVETSDAGPPTL--------PSQP---SSIGSSVNSAFRS--- 799
Human 1067 PEIQLPLPPGKRRTQS-----LSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRAL 1126
.:.:.|.....|| :...|:...|:.|: .||.....:.|:|||||||||||||||.|
Worm 800 ---PVKIEPNDDYEQSSVKDVMDVKPEVFQSAKER-RRSKVSANEPHVRRPMNAFMIFSKRHRPL 860
Human 1127 VHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAK 1191
|||::||:||||||||||||||:|...:|.:||.||.|||||||||||||||..|::|
Worm 861 VHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQVKEAHFKAHPDWKWSTKEKK------- 918
Human 1192 PTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGP 1256
.:..|::.|..|..| :.:::.....:| ||..|
Worm 919 ------------IKSESLNTTPVALTP-LKNKVFDFDIRT---SDDLA----------------- 950
Human 1257 GSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYS--GPKPSTQYGAPGPFAAPGEGGAL 1319
::| :|| :..|..:|.|..|.:::. ..:.||| .:...|..|
Worm 951 -----KSF-------VDG----TALLSPMTPMTPGASAFRHLSSRDSTQ-SSTSSFDFP------ 992
Human 1320 AATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSE 1384
|.|.:.|:.::.|...|| :|.|.
Worm 993 ---GLPLMSPSLSAISMNTAS---------------------------------------ITSSP 1015
Human 1385 SGDSSGED--------PEGNKG----FGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGY 1437
:..|:... .:|..| |...:.|.::.|| |.||..| |: |
Worm 1016 ALSSATPSFQFDFESLKQGTAGVYPTFNPAMISTLVNSS-TPCRQIL----------PM-----Y 1064
Human 1438 GSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPM 1502
.:..||.....||:......:.|...|.| |:|..:..| .|.|||...|.:....
Worm 1065 NTDISSFFLPTASAFRVLNPTISSIIGGF--------SSADTVTTP---LGAPATTMAAMKMSFP 1118
Human 1503 DPATF---RRKRPESVGGLE----PPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAP 1560
:.|:. .:::.|||..|: .||.:.:.:| |:::..::
Worm 1119 ETASMLPQLQEKLESVSFLDQIKIEPGETPLPSP-----NVVRPTII------------------ 1160
Human 1561 APSLAYGAPAAPL---SRPAATMVTNVVRPVS--STPVPIASKPFPTSGRAEASPNDTAGARTEM 1620
|:..:.||.... ..||...:....||:. .|.|.:::|.| ..||....:...
Worm 1161 -PTAQFLAPTQQFVLQPTPAQLGIRRNKRPLREIDTDVTVSAKLF--------KRNDEQMDKLLA 1216
Human 1621 GTG-----SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYG 1680
..| :::|..:| .:|:: :.|.|.|.|..|.|....::. :|
Worm 1217 RVGFTEKFAQLPEFTP----KIYNE------------IPASPNLPTPFKTPGQDQSIF-----FG 1260
Human 1681 APAPPAVQFIAQ 1692
|...|..||:::
Worm 1261 ANFNPDQQFLSR 1272
| 
