Protein Alignment FLI1 and Ets96B

DIOPT Version :10

• Sequence 1: NP_002008.2
• Gene: FLI1 / 2313
• HGNCID: 3749
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_996290.1
• Gene: Ets96B / 42952
• FlyBaseID: FBgn0039225
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 83/270 - (30%)
• Similarity: 125/270 - (46%)
• Gaps: 59/270 - (21%)

Human   157 SFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPS 221
            |.::::....|..::..|....:..||..:..::.|.||.:   ..::|:.:|...||    |..
  Fly   419 SVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPSALRPN---VVDSTTSSDAELRL----DQF 476

Human   222 YDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQF 286
            |.|           :|::.|   ...|.||:.                        .|.:|||||
  Fly   477 YAS-----------NGISTS---SNGQAISQR------------------------RGSLQLWQF 503

Human   287 LLELLSD-SANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTK 350
            |:.||.: :.:||||.|.|...|||:.:|:|||||||.:|::|.||||||||:|||||:|.||.|
  Fly   504 LVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQK 568

Human   351 VHGKRYAYKF--DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSS 413
            |:|:||.|:|  |...:......|.|..|           .....||..::.....|:|....:.
  Fly   569 VNGERYVYRFVCDPDALFNMAYGHLTTGS-----------GKGDQHQLTLSLAKTPPTSGDSQTQ 622

Human   414 SFFGAASQYW 423
            |...|.|:|:
  Fly   623 SPRVAKSEYY 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FLI1	NP_002008.2	SAM_PNT-FLI-1	114..204	CDD:188883	8/46 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..271		11/61 (18%)
		ETS	280..363	CDD:197710	51/85 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..452
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	51/85 (60%)