Protein Alignment FLI1 and pnt

DIOPT Version :9

• Sequence 1: NP_002008.2
• Gene: FLI1 / 2313
• HGNCID: 3749
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 136/606 - (22%)
• Similarity: 181/606 - (29%)
• Gaps: 316/606 - (52%)

Human    77 RESPVD-----CSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNER-------------- 122
            :|.|:.     ||:|..|           ::.:.::.....||....||.:
  Fly   118 KEEPIHGCKDLCSLSDIS-----------DHEASLEVPTALPPLTPGTNRKVNEVLKASFASWEK 171

Human   123 ---RVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYNT 184
               :..:..||..||:|||..||.||..|:||:.::...|..|.|:.:..:.||.||..|..:..
  Fly   172 EVQKCNITKDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTG 236

Human   185 EVLLSHLSYLR----------------ESSLLA-------------------------------- 201
            ::|..||..|:                ||:..|
  Fly   237 DILWEHLDILQKDCEKPNEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMD 301

Human   202 -----------------------YNT--------------------------------------- 204
                                   |||
  Fly   302 YVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLP 366

Human   205 --------------TSHTDQSSRLS-----------------------------------VKEDP 220
                          :|:|:.||..:                                   :||:|
  Fly   367 PAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEP 431

Human   221 SYDSVRRGAWGNNMNS--------------------GLNKSPPLGGA------------QTISKN 253
            ...:...|.:|...||                    |.:.|.|.||.            .|||..
  Fly   432 GTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQ 496

Human   254 TEQR---------------------------------------------PQPDPY-----QILGP 268
            ..|.                                             |:..||     |.:||
  Fly   497 DHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGP 561

Human   269 TSSRL---------ANP---------------------------GSGQIQLWQFLLELLSDSANA 297
            ..:.:         .:|                           |||.|||||||||||.|....
  Fly   562 QPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQ 626

Human   298 SCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF-- 360
            |.|:|.|...|||:|||||||||||.||:||.|||:||||.|||||||||:.|..||||.|:|
  Fly   627 SFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVC 691

Human   361 DFHGIAQALQPHPTESSMYKY 381
            |.    |.|..|..|..:.||
  Fly   692 DL----QNLVGHTPEELVAKY 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FLI1	NP_002008.2	SAM_PNT-FLI-1	114..204	CDD:188883	33/177 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..271		24/178 (13%)
		ETS	280..363	CDD:197710	58/84 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..452
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	26/70 (37%)
		ETS	609..693	CDD:197710	57/83 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810