Protein Alignment FLI1 and fli1

DIOPT Version :10

• Sequence 1: NP_002008.2
• Gene: FLI1 / 2313
• HGNCID: 3749
• Length: 452
• Species: Homo sapiens
• Sequence 2: XP_021323256.1
• Gene: fli1 / 30619
• ZFINID: ZDB-GENE-980526-426
• Length: 474
• Species: Danio rerio
• Alignment Length: 454
• Identity: 358/454 - (78%)
• Similarity: 399/454 - (87%)
• Gaps: 10/454 - (2%)

Human     6 KEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREY 70
            :|||||||:|||||:..|.|||.|||.||||||:.||||.|||||:|||||||||||||||||||
Zfish    24 QEALSVVSEDQSLFEPPYAAAAPLPKTDMTASGTQDYGQTHKINPIPPQQEWINQPVRVNVKREY 88

Human    71 DHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERRVIVPA-----DP 130
            ||:||||||||||||.||:|:|||.|::.|||..|||||.. ||||||||||||||||     :|
Zfish    89 DHINGSRESPVDCSVGKCNKMVGGTEASQMNYTGYMDEKCA-PPPNMTTNERRVIVPAGEYCINP 152

Human   131 TLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLR 195
            :||:.:||||||:||||||.|.||||:.|.:.||||||||:|:||||.|::||||||||||:|||
Zfish   153 SLWSPDHVRQWLDWAIKEYGLQEIDTAMFHSTDGKELCKMSKDDFLRLTSVYNTEVLLSHLNYLR 217

Human   196 E-SSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQ-RP 258
            | ||.::|||.||.|||.||:.|:|.|||:|||..|.|||:||  |..|...:|::|||.:| ||
Zfish   218 ESSSSISYNTPSHADQSPRLAAKDDASYDAVRRTGWSNNMHSG--KGSPTVVSQSVSKNPDQPRP 280

Human   259 QPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGE 323
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
Zfish   281 QPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANAGCITWEGTNGEFKMTDPDEVARRWGE 345

Human   324 RKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYM 388
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||::.|:
Zfish   346 RKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESTMYKYPSELPYV 410

Human   389 PSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY 452
            |||||||||||||.|||.|||||||:|||..:.||:||.|||||||:||||.|:||||||||||
Zfish   411 PSYHAHQQKVNFVSPHPPSMPVTSSNFFGPTTPYWSSPPGGIYPNPSVPRHANSHVPSHLGSYY 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FLI1	NP_002008.2	SAM_PNT-FLI-1	114..204	CDD:188883	67/95 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..271		39/62 (63%)
		ETS	280..363	CDD:197710	81/82 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..452		15/18 (83%)
fli1	XP_021323256.1	SAM_PNT-FLI-1	131..226	CDD:188883	66/94 (70%)
		ETS	302..385	CDD:197710	81/82 (99%)