DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ZBTB43 and CG2129

DIOPT Version :9

Sequence 1:NP_001129248.1 Gene:ZBTB43 / 23099 HGNCID:17908 Length:467 Species:Homo sapiens
Sequence 2:NP_572449.1 Gene:CG2129 / 31741 FlyBaseID:FBgn0030008 Length:465 Species:Drosophila melanogaster


Alignment Length:348 Identity:72/348 - (20%)
Similarity:120/348 - (34%) Gaps:74/348 - (21%)


- Green bases have known domain annotations that are detailed below.


Human   155 FELGSGGHTDFPKAQELRDGENEEESTKDELS-SQLTEHEYLPSNSSTEHDRLSTEMASQDGE-- 216
            :|:|...:.|....:.:.:.::|:|..:...| .:..:|:.|.|.|..:...|..:...:|.|  
  Fly    97 YEIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQE 161

Human   217 ----------EGASDSAEF-----HYTRPMYSKPSIMAHKRWIH--------------------- 245
                      || ..||:.     |.|:...|:..:..|....|                     
  Fly   162 ECGMELDLDSEG-RHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDA 225

Human   246 -VKPERLEQACE--GMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEAEFDEQAD 307
             ||....|..||  |...|..|...|           |      ::.|...||:...|.|.....
  Fly   226 PVKSAAQEYKCEHCGKIYHGKYSLRQ-----------H------LKRDHDNGEEGGSAIFTCLEC 273

Human   308 ESNY-------DEQVDFYGSSMEEFSGER------SDGNLIGHRQEAALAAGYSENIEMVTGIKE 359
            |:..       :..|..:|.:.....|.|      ...:.:.|..|..:...:....:....|:.
  Fly   274 EAQLPRLRLLDEHMVQAHGGAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRH 338

Human   360 EASHLGFSATDKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHT 423
            ..:|.......|.:.|: ||.|..:|.....|:..|.|.||:||.||.|:|.....|..||.:|:
  Fly   339 MRNHGKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMHS 403

Human   424 GIKPYECNICAKRFMWRDSFHRH 446
            ..:|:.|::|...|..:...:.|
  Fly   404 TERPHVCSVCGATFSRQKGLYHH 426

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZBTB43NP_001129248.1 BTB_POZ_ZBTB43 8..128 CDD:349536
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..153
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 162..225 15/75 (20%)
C2H2 Zn finger 376..394 CDD:275368 5/18 (28%)
C2H2 Zn finger 402..422 CDD:275368 8/19 (42%)
zf-H2C2_2 414..437 CDD:404364 7/22 (32%)
C2H2 Zn finger 430..447 CDD:275368 4/17 (24%)
CG2129NP_572449.1 C2H2 Zn finger 296..316 CDD:275370 2/19 (11%)
zf-C2H2_8 323..411 CDD:292531 24/87 (28%)
C2H2 Zn finger 327..346 CDD:275368 2/18 (11%)
C2H2 Zn finger 354..374 CDD:275368 6/19 (32%)
zf-H2C2_2 367..389 CDD:290200 10/21 (48%)
C2H2 Zn finger 382..402 CDD:275368 8/19 (42%)
zf-H2C2_2 395..419 CDD:290200 8/23 (35%)
C2H2 Zn finger 410..430 CDD:275368 4/17 (24%)
C2H2 Zn finger 438..458 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.