Protein Alignment CDK19 and cdk19

DIOPT Version :10

• Sequence 1: NP_055891.1
• Gene: CDK19 / 23097
• HGNCID: 19338
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_001107512.1
• Gene: cdk19 / 100135368
• XenbaseID: XB-GENE-989176
• Length: 491
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 447/503 - (88%)
• Similarity: 465/503 - (92%)
• Gaps: 13/503 - (2%)

Human     1 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACR 65
            |||:||:||:||||:||:||||||||||||||||||||:||||||||||||||||||||||||||
 Frog     1 MDYEFKSKLSAEREKVEELFEYEGCKVGRGTYGHVYKAKRKDGKDEKEYALKQIEGTGISMSACR 65

Human    66 EIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKS 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 EIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKS 130

Human   131 LLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVV 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   131 LLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVV 195

Human   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMG 260

Human   261 FPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRIT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 FPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRIT 325

Human   326 SEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA 390
            |:|||||.|||||||||.|||||||||||||||||||:||||.:|| ||.||||||.||..||..
 Frog   326 SDQALQDLYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKTEKN-QQTQNQHQQQTATQQQTT 389

Human   391 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGP-VM 454
            . .|....||||:|||||.|.|       ||.|||||||||||.|.|||||:|||..||||| :|
 Frog   390 V-QQQQVQQQNSSQTNGTGGTA-------GAALQHSQDSSLNQGPQNKKPRMGPSANNSGGPSLM 446

Human   455 PSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY 502
            |||||||||||.|||:||||||.|:.:|||::|||||||   ||:|||
 Frog   447 PSDYQHSSSRLGYQSNVQGSSQPQNAMGYSTTSQQSSQY---HQSHRY 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK19	NP_055891.1	STKc_CDC2L6	18..335	CDD:270850	312/316 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..502		96/143 (67%)
cdk19	NP_001107512.1	Protein Kinases, catalytic domain	18..335	CDD:473864	312/316 (99%)