| Sequence 1: | NP_001446.1 | Gene: | FOXO3 / 2309 | HGNCID: | 3821 | Length: | 673 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001096419.1 | Gene: | foxo3 / 100125025 | XenbaseID: | XB-GENE-945072 | Length: | 653 | Species: | Xenopus tropicalis |
| Alignment Length: | 28 | Identity: | 8/28 - (28%) |
|---|---|---|---|
| Similarity: | 16/28 - (57%) | Gaps: | 2/28 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Human 55 HEKTMLDM--NKMIQSIIGSMQYSKELI 80 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FOXO3 | NP_001446.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..153 | 8/28 (29%) | |
| Required for mitochondrial import. /evidence=ECO:0000269|PubMed:23283301 | 80..108 | 1/1 (100%) | |||
| FH_FOXO3 | 157..239 | CDD:410835 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 231..302 | ||||
| Nuclear localization signal. /evidence=ECO:0000269|PubMed:17940099, ECO:0000269|PubMed:29445193 | 242..259 | ||||
| Mediates interaction with CHUK/IKKA and IKBKB/IKKB. /evidence=ECO:0000269|PubMed:15084260 | 300..673 | ||||
| FOXO_KIX_bdg | 432..511 | CDD:465228 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 536..587 | ||||
| FOXO-TAD | 606..644 | CDD:435506 | |||
| foxo3 | NP_001096419.1 | FH_FOX | 139..226 | CDD:469596 | |
| FOXO_KIX_bdg | 420..492 | CDD:465228 | |||
| FOXO-TAD | 587..625 | CDD:435506 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||