|
Human 42 GSEGGVAAFVDFVDIKSAQKAHNSVNKMGDRDLRTDYNEPGTIPSAARGLDDTVSIASRSREVSG 106
|..||.........|.:...:.||:| .|......|:|:.|.|...:|.:. ||
Fly 343 GRAGGATPLTTTSTITNNSFSSNSLN-------NTITTATPTMPTIASGAAGSVGLG------SG 394
Human 107 FRGG---GGGPAYGPPPSLHAREGRYERRLDGASDNRERAYE-HSAYGHHERGTGGFDRTRHYDQ 167
...| ..|.|.|...::.| .|..|.||....:. .:.:..|.|.|....|
Fly 395 AEAGVCSNSGTASGDILNVAA-------VLAAAVDNGVPTHPIRTRHNLHGRSTTSSSR------ 446
Human 168 DYYRDPRERTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRR 232
|.||||:.:.:
Fly 447 ------------------SHSRSPSSYSS------------------------------------ 457
Human 233 PERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGS-----GSRSRSSSSDSISSSSSTSS 292
.||.|.|.|||.. |.||.|.:| ||: |..||:.:|.:::|:||..|
Fly 458 -----SHSSSSSSHSSSH---------SHASSPVQS-SGNCAMAEGRSSRTVNSVTVTSNSSNPS 507
Human 293 DS--------------SDSSSSSSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFGIKVQNLP 343
.: |.||||||..|...|..:| :.:...|..:...|:|:|||
Fly 508 GTAVTVSSAGVGGGCGSSSSSSSSSSSSGSSCLTA----------NPVVHSEDNRPLAIRVRNLP 562
Human 344 VRSTDTSLKDGLFHEFKKFGKVTSVQIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEV 408
.||:|||||||||||:||.||||.|::.|.:.|||.||.|::.:|.||||..|..|.|||.:|||
Fly 563 ARSSDTSLKDGLFHEYKKHGKVTWVKVVGQNSERYALVCFKKPDDVEKALEVSHDKHFFGCKIEV 627
Human 409 TAWIGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVN 473
..:.|.:.| :|||||.:..:||:|||:|||||||||||..|..:||:.|:.||||::||||| .
Fly 628 EPYQGYDVE-DNEFRPYEAELDEYHPKSTRTLFIGNLEKDITAGELRSHFEAFGEIIEIDIKK-Q 690
Human 474 GVPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFC 538
|:..|||.||.||.||.||::|||||:||:||:||||||||||||||:||:...||:.:|...|.
Fly 691 GLNAYAFCQYSDIVSVVKAMRKMDGEHLGSNRIKLGFGKSMPTNCVWIDGVDEKVSESFLQSQFT 755
Human 539 RYGPVVKVVFDRLKGMALVLYNEIEYAQAAVKETKGRKIGGNKIKVDFANRESQLAFYHCMEK-- 601
|:|.|.||..||.:.:|||||::::.||||||:.:|..:...|::||||:||.|.|||...||
Fly 756 RFGAVTKVSIDRNRQLALVLYDQVQNAQAAVKDMRGTILRRKKLQVDFASRECQDAFYDKQEKQQ 820
Human 602 ---SGQDIR-DFYEMLAE--RREERRASYDYNQDRTYYE--SVRTP------------------- 639
||.:.| ..||..|. :...|.:|:..:|:.:..: .:.||
Fly 821 QQSSGSNPRFSRYESSASSLQSRSRASSFSRHQNNSNDDCSPINTPGGASSGISSASNLINQSTS 885
Human 640 -------------------------------GTYP------------------------------ 643
||.|
Fly 886 INISNIGTNACSAMPAPSLASAVVSCNVNASGTVPASTSMPSGVSSSSSSLPMSPAALAQRHRMV 950
Human 644 EDSRR----DYPARGREFYSEWETYQGDYYESRYYDD---------------------------- 676
.::|: |:...||..:...|...|....|..::|
Fly 951 RNARQTVDCDFNEVGRLRFRSSEEVSGGAGNSTQFEDVRCDSPVTARQGSAVNCFTGPTAAVGES 1015
Human 677 ---------------------------------PREYRDYRND-----------PYEQDIREYSY 697
|::.....|. |...|....|.
Fly 1016 IDGTLNNNQITGGAEGFTGSGGSILSRRRCGKTPKDLHPVHNQRIQLAEQVEECPSSGDEGVVSP 1080
Human 698 RQRER---------------ERERERFESDR----------------DRDHERRPIERSQS---- 727
|:|.: |...|....:: :|..|.|.:..:.|
Fly 1081 RKRIKMDYHHHHHHSNASGVESTGEHSSINKPSPLLLSNCDVIHDPLNRKSEIRRVSETPSGSPS 1145
Human 728 ---PVHL-----------RRPQSP------------------GASPSQAERL------------- 747
|.|| |||... |||....:.:
Fly 1146 IKFPGHLPSAPQSLMLSCRRPSIDVGALSALSSSSAFRHGIVGASSMDQQHMMNASAAAKRRRVT 1210
Human 748 -----PSDSERRLYSRSSDRSGSCSSLSPP----------RYEKLDKSRLERYTKNEKTDKERTF 797
||.|. ...|.|....|..|||:|. |..:|........:..|..|..|..
Fly 1211 TTMQQPSSSS-TTNSSSGSGLGGISSLTPADEYHHHVSRGRGHQLHSHHSHEASGGESADGSRPG 1274
Human 798 DP---ERVE----RERRL-IRKEKVEKDKTD----------------KQKR-------------- 824
.| ||.| ..||| ..:|:|.:...| :|.|
Fly 1275 TPLCDERPEVLPTEPRRLPPPRERVRERTRDVMWLPLPKFGVLFFQQQQSRSSGGGGAGNSYLQQ 1339
Human 825 -------------------------------------KGKVHSPS-------SQSSETDQENERE 845
.|....|| |.|...:|:|..:
Fly 1340 QLGGGSTGGLGCIGAASSSACSLNNSSLNASQGMGSCSGSTFLPSPSSRYWRSSSHHQNQQNNHQ 1404
Human 846 Q-----------------SPEKPRSCNKLSREKADKEGIAKN---------RL------------ 872
| ||.:||| ||...:|.:...:| ||
Fly 1405 QQSQQLHGSSSSNTCLMASPARPRS---LSSNSSDSDVPGQNAGGSPSLDERLRNFEENYERWSG 1466
Human 873 ----------------------------------------------------------------- 872
Fly 1467 GSSREHISGHTPSSATPSWQLSMHMNLSTGLNSHQTSSASGNSNSSSGTVSSSASNSRHKFLDID 1531
Human 873 ELMPCVVLTRVKEKEGKVIDH-------------------------------------------- 893
||.|..::..|..|:....|.
Fly 1532 ELQPSDIVKSVLAKKSVFDDDFQRLNKNQWYDPSSSDFALGSSSNIVTGSSLVANVSRHPGGPCS 1596
Human 894 ---------------TPV--------------------EKL------------------------ 899
||: ::|
Fly 1597 GNTSPALPNLAATKATPIIGNCSGGLGNSTGSKSAGLLQRLSSLSPMNSPQASMSPYNSPSPSPS 1661
Human 900 --------------------KAKLDNDTVKSSA-------------------------------- 912
.|.|...|..||:
Fly 1662 VGGVTACLGQLTKPAAPGTASAGLSGGTAASSSSPAANSGPTKGLQYPFPSHPPLPNTAAPPPAV 1726
Human 913 ------------------------LDQKLQV---SQTEPAKSDLSKLESV----RMKVPKEKGLS 946
|.:.|.| .|:.||:..|.|..|| .:..|....|.
Fly 1727 QPAPPPLPEMGKQSRLTGQSSGNNLTKSLSVPDGPQSSPARVQLQKSASVPGSTNVGAPSSLSLD 1791
Human 947 SHVEVVEKEGRL------------KARKHL-KPEQPA---------DGVSAVDL----------- 978
|....||....: .|..|: ||:|.. .|.|....
Fly 1792 STTASVETSASISSSTSNGNSSLTSAAIHVQKPQQSTFVEEEHTKKSGTSTSQSSSSSSKKISST 1856
Human 979 -EKLEARKRRFADSNLKAEKQKPEV---------------KKSSPEMEDARVLSKKQPDVSSREV 1027
:||.::....::|:.|.:|..... |.::|.:||....:....|.:.:..
Fly 1857 HDKLHSKHNNRSESDKKIKKSDKNASSSDKRKNSSTSQSSKSATPRIEDDSSEADDTADKAEKNQ 1921
Human 1028 ILLREGEAERKPVRKEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELA 1092
...:| :.||:..|::.|:::.::.:.|| |..|| .|...|.:|:..|..
Fly 1922 RHEKE-KKERQEKREKDLRKQVEREEKDR-------KAQQE---------EREKEDRKAKEEEKE 1969
Human 1093 GESVENQEVQSKKPIPSKPQLKQLQVLDDQGPERE----DVRK--------NYCSLRDETPERKS 1145
.|..:..:...:|....:.:|::.:..|.:..|:| |:|: ....|||:....|.
Fly 1970 REREKKAQEDREKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKE 2034
Human 1146 GQEKSHSVNTEEKIGIDIDHTQSYRKQMEQSRRKQQMEME-----IAKSEKFGSPKKDVD----- 1200
.:||. ..|:::..:.|..:...::.|||||...:|.| :.:...:...|.|:.
Fly 2035 MREKE---QREKELHREKDQREREHREKEQSRRAMDVEQEGRGGRMRELSSYQKSKMDIAGEASS 2096
Human 1201 ------EYERRSLVHEV-----GKPPQDVTDDSPPSKKKRMDHVDFDICTKRERNYRSSRQISED 1254
::.:.:.:..: |..|...:|::|..:.:::.... ..|....|.|.|.|..
Fly 2097 LTAIDCQHNKENAMDTIAQGTPGASPSTPSDNTPKERSRKLSRNS----PVRLHKRRLSSQESNH 2157
Human 1255 SERTGGSPSVRHGSFHE--DEDPIGSPRL-----LSVKGS-----PKVDEKVLPYSNITVREESL 1307
|...|||.. ||.|: .||.:...|: :||..| .:.|.|....|:....:.|.
Fly 2158 SAGGGGSCG---GSSHQIHHEDYVKRIRMENSQNISVHSSNQRLNDRRDSKEHKSSSFKEDKNSS 2219
Human 1308 KF--NPY-------DSSRREQMAD-----------------------MAKIKLSVLNSEDELNRW 1340
.. .|: .||:.....| :::.|.::..||:||...
Fly 2220 SHISRPHGCGGSSASSSKHHHRRDKHHQKGSASSIETNSSIEVVVDPISQTKHNLNTSEEELQSH 2284
Human 1341 DSQMKQDAGRFDVSFPNSIIKRDSLRKRSVRD------LEPGEVPSDSDEDGEH--KSHSP--RA 1395
..:.:::...|. |..|| .|.|.:|.|| .:...|...::.|.|| :.|:| |.
Fly 2285 QPKREKEREHFS-SHANS----SSSRHKSKRDHHHHREKKRHSVAESTNTDEEHTPQQHNPHRRI 2344
Human 1396 SALYESSR---LSFLLRDREDKLRERDERLSSSLERNKFYSFALDKTITPDTKALLERAKSLSSS 1457
||....|. .|........||..:..| .|:||.. |...|:.....:|:|..:...|||:
Fly 2345 SAAGSGSAGELSSAATNTSSGKLHHQHHR--RSVERKS--SRGSDEGHHSSSKSLRAKLMMLSSA 2405
Human 1458 REEN-------WSFLD----------WDSRFA----NFRNNKDKEKVDSAPRPIPSWYMKKKKIR 1501
..:: .|..| :|...| |.:...:::|:.:....:.....|||: .
Fly 2406 DSDDTDDASKKHSIFDIPDDCPNVSMYDKVKARSCKNMQRQAEEKKIKAKFSQLKQSRAKKKR-S 2469
Human 1502 TDSEGKMDDKKEDHKEEEQERQELFASRFLHSSIFEQDSKRLQHLERKEEDSDFISGRIYGKQTS 1566
|..:|..|.:.|| ::........|..|:...|..:.|.....|..|...||| ..:|.|.:
Fly 2470 TSYDGDSDTEFED-RQHRNSGSSSFHGRYPGLSSSDDDDDEETHQRRISSDSD----AEHGGQDN 2529
Human 1567 EGANSTT-------------------DSIQEPV---VLFHSRF---------------------- 1587
:||::.. ||.::.: |:.||.|
Fly 2530 QGASTLADANRVRQMQQNLRRLCDGDDSSEDEIRRNVMKHSHFGKRNSNSTRIASDSESQSQPAP 2594
Human 1588 -------------MELTRMQ-----QKEKEKDQKPKEVEKQE-DTENHPKT-------------- 1619
.|:.|.| ||.|.:......:|::: .||...||
Fly 2595 DLTIKQEHPIAPAQEIKREQLSDEEQKFKSRHDSNSSIEERKLKTEREIKTELGDFYNSSEYTYT 2659
Human 1620 -------PESAPENKDSE-------------LKTPPSVGP--PSV-------------------- 1642
||:..::|.|: .:||..:.| ||:
Fly 2660 GKLKEYSPETRKKHKKSKRRLKSSSTADTSAAQTPLVMTPLTPSIFDVHSSSECKTKFDNFDDLK 2724
Human 1643 --------------------------------TVVTLESAPSA---------------LEKTTGD 1660
|..|:.::|:. |:|:...
Fly 2725 TECSSIPLEISAGERRKHKERKEKKREKLRNMTEATVPNSPTTNDTSSEKLSKEERHRLKKSKKS 2789
Human 1661 KTVEAPLVTE---EKTVEPAT-VSEEAKPASEPAPAP---------------VEQLEQVDLPPGA 1706
|:::....|: .....|:| .|..|.|.|.|:.|. :...|:...|..|
Fly 2790 KSMDNSCNTKIYNSSGAHPSTSPSLPATPTSAPSTAQTSKRGEDKMEFIFGIISDEEESQFPEQA 2854
Human 1707 DPDKEAAMMPAGVEEGSSGDQPPYLDA-------KPPTPGASFSQAESNVD-PEPDSTQPL---- 1759
:.:|: ::|:.| .::| |.:.| :|.||.:...:|...:. .||:..|.|
Fly 2855 ETNKD--IIPSSV--STTG---PIVSAALQTYKQEPSTPNSKNEEAHIQLTVHEPEQQQQLERSR 2912
Human 1760 -------SKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAK--- 1814
|..|.:.....| |.||...........||..:.:.:.:....:|..||...|.:
Fly 2913 LSGGSSSSSHADRERHRRE-KREKKRREKSQREQQNQIHQKSSKVETKVDDDNSVDMDEAGRALE 2976
Human 1815 -------DKKPNKSKRSKTPVQAA-------------------AVSIVEKPVTRKSERIDR---- 1849
|.|| .....||..|| :|.:.::.| |||:.::
Fly 2977 AQLMSDFDTKP--ISEEATPSTAATYRSDMTDVFRFSDNEDNNSVDMTKQGV--KSEQQEQHKSK 3037
Human 1850 -EKLKRSNSPRGEAQKLLELKMEAEKITRTASKNSA-----------------ADLE-------- 1888
:|.|:..|...:.:|||: :...|.:...||.:|| |||:
Fly 3038 DKKKKKKRSKEEKQEKLLQ-QQRRESLPNVASTSSAPPTPGKLTVNVQAASKHADLQLDAKHISS 3101
Human 1889 ----HPEPSLPL------------------------------SRTRRRNVRSV--------YATM 1911
.|.||||. ||.:.|.:..: .:|:
Fly 3102 PPVCKPSPSLPCLIGDDDDDALHTPKAKPTTPSSRGNDGLTPSREKPRLISPIPKTPTIANSSTL 3166
Human 1912 GDHENRSPV------------------------------KEPVEQPRVTRKR----------LER 1936
......:|| ..|.......:|: |:.
Fly 3167 STQSAETPVSSGTVISSSALATTPTSSTAAGVSAAPGLDNSPTSASAQCKKKESFIPGFDGQLDD 3231
Human 1937 ELQEAAA-----------------------VPTTPRRGRP------PKTRRRADEEEE------- 1965
.:.|:|. |.:.||..:| .|:|....:||.
Fly 3232 RISESAVQSISAEFNSTSLLDNIADEPKIPVASPPRATKPLDKLEESKSRVTISQEETESAVSAL 3296
Human 1966 ------------------------NEAKEPAETLKPPEGWRSPRSQKTAAGGGPQG--KKGKNEP 2004
||.:.|...:..|:...:..::.....|.|.. ::.:.||
Fly 3297 LGESFGTSSTTDYSLDGMDEMSSVNELETPTLVIAEPDEEAALAAKAIETAGEPASILEEPEMEP 3361
Human 2005 KVDA---TRPEATTEVGPQIGVKESSMEPKAAEE---------EAGSEQ-KRDRK-DAGTDKNPP 2055
:.:| ..|||..|..|.:.|.:.....||.:. :|.:.| :||.: |..|::||.
Fly 3362 EREAEPDPDPEAEIESEPVVEVLDPEELNKAVQSLKHEDMMDIKADTPQSERDLQIDTDTEENPD 3426
Human 2056 E---TAPV----EVVEKKPAPEK----NSKSKRGRSRNSRLAVDKSASLKN-------------- 2095
| :.|. |.|:...:||| ||.:.|..:......|:....|.|
Fly 3427 EADSSGPSLKIDETVQSSSSPEKSISNNSPTPRETANIDIPNVESQPKLSNESTPQPSVITKLPF 3491
Human 2096 ------VDAAVSPRGAAAQAGERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVS 2154
|.|.:.| ||.|.|.| ..|:|:...|.| |.
Fly 3492 LDTPKTVPAGLPP-----------------SPVKIEPP-----TISKLQQPLVQP--------VQ 3526
Human 2155 ASGPSPEAT------QLAKQMELEQAVEHIAKLAEASASAAYKAD------------APEGLAPE 2201
...|:|.:| .....::|...:...:..:.|||:|:..|. .|:...|:
Fly 3527 TVLPAPHSTGSGISANSVINLDLSNVISSCSNTSAASATASASASISFGSPTASQNAMPQASTPK 3591
Human 2202 DRDKPAHQASETELAAAIGSIIN-----DISGEPENFPAP----------PPYPGESQTDLQPPA 2251
.......||..|: |:|. .|..:..:|..| |..||.....::.|:
Fly 3592 QGPITPQQAIRTQ------SLIMQPPTISIPEQTPHFAVPQMVLSPQSHHPQQPGTYMVGIRAPS 3650
Human 2252 GAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDPS------------------------ 2292
....|.....|:.....|..: :...||.|:.|.|.
Fly 3651 PHSPLHSPGRGVAQSRLVGQL------SPVGRPMVSQPSPQQQVQQTQQQHALITSPQSSNISPL 3709
Human 2293 AGPTDTKEARGNSSETS---------HSVPEAKGSKEV--------------------------- 2321
|.||....:..||..|| ..||:....|.|
Fly 3710 ASPTTRVLSSSNSPTTSKVNSYQPRNQQVPQQPSPKSVAEVQTTPQLMTIPLQKMTPIQVPHHPT 3774
Human 2322 ---EVTLVRKDKGRQKTTRS----------------RRKRNTNKKVVAPVESH------------ 2355
:|..|:..:..|....| ..:.....:|:|.:.:|
Fly 3775 IISKVVTVQPQQATQSQVASSPPLGSLPPHKNVHLNAHQNQQQPQVIAKMTAHQHQQHMQQFMHQ 3839
Human 2356 ----------------------------VPESNQAQGESPAANEG------TTVQHPEAPQ---- 2382
:.:.:|||.:....|:. ...|||...|
Fly 3840 QMIQRQQHMQQQQLHGQSQQITSAPQHQMHQQHQAQQQQQHHNQQHLNQQLHAQQHPTQKQHQAQ 3904
Human 2383 -------EEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEISVEER-------------------- 2420
::.||::.|....|:.............|.|:::.:.:
Fly 3905 QQFNQQIQQHQSQQQHQVQQQNQAQQQHLSQQQHQSQQQLNQQHQAQQQQLQQIQKLQQMHGPQQ 3969
Human 2421 --------------TPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIESDPVTPPSDPSIPIPT 2471
|...||...:...|.:..|..:.|| .:..|.|..| .|
Fly 3970 QQKSPQGVGHLGGSTSIFASQQHNSQLPARGVPQQQHPQ------QLSHSSPCKP--------NT 4020
Human 2472 LPSVTAAKLSPPVASGGIPHQSPPTKVTEWITRQEEPRAQ-----------STPSPALPPDTKAS 2525
|.||... :.||.....:...|.|.: :|:.|..| |:|...||..|..:
Fly 4021 LVSVNQG-VQPPAILTRVGSHSQPNQ------QQQLPHQQSSSGHPHQKQLSSPGANLPLQTPLN 4078
Human 2526 DVDTSSSTLRKILMDPKYVSATSVTSTSVT-TAIAEPVS----AAPCLHEAPPPPVDSKKPLEE- 2584
.:..:. ||::....|:...|...... .||..|.: :.|..|..|.|.:.::|..|.
Fly 4079 VIQNTP----KIIVQQHIVAQNQVPPPQTQGNAIHYPQNQGKDSTPPGHVEPTPAMSAQKTSESV 4139
Human 2585 ---KTAPPVTNNSEIQASEVLVAADKEKVAPVIAPK-----------------------ITSVIS 2623
:|..|.|..:.|.|:.|.....:|.:..:..|| |.|||.
Fly 4140 SVIRTPTPTTGLAVISANTVGSLLTEENLIKISQPKQDELIEQDSKEVDSDYWSAKEVNIDSVIK 4204
Human 2624 RMP---VSIDLENSQKITLAKPA----PQTLTGLVSALTGLVNVSLVPVNA------------LK 2669
::. .|.|.:.:.::....|| ||.....::..|.|...|:...|: ..
Fly 4205 KLDTPLASKDAKRAVEMQAIAPAPIPNPQPGNQSMAQETALPTTSMSVNNSNDHDTEDETETRQL 4269
Human 2670 GPVKGSVTTLKSLVSTPAGPVNVLK------GPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAA 2728
.|.|..:.| |..|.|.....| |...|...|:|.:|. ....|.::...||. |..
Fly 4270 PPAKPPIPT----VGRPPGRGGSAKRGRQPRGAKKVGGFPLNSVTA-APPGVDSLVVQPGD-NGV 4328
Human 2729 ASAVNATASAVTVTAG-----------------------------AVTAASGGVTATTGTVTMAG 2764
.:.:....:| .||.| .||:|:......| .:..:.
Fly 4329 QTRLRKPVTA-PVTRGRKGRPPRNLLLQQQQLQQQQLDIQRKGMEMVTSATSSTPLPT-PIPTSS 4391
Human 2765 AVIAPSTKCKQRA--SANENSRFHPGSMPVIDDRPADAGSGAGLRVNTSEGVVLLSYSGQKTEGP 2827
.:.|...|.:.:| .|.|.:: ...:|.|.:.:......|.:...|
Fly 4392 VLTAAEKKARNQALTQAQEQNQ-------------------VASQVGTGQDIYEFHEDGGEEPKP 4437
Human 2828 QRISA--------------KISQIPPASAMDIEFQQSVSKSQVKPDSVTASQPPSKGPQAPAGYA 2878
:.||: .|::..|:.....|.:|::.:.|.:...|.::..|..|..:.: .
Fly 4438 KTISSVAPSAEDQRPRLILTINKTQPSIKNISEMEQTIQQQQQQQSEVISNTDPIGGDNSES--C 4500
Human 2879 NVATHSTLVLTAQTYNASPVISSVKADRPSLEK-PEPIHLSVSTPVTQGGTVKVLTQGINTPP-- 2940
|......| ..|.||.:::. .|.:..:.:||. ||...|.:|..|||
Fly 4501 NTRKSRRL--------------QEKEDRSTVDDIIEDVVRNTNTPT---GTGPHLPKGAQTPPRR 4548
Human 2941 ------------VLVHNQL----------------------VLTPSIVTTNKKLADPVTLKIET- 2970
|.:.|.: |...:.......||.|....:|:
Fly 4549 SGRNAQAKKTDAVQIINAVGRPRRSKDRKTIGEQTANLIEEVTASNATVAASHLAPPEGAGVESH 4613
Human 2971 ------KVLQPANLGSTLTPHHPP-----ALPSKLPTEVNHVPSGPSIPADRTVSHLAAAKLDAH 3024
|.::|. |.:||...| |.|..:|... .||..|::|.......:|||:::::
Fly 4614 VPQLDAKEVEPV---SVVTPISTPAPVSVAAPVTVPVPA-MVPVKPTMPQHPKKKAIAAAEIESY 4674
Human 3025 ----SPRPSG-------PGPSSFPRASHPSSTASTALSTNATVMLAAGIP-------------VP 3065
|..||| ..|::.......:...|.||....|.::.||:| .|
Fly 4675 QAINSSIPSGGLPMHQTAAPATQKITGGVADAVSKALVDPVTGVITAGMPQGKEGNLPAATAAAP 4739
Human 3066 QFISSIHPEQSVIMPPHSITQTVSLSH-----LSQGEVRMNTPTLPS-----ITYSIRPEALHSP 3120
...|: |.....||..:.......| ..|..:::||..:|| ||...:...|.:.
Fly 4740 ANSSN---EDGQAAPPPQLQHQQQQQHPQQPPQQQANLQINTTLIPSGLPNPITALGKSVQLETS 4801
Human 3121 RAPLQPQQIEV----RAPQRASTPQP---APAGVPALASQHPPEEEVHY--HLPVARATAPVQSE 3176
.|.|..:.:.| .|.|.....|| |||..|.:..|:|....:|: |..| |...|:::.
Fly 4802 AAALLNKPVSVLVKGNASQVIQQQQPQIVAPAKQPIILQQNPLPTVLHHAQHTTV-RPPQPLKAH 4865
Human 3177 VLVMQSEYRLHPYTVPRDVRIMVHPHVTAVSEQPRAADG-------------------------- 3215
||..: ::::..:.|...||::.|:.|..
Fly 4866 VLNRE-----------KNIQQQLTPTKQAVAQPPQHAPHSGHMLLTDTAGNQQLVQPQIIARHLQ 4919
Human 3216 -----VVKVPP----ASKAPQQPGKEAAKTPDAKAAPTPTPAPVPVPVPLPAPAPAP---HGEAR 3268
.|.||| :..:|:.|.::....|.|..:| ....|..|.:...|.|..| |..:.
Fly 4920 QQQHLQVNVPPPTAHSPHSPRIPSQQQQLGPGASISP-QQQQPQTVVIKQAASAAQPQILHVVSS 4983
Human 3269 ILTVTPSNQLQGLP----------------------LTPPVVVTHGVQIVH-------SSGELFQ 3304
..:|.|..|.|.|| |||.:......|..| ..|...|
Fly 4984 KASVVPQPQQQQLPPTSSTGPHLQLAKPNYSYAPTVLTPTLPAVQQQQQQHLYKQNNQQKGAQIQ 5048
Human 3305 EYRYGDIRTYHP--------PAQL---THTQFPA-------------------ASSVGLP----- 3334
...:|.|...|| ||.| .|...|: ..|||.|
Fly 5049 MPPHGIIMPTHPGMLLQQKLPAHLQPQQHQLNPSPPPGKPNPVLHGLQSGQIMPGSVGSPPPVSA 5113
Human 3335 SRTKTAAQ------------------------------------GPPP------------EGEPL 3351
:..|||.| |.|| .|...
Fly 5114 AVLKTAQQQVNSVVPVAGIRTAIPNISPQSQPRVSPLVLPPGISGVPPFDASLHDLGAYVSGRRT 5178
Human 3352 QPPQPVQSTQPAQPAPP---------------------------------CPPSQLGQPGQ-PPS 3382
|.|.|.. |.|.|..| .||.:|.:||. ||.
Fly 5179 QSPPPAH--QQASPITPNDSTYRGVTASRDFMLYQHHLMRGGDYDDKMGSSPPLELRRPGSGPPR 5241
Human 3383 SKMPQVSQEAKGTQTGVEQPRLPAGPANR---PPEPHTQV-QRAQAETGPTSFPSPVSVSMKPDL 3443
:.....|.::...:|..:.|::.....:. ||...::: .|...::|......|
Fly 5242 TIAVPHSLQSPQDRTAADSPQMAQVYVHNTRIPPAHFSEIASRGLYDSGALQLEPP--------- 5297
Human 3444 PVSLPTQT----APKQPLFVPTTSGPST---PPGLVLPHTEFQP------------------APK 3483
|...||.| .|:| :|..|..|. ..|.|.|.:...| |..
Fly 5298 PAHRPTATISVVVPQQ---MPAVSSGSPFIGRDGSVQPGSHHHPGKAMDMQLDEMDRMSMIAAVV 5359
Human 3484 QDSSPHLTSQRPVDM-------------------VQLLKKYPIVWQGLLALKNDTAAVQLHFVSG 3529
|....||....|..| |.||::||::||||||||.|.||||:|||.|
Fly 5360 QQQQEHLPPALPAGMELASQQAPPAMAPPPGDSLVTLLQRYPVMWQGLLALKTDQAAVQMHFVHG 5424
Human 3530 NNVLAHRSLP--LSEGGPPLRIAQRMRLEATQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQT 3592
|..:|..||| :....|.||||||||||.|||||||::|.|:.::|:|||||||||..||:..:
Fly 5425 NPNVARASLPSLVETNTPLLRIAQRMRLEQTQLEGVAKKMQVDKEHCMLLALPCGRDHADVLQHS 5489
Human 3593 ESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHL 3657
.:|:..||||||.|.||||:|:|.|||.|.|||:.|||.|:|:..:|.|.||||...::.:: ||
Fly 5490 RNLQTGFITYLQQKMAAGIVNIPIPGSEQAAYVVHIFPSCDFANENLERAAPDLKNRVAELA-HL 5553
Human 3658 MIVIASV 3664
:||||:|
Fly 5554 LIVIATV 5560
| 
