DRSC/TRiP Functional Genomics Resources

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Protein Alignment IGSF9B and DIP-zeta

DIOPT Version :9

Sequence 1:NP_001264214.1 Gene:IGSF9B / 22997 HGNCID:32326 Length:1437 Species:Homo sapiens
Sequence 2:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster


Alignment Length:401 Identity:99/401 - (24%)
Similarity:151/401 - (37%) Gaps:99/401 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    10 ASVIGTRGLAAEGAHG---------LREEPEF------VTARAGESVVLRCDVIHPVTGQPPPYV 59
            ::|:|:.|:...|...         :.|||||      ||..||.:|.|.|.|.:  .|.   |.
  Fly    84 STVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKN--LGS---YK 143

Human    60 VEWFKFGVPIPIFIKFGYYPPHV---DPEYAGRASLHDKAS---LRLEQVRSEDQGWYECKV--L 116
            |.|..|.....:.:.     .||   :|..:.....||:..   |.:..|..||:|.|.|::  :
  Fly   144 VAWMHFEQSAILTVH-----NHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTV 203

Human   117 MLDQQYDTFHNGSWVHLTINAPPTFTET-PPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLL 180
            ....|:.        :|.:..||...:: ....:..:||.:|::.|.|.|:|:||:.|.::....
  Fly   204 TAKTQFG--------YLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSR 260

Human   181 GASGKYQV----SDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTT-----HLLVQGPPFIVSP-- 234
            .|..|..:    ...:|.:|.:||.|.|||.|    |....|..|     .:.|..||.::.|  
  Fly   261 IAINKNHIVNEWEGDTLEITRISRLDMGAYLC----IASNGVPPTVSKRIKVSVDFPPMLLIPHQ 321

Human   235 ----PENITVNISQDALLTCRAEAYPGNLTYTWYW-QDENVYFQNDLKLRVRILI-------DGT 287
                ||...|.|.      |..||:|.:|.   || :.|.....:..|.:|...:       ...
  Fly   322 LVGAPEGFNVTIE------CFTEAHPTSLN---YWTRGEGPIIHDSHKYKVEATVGLPAYKTHMK 377

Human   288 LIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEP 352
            |.|..|...|.|.|.||..|..|.: .....|.|.||....:.        ||:           
  Fly   378 LTIINVSSGDDGIYKCVAKNPRGET-DGIIRLYVSYPPTTASS--------GIY----------- 422

Human   353 PATVVKWNKDG 363
             :|...|.::|
  Fly   423 -STDTHWGENG 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IGSF9BNP_001264214.1 IG_like 30..115 CDD:214653 28/96 (29%)
Ig 41..115 CDD:143165 21/79 (27%)
I-set 139..225 CDD:254352 25/95 (26%)
IGc2 153..210 CDD:197706 21/60 (35%)
I-set 229..321 CDD:254352 27/105 (26%)
Ig 235..321 CDD:299845 25/93 (27%)
IG_like 331..414 CDD:214653 5/33 (15%)
Ig <353..414 CDD:299845 3/11 (27%)
IG_like 426..505 CDD:214653
Ig 442..505 CDD:299845
FN3 510..601 CDD:238020
FN3 617..699 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 758..817
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 911..1081
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 27/113 (24%)
Ig 130..200 CDD:143165 21/79 (27%)
I-set 226..310 CDD:254352 24/87 (28%)
IGc2 233..298 CDD:197706 22/68 (32%)
Ig 313..410 CDD:299845 28/106 (26%)
IG_like 325..410 CDD:214653 25/94 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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