DRSC/TRiP Functional Genomics Resources

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Protein Alignment IGSF9B and DIP-iota

DIOPT Version :9

Sequence 1:NP_001264214.1 Gene:IGSF9B / 22997 HGNCID:32326 Length:1437 Species:Homo sapiens
Sequence 2:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster


Alignment Length:328 Identity:78/328 - (23%)
Similarity:132/328 - (40%) Gaps:61/328 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    29 EPEF------VTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYA 87
            :|:|      .|...|...:|.| |:|.:..    :.|.|.:......:.|:     .||..: .
  Fly    30 DPKFSGPINNSTVPVGRDALLTC-VVHDLVS----FKVAWLRVDTQTILSIQ-----NHVITK-N 83

Human    88 GRASL----HDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTE-TPPQ 147
            .|.|:    |....|::..|:..|:|||.|::     ..|.. .....:|.:..||...: ...|
  Fly    84 HRISISHTEHRIWQLKIRDVQESDRGWYMCQI-----NTDPM-KSQMGYLDVVVPPDIVDYQTSQ 142

Human   148 YIEAKEGGSITMTCTAFGNPKPIVTWLKEGT---LLGASGK---YQVSDGSLTVTSVSREDRGAY 206
            .:....|.::|:||:|.|.|.|.:||.:|..   |:...|.   :.|...:||:..|.|...|||
  Fly   143 DVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAY 207

Human   207 TCRAYSIQGEAVHTT-----HLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQ 266
            .|    |....|..|     .|:|...|.|.:..:.|.|.:.|...|.|..|:.|.::.: |...
  Fly   208 LC----IASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNF-WLRD 267

Human   267 D--------ENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQY 323
            .        |:|...:..::.:||.:.      .:...|.|:|.|...|::|::   ...:||.:
  Fly   268 SQLLQGGSYESVSVDHVFRIVMRITLR------PITKRDFGEYICRAKNAMGQT---DRIITVHH 323

Human   324 PAR 326
            .|:
  Fly   324 KAK 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IGSF9BNP_001264214.1 IG_like 30..115 CDD:214653 23/94 (24%)
Ig 41..115 CDD:143165 19/77 (25%)
I-set 139..225 CDD:254352 28/97 (29%)
IGc2 153..210 CDD:197706 22/62 (35%)
I-set 229..321 CDD:254352 20/99 (20%)
Ig 235..321 CDD:299845 18/93 (19%)
IG_like 331..414 CDD:214653
Ig <353..414 CDD:299845
IG_like 426..505 CDD:214653
Ig 442..505 CDD:299845
FN3 510..601 CDD:238020
FN3 617..699 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 758..817
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 911..1081
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 22/102 (22%)
Ig 39..122 CDD:299845 22/99 (22%)
Ig 132..213 CDD:299845 26/84 (31%)
IG_like 141..227 CDD:214653 27/89 (30%)
IG_like 239..322 CDD:214653 19/92 (21%)
IGc2 245..313 CDD:197706 15/74 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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